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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Augmentative and Alternative Communication Clear all
Terminated Not applicable Interventional

Storybook Reading in Individuals With Down Syndrome

NCT03764761
View directory record Official record
Conditions
Down Syndrome, Augmentative and Alternative Communication
Interventions
AAC Technology - Standard of Care, AAC Technology - non-optimal integrated arrangement
Device
Lead sponsor
Penn State University
Other
Eligibility
7 Years to 35 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2022 · Synced Jul 22, 2026, 3:55 PM EDT
Enrolling by invitation Not applicable Interventional

Primary Progressive Aphasia Multicomponent Language Treatment Study

NCT06649084
View directory record Official record
Conditions
Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia, Nonfluent Aphasia, Progressive, Aphasia, Aphasia, Progressive
Interventions
Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jul 22, 2026, 3:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth

NCT05743439
View directory record Official record
Conditions
Intellectual Disability, Speech and Language Disorder
Interventions
Early Augmentative and Alternative Communication (AAC) Intervention
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
24 Months and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jul 22, 2026, 3:55 PM EDT
Not yet recruiting Not applicable Interventional

Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals

NCT07581483
View directory record Official record
Conditions
Autism, Neurodevelopment
Interventions
Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
3 Years to 14 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 22, 2026, 3:55 PM EDT
Completed Not applicable Interventional Results available

Vidatalk Communication Application: Usability, Acceptability and Efficacy Study

NCT02921776
View directory record Official record
Conditions
Nonverbal Communication, Critical Illness
Interventions
Aim 1 - VidaTalk - post-extubation, Aim 2 - VidaTalk - intubated, Aim 3 - VidaTalk tablet app, Aim 3 - attention-control with non-VidaTalk tablet
Other · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 99 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Jul 22, 2026, 3:55 PM EDT
Not listed Not applicable Interventional

Using Augmentative & Alternative Communication to Promote Language Recovery for People With Post-Stroke Aphasia

NCT04081207
View directory record Official record
Conditions
Post-stroke Aphasia, Aphasia
Interventions
AAC for Language Recovery (AAC-LaRc)
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Jul 22, 2026, 3:55 PM EDT
Completed No phase listed Observational

Real World Testing of a Brain-Computer Interface

NCT04026581
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury, Speech Disorders
Interventions
Speech generating device (SGD) evaluation including BCI access, Training and treatment
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Carnegie, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Jul 22, 2026, 3:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain-computer Interface Commercial Readiness

NCT06521736
View directory record Official record
Conditions
Non-Verbal Communication, Degenerative Neurologic Disease
Interventions
AAC-BCI device
Device
Lead sponsor
Kendrea Garand
Other
Eligibility
14 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 22, 2026, 3:55 PM EDT
Recruiting Not applicable Interventional

Measuring Aided Language Development

NCT06512168
View directory record Official record
Conditions
Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder, Speech Disorders in Children, Speech and Language Disorder
Interventions
AAC Generative Language Intervention
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
42 Months to 60 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Jul 22, 2026, 3:55 PM EDT
Active, not recruiting Not applicable Interventional

Improving Outcomes Using Technology for Children Who Are DHH

NCT02998164
View directory record Official record
Conditions
Hearing Loss, Language Development, Social Behavior
Interventions
augmentative and alternative communication technology, Usual Care
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 10 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Jul 22, 2026, 3:55 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners

NCT07384156
View directory record Official record
Conditions
Literacy, Communication, Nonverbal
Interventions
ALLSTAR
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
5 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jul 22, 2026, 3:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring Predictors of Response to a Peer-Mediated Intervention for Preschoolers With ASD

NCT05277103
View directory record Official record
Conditions
Autism Spectrum Disorder, Nonverbal Communication
Interventions
Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
3 Years to 6 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 22, 2026, 3:55 PM EDT
Not listed Not applicable Interventional

Effect of the ALL App on Literacy for Children Who Use AAC

NCT05602181
View directory record Official record
Conditions
Literacy
Interventions
ALL Phonics Instruction, ALL Sight Word Instruction
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
3 Years to 10 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Jul 22, 2026, 3:55 PM EDT
Completed Not applicable Interventional

Artificial Intelligence and Augmentative and Alternative Communication AAC

NCT06599996
View directory record Official record
Conditions
Cerebral Palsy, Cortical Visual Impairment
Interventions
Testing artificial intelligence algorithms for interpreting gestures
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Jul 22, 2026, 3:55 PM EDT
Recruiting Not applicable Interventional

Speech Production Enhancement Using Augmentative Communication for Kids

NCT07173049
View directory record Official record
Conditions
Cerebral Palsy (CP), Intelligibility, Speech, Augmentative and Alternative Communication
Interventions
AAC Speech supplementation
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
7 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 22, 2026, 3:55 PM EDT
Recruiting Not applicable Interventional

Intervention for Communication Quality of Life in Primary Progressive Aphasia

NCT07219680
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Semantic Dementia, Logopenic Progressive Aphasia (LPA), Nonfluent Aphasia, Progressive, Progressive Aphasia, Semantic Variant Primary Progressive Aphasia (svPPA), Semantic Aphasia, Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA), Logopenic Progressive Aphasia, Nonfluent Variant Primary Progressive Aphasia (nfvPPA), Nonfluent Progressive Aphasia
Interventions
Multicomponent Lexical Retrieval Cascade Training, Multicomponent Video Implemented Script Training in Aphasia
Behavioral
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jul 22, 2026, 3:55 PM EDT