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Showing 1–24 of 1,092 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Autism Spectrum Disorders Clear all
Completed Not applicable Interventional

Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD

NCT05284435
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorder, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy-Email (iCBT-E), Cognitive Behavioral Therapy-Email and Videoconferencing (iCBT-EV)
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 15 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Cognitive Development in Young Children With Autism

NCT01425918
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social Enhancement Intervention, Parent Education
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
24 Months to 42 Months
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 1, 2026, 6:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Non-Drug Study on the Relationship Between Exploratory Biomarkers and Functional Dimensions in Individuals With Autistic Disorder or Asperger's Syndrome

NCT01669889
View directory record Official record
Conditions
Healthy Volunteer, Autistic Disorder, Asperger's Syndrome
Interventions
Not listed
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
3
States / cities
Los Ageles, California • New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2016 · Synced Sep 1, 2026, 6:29 PM EDT
Recruiting Not applicable Interventional

Transitional Intervention for Hyperacusis in Autism

NCT07798297
View directory record Official record
Conditions
Loudness Hyperacusis, Autism Spectrum Disorder (ASD), Hyperacusis
Interventions
Transitional Intervention for Hyperacusis in Autism
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Orlando, Florida • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Biomarkers Research in Anxiety for Validation and Efficacy

NCT06221176
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Being Brave
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 6 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Portable Visual Guidance System Phase II

NCT00848874
View directory record Official record
Conditions
Asperger Syndrome, High Functioning Autism
Interventions
PVGS
Behavioral
Lead sponsor
Minna Levine, PhD
Industry
Eligibility
11 Years to 21 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2018 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of Pathways Parent-Mediated Early Autism Intervention on Social Attention and Language

NCT05604326
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Pathways Intervention, Parent Education Intervention (PEI)
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
12 Months to 42 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Sep 1, 2026, 6:29 PM EDT
Not yet recruiting Phase 4 Interventional

Semaglutide in Youth With Autism Spectrum Disorder

NCT07770152
View directory record Official record
Conditions
Autism Spectrum Disorder, Obesity
Interventions
Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
Drug · Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Results available

A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders

NCT03730194
View directory record Official record
Conditions
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Sleep Disturbance
Interventions
Melatonin, Bedtime Bank
Dietary Supplement · Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
10 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth

NCT04606966
View directory record Official record
Conditions
Autism Spectrum Disorder, Mental Disorders
Interventions
Therapeutic Horseback Riding, Barn Activity, Hybrid
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
6 Years to 17 Years
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Portland, Maine
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Results available

Oxcarbazepine Versus Placebo in Childhood Autism

NCT00467753
View directory record Official record
Conditions
Autism
Interventions
Oxcarbazepine, Placebo/sugar pill
Drug · Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
5 Years to 17 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Efficacy of IMPACT in Infant Siblings of Children With ASD

NCT03274622
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Impact Parent Training, No Impact
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Months to 18 Months
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 1, 2026, 6:29 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Detection of ASD at the 1st Birthday as Standard of Care: The Get SET Early Model

NCT02463422
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
12 Months to 36 Months
Enrollment
12,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
2
States / cities
Phoenix, Arizona • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorder

NCT01691066
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Infant Toddler Years PRT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Months to 15 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Sep 1, 2026, 6:29 PM EDT
Terminated Phase 2 Interventional Results available

Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)

NCT01592773
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Autism, Autistic Disorder, Asperger's Disorder, Asperger's, Pediatric Autism, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Interventions
Memantine Hydrochloride (HCl)
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
6 Years to 12 Years
Enrollment
747 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
68
States / cities
Dothan, Alabama • Phoenix, Arizona • Tucson, Arizona + 62 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2015 · Synced Sep 1, 2026, 6:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Exome Sequencing in Autistic Spectrum Disorder

NCT01059201
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism, Autistic Disorder
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Not listed
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
3
States / cities
Baltimore, Maryland • Bethesda, Maryland • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Communication in Autism Network

NCT01018407
View directory record Official record
Conditions
Autism
Interventions
Discrete Trial Training, Interpersonal Developmental Approach
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
33 Months to 54 Months
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
3
States / cities
Los Angeles, California • Baltimore, Maryland • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Sensory Integration Therapy in Autism: Mechanisms and Effectiveness

NCT02536365
View directory record Official record
Conditions
Autism
Interventions
Sensory Integration Therapy, Applied Behavioral Analysis
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
6 Years to 114 Months
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

D-Cycloserine and Social Skills Training in Autism Spectrum Disorders

NCT01086475
View directory record Official record
Conditions
Autistic Disorder, Asperger's Disorder, Pervasive Developmental Disorder NOS
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
5 Years to 11 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Indianapolis, Indiana • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

RUPP PI PDD: Drug and Behavioral Therapy for Children With Pervasive Developmental Disorders

NCT00080145
View directory record Official record
Conditions
Child Development Disorders, Pervasive
Interventions
Risperidone, Behavior Therapy
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
4 Years to 13 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
New Haven, Connecticut • Indianapolis, Indiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2013 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Phase 1Phase 2 Interventional Results available

The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism

NCT00695136
View directory record Official record
Conditions
Autism, Cognition Disorder
Interventions
Donepezil hydrochloride, Increase REM sleep percentage
Drug · Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
2 Years to 10 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Sep 1, 2026, 6:29 PM EDT
Not listed Not applicable Interventional

Word Learning in Children With Autism

NCT03419611
View directory record Official record
Conditions
Autistic Disorders Spectrum
Interventions
Multi-Modal, Treatment as Usual, High Intensity Multi-Modal
Behavioral · Other
Lead sponsor
University of Kansas
Other
Eligibility
5 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2019 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children

NCT00468130
View directory record Official record
Conditions
Autism
Interventions
Aripiprazole, Placebos
Drug
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
5 Years to 17 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Sep 1, 2026, 6:29 PM EDT
Completed Not applicable Interventional

Study of the Effectiveness of a Computer Decision Support System to Improve Physicians' Screening for Autism

NCT01612897
View directory record Official record
Conditions
Healthy Children Undergoing Routine Care, Children With Autism
Interventions
Computer based care reminders
Other
Lead sponsor
Indiana University
Other
Eligibility
17 Months to 4 Years
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Sep 1, 2026, 6:29 PM EDT