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ClinicalTrials.gov public records Last synced Oct 26, 2026, 9:26 AM EDT

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Showing 457–480 of 1,106 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Autistic Disorders Spectrum Clear all
Recruiting Not applicable Interventional

Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

NCT06627205
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Autism
Interventions
Sleep Restriction Therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
6 Years to 12 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 26, 2026, 9:26 AM EDT
Active, not recruiting Phase 2 Interventional

ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)

NCT05889273
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
ML-004 (IR)/(ER) tablet
Drug
Lead sponsor
MapLight Therapeutics
Industry
Eligibility
12 Years to 46 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
18
States / cities
Dothan, Alabama • Phoenix, Arizona • Glendale, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed No phase listed Observational

Brain Genomics Superstruct Project

NCT01552460
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2024 · Synced Oct 26, 2026, 9:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Improving Autism Screening With Brain-Related miRNA

NCT02712853
View directory record Official record
Conditions
Autism Spectrum Disorder, Developmental Delay
Interventions
Saliva collection, Vineland Adaptive Behavior Scale-II Assessment
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Months to 6 Years
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Oct 26, 2026, 9:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Microbiome and Mycobiome Registry of Volunteers With and Without Autism Spectrum Disorder

NCT03819439
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Microbiome and Autism Questionnaire
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
2 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 26, 2026, 9:26 AM EDT
Recruiting Early Phase 1 Interventional

Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design

NCT07432776
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Pickleball Program (Community-Based)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Middletown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Phase 2 Interventional Results available

A Study of N-Acetyl Cysteine in Children With Autism

NCT00627705
View directory record Official record
Conditions
Autistic Disorder
Interventions
N-Acetyl Cysteine, Placebo - sugar pill
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
3 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Results available

Community-based Adaptive Autism Intervention for Toddlers

NCT04283045
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
JASPER, JASPER Plus+
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
24 Months to 36 Months
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)

NCT07329257
View directory record Official record
Conditions
Baker Gordon Syndrome, Rare Neurodevelopmental Conditions, Rare Neurogenetic Conditions, Syt-1 Disorder, Epilepsy, Seizure, Genetic Mutations, Autism in Children, Developmental Delay (Disorder)
Interventions
No Intervention: Observational Cohort
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Up to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Recruiting Not applicable Interventional

Implementation of Naturalistic Developmental Behavioral Intervention (NDBI) Through Coaching Caregivers of Young Autistic Children

NCT06923553
View directory record Official record
Conditions
Implementation Research
Interventions
NDBIs
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 26, 2026, 9:26 AM EDT
Recruiting Not applicable Interventional

Differences in Rest, Emotion, and Arousal Modulation in Youth

NCT07476937
View directory record Official record
Conditions
Autism, Sleep Disturbances in Children, Sleep
Interventions
Power Down bedtime manipulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed No phase listed Observational

DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

NCT03718910
View directory record Official record
Conditions
DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
2 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exposure Therapy for Auditory Sensitivity in Autism

NCT03206996
View directory record Official record
Conditions
Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities, Autistic Behavior, Hyperacusis
Interventions
Exposure therapy, Psycho-education, Caregiver education/home program development
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
5 Years to 17 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges

NCT03071120
View directory record Official record
Conditions
Parent-Child Relations, Meals, Autism Spectrum Disorder
Interventions
Parent-Mediated Intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 7 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavior Therapy for Irritability in Autism

NCT04654260
View directory record Official record
Conditions
Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger, Aggression, Asperger Syndrome, Pervasive Developmental Disorder
Interventions
Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Phase 1Phase 2 Interventional

Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders

NCT06368726
View directory record Official record
Conditions
Attention, Visual Perceptual Weakness, Social Behavior, Fluency Disorder, EEG With Periodic Abnormalities
Interventions
tDCS or Transcranial Direct Current Stimulation, Risperidone, Sham tDCS
Device · Drug · Other
Lead sponsor
Spanish Foundation for Neurometrics Development
Other
Eligibility
6 Years to 11 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Autism Access Link for Early Referral and Treatment

NCT04861740
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Autism ALERT, Screening Intervention
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
12 Months to 54 Months
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 26, 2026, 9:26 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth

NCT07494513
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
Interventions
Milieu Teaching-AV, Milieu Teaching-NoAV
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
5 Months to 13 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Phase 1 Interventional

An fMRI Study of the Effect of Intravenous Oxytocin vs. Placebo on Response Inhibition and Face Processing in Autism

NCT00263796
View directory record Official record
Conditions
Autism
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Anagnostou, Evdokia, M.D.
Individual
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Phase 2 Interventional Results available

Riluzole to Treat Child and Adolescent Obsessive-Compulsive Disorder With or Without Autism Spectrum Disorders

NCT00251303
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Autism Spectrum Disorder, Autism, Asperger Disorder, Developmental Disorder
Interventions
Riluzole, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
7 Years to 17 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional

Intervention for Toddlers at Risk for Autism Spectrum Disorders (ASD)

NCT01179841
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Playgroup, Parent Training
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
11 Months to 21 Months
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 26, 2026, 9:26 AM EDT
Terminated Phase 2 Interventional Results available

Impact of Combined Medication and Behavioral Treatment for ASD & ADHD

NCT03242772
View directory record Official record
Conditions
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Amphetamine, ESDM informed parent coaching, Placebo Oral Tablet
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
36 Months to 131 Months
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adapting an Advocacy Services Intervention for Latinx Families of Transition-aged Youth With Autism Spectrum Disorder

NCT06207149
View directory record Official record
Conditions
Autism
Interventions
ASISTIR
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 26, 2026, 9:26 AM EDT
Completed Phase 1 Interventional

Cognitive-Behavioral Therapy for Children With High-Functioning Autism Spectrum Disorder and Anxiety

NCT01187784
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism, Asperger Syndrome, PDD-NOS
Interventions
Coping Cat cognitive-behavioral therapy for anxious youth
Behavioral
Lead sponsor
Alliant International University
Other
Eligibility
7 Years to 14 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2010 · Synced Oct 26, 2026, 9:26 AM EDT