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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: B Vitamin Deficiency Clear all
Withdrawn Phase 1 Interventional

Thiamine Supplementation in Patients With Septic Shock

NCT03122678
View directory record Official record
Conditions
Septic Shock, Shock, Septic, Lactic Acidosis, Thiamine Deficiency
Interventions
Thiamine, Placebos
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Phase 4 Interventional Results available

A Study of Serum Folate Levels in Patients Treated With Olaparib

NCT04024254
View directory record Official record
Conditions
Ovarian Cancer, Breast Cancer, Folic Acid Deficiency
Interventions
Folic Acid Tablet
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed No phase listed Observational Results available

Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans

NCT05480943
View directory record Official record
Conditions
Thiamine Deficiency, Thiamine Deficiency; Sequelae
Interventions
Thiamine repletion
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Consumption of Post-harvest UV-B Treated Mushrooms on Vitamin D Status of Healthy Adults

NCT01443897
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
1,000 IU vitamin D2, placebo capsule, mushrooms, UVB-treated mushrooms, 400 IU vitamin D2, UVB-treated mushrooms, 1,000 IU vitamin D2
Dietary Supplement · Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 59 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2011 · Synced Jul 22, 2026, 2:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Food and Alcohol Behavior Study: Meaningful Enhancement

NCT04095052
View directory record Official record
Conditions
Folate Deficiency
Interventions
Methyl Folate, Placebo
Dietary Supplement
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin

NCT02076347
View directory record Official record
Conditions
Type 2 Diabetes, Vitamin B12 Deficiency, Neuropathy, Anemia
Interventions
Office visit intervention, Electronic Message Intervention
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
489 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 18, 2015 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Clinical and Laboratory Study of Methylmalonic Acidemia

NCT00078078
View directory record Official record
Conditions
Organic Acidemia, Methylmalonic Acidemia, Inborn Errors of Metabolism
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month to 115 Years
Enrollment
2,275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2004
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status

NCT04780776
View directory record Official record
Conditions
Vitamin D Deficiency, Vitamin D Insufficiency
Interventions
UVB treatment, Sham comparator
Device
Lead sponsor
Boston University
Other
Eligibility
22 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Jul 22, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach

NCT05453708
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related, Diet, Healthy, Diet; Deficiency, Folate Deficiency, Folic Acid Deficiency, Folic Acid Overdose
Interventions
Survey
Other
Lead sponsor
Walden University
Other
Eligibility
18 Years and older · Female only
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D

NCT04865432
View directory record Official record
Conditions
Vitamin D Deficiency, Vitamin D Insufficiency
Interventions
UVB treatment
Device
Lead sponsor
Boston University
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency

NCT02553447
View directory record Official record
Conditions
Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, Untreated Chronic Lymphocytic Leukemia, Vitamin D Deficiency
Interventions
Cholecalciferol, Laboratory Biomarker Analysis
Dietary Supplement · Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Not listed No phase listed Observational

A Retrospective Analysis of Cerefolin NAC® in Cognitively Impaired Patients

NCT01594541
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Pamlab, Inc.
Industry
Eligibility
55 Years to 89 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2014 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a B12 Vitamin to Increase Energy and Focus

NCT05517005
View directory record Official record
Conditions
B12 Deficiency Vitamin, Energy Supply; Deficiency, Mood
Interventions
Hype Bites Supplement
Dietary Supplement
Lead sponsor
Sourse
Industry
Eligibility
24 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

NCT03746106
View directory record Official record
Conditions
Vitamin B1 Deficiency, Thiamine Deficiency
Interventions
Trimethoprim, Metformin, Vitamin B1
Drug · Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2025 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Results available

Thiamine as a Renal Protective Agent in Septic Shock

NCT03550794
View directory record Official record
Conditions
Sepsis, Kidney Injury, Thiamine Deficiency
Interventions
Thiamine Hydrochloride, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
4
States / cities
Boston, Massachusetts • Manhasset, New York • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Recruiting Early Phase 1 Interventional

Type 2 Diabetes and Blood Brain Barrier Improvement

NCT06322212
View directory record Official record
Conditions
Type2diabetes
Interventions
Thiamine, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
40 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp

NCT01930539
View directory record Official record
Conditions
Vitamin D Deficiency, Short Bowel Syndrome
Interventions
Ultraviolet B lamp
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants

NCT01864057
View directory record Official record
Conditions
Beriberi
Interventions
thiamine hydrochloride 100 mg
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

NCT00004495
View directory record Official record
Conditions
End Stage Renal Disease, Hyperhomocysteinemia
Interventions
cyanocobalamin, folic acid, pyridoxine
Drug
Lead sponsor
Georgetown University
Other
Eligibility
21 Years to 89 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2000
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2015 · Synced Jul 22, 2026, 2:19 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effects of Vitamin B12 Treatment in Singers

NCT03437824
View directory record Official record
Conditions
Vitamin B 12 Deficiency
Interventions
Cyanocobalamin, Placebo
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jul 22, 2026, 2:19 AM EDT