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Showing 1–24 of 1,172 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Back Ache Clear all
Completed No phase listed Observational Accepts healthy volunteers

Connective Tissue Motion Measure 2

NCT01784094
View directory record Official record
Conditions
Low Back Pain, Musculoskeletal Pain
Interventions
StromaGlide
Device
Lead sponsor
Stromatec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient Response to Spinal Manipulation

NCT01670292
View directory record Official record
Conditions
Low Back Pain
Interventions
HVLA-SM
Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 4, 2017 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Self-Natural Posture Exercise Programs on Chronic Low Back Pain

NCT05136729
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Self-Natural Posture Exercise training
Behavioral
Lead sponsor
Billings Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Billings, Montana
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Phase 2 Interventional Results available

Optimization of Spinal Manipulative Therapy Protocols

NCT02868034
View directory record Official record
Conditions
Low Back Pain
Interventions
SMT, Mobilizing Exercises, Activation Exercises, SMT extended
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Jun 26, 2026, 6:33 AM EDT
Active, not recruiting Not applicable Interventional Results available

Development and Feasibility of Mindfulness Based Pain Reduction

NCT04980612
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Mindfulness Based Pain Reduction, Mindfulness Based Stress Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Positive Piggy Bank - A Positive Activities Intervention for Improving Functional Status in Patients With Back Pain

NCT02476812
View directory record Official record
Conditions
Low Back Pain
Interventions
Positive Piggy Bank
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain

NCT00899600
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ketamine, Normal saline
Drug · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Jun 26, 2026, 6:33 AM EDT
Not listed Phase 1 Interventional

New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain

NCT02008136
View directory record Official record
Conditions
Cervicalgia, Low Back Pain
Interventions
Botulinum Toxins
Drug
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 6, 2017 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Acupuncture Relief for Chronic Neck Pain

NCT03859011
View directory record Official record
Conditions
Neck Pain, Posterior
Interventions
Acupuncture
Other
Lead sponsor
5 Element Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Phase 4 Interventional Results available

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

NCT00880607
View directory record Official record
Conditions
Pain Management, Spinal Fusion, Scoliosis
Interventions
Intrathecal morphine, Extended Release Epidural Morphine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lumbar Injectrode Feasibility Evaluation

NCT06206356
View directory record Official record
Conditions
Chronic Pain, Lower Back Pain Chronic
Interventions
PNS Injectrode F1
Device
Lead sponsor
Neuronoff, Inc
Industry
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Jun 26, 2026, 6:33 AM EDT
Recruiting Not applicable Interventional

Ischemic Preconditioning in Osteoarthritis and Back Pain

NCT07003113
View directory record Official record
Conditions
Low Back Pain, Knee Osteoarthritis
Interventions
Ischemic Preconditioning, Sham Intervention
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jun 26, 2026, 6:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Chronic Opioid Use in Low Back Pain and Lumbar Orthosis Intervention

NCT02241824
View directory record Official record
Conditions
Chronic Lower Back Pain, Chronic Opioid Use
Interventions
In-elastic lumbar brace, Elastic abdominal binder
Device
Lead sponsor
Geoffrey C. Garth
Other
Eligibility
20 Years to 72 Years · Male only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy Study of the Evoke™ SCS System With Feedback vs. Conventional Stimulation

NCT02924129
View directory record Official record
Conditions
Chronic Pain, Back Pain, Pain
Interventions
Evoke Spinal Cord Stimulator (SCS) System
Device
Lead sponsor
Saluda Medical Americas, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
16
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Santa Rosa, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Early Phase 1 Interventional

Combined IV and Topical TXA in Major Spine Surgery

NCT04797156
View directory record Official record
Conditions
Spine Surgery, Back Pain
Interventions
High Dose Tranexamic acid, Low Dose Tranexamic acid, Tranexamic acid Topical, Normal saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Phase 4 Interventional Results available

ADAPT: Addressing Depression and Pain Together

NCT01124188
View directory record Official record
Conditions
Depression, Back Pain
Interventions
Higher-dose venlafaxine, Supportive management, Problem Solving Therapy for Depression and Pain
Drug · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Jun 26, 2026, 6:33 AM EDT
Terminated Phase 4 Interventional Results available

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

NCT00619983
View directory record Official record
Conditions
Diabetic Neuropathic Pain, Chronic Low Back Pain
Interventions
donepezil, duloxetine, donepezil 2.5 mg and duloxetine 30mg, placebo, gabapentin
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional

Modifiable Work and Movement Solutions Low Back Pain in Seafood Workers

NCT03524378
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Ergonomic and movement modifications
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Cedar Key, Florida • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional

To Evaluate Success of Cement Treatment of Spinal Compression Fractures

NCT00166374
View directory record Official record
Conditions
Back Pain
Interventions
balloon kyphoplasty
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2010 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Not applicable Interventional Results available

Management Strategies for Patients With Low Back Pain and Sciatica

NCT02391350
View directory record Official record
Conditions
Low Back Pain, Sciatica, Physical Therapy
Interventions
Education and re-assurance, Physical Therapy
Behavioral · Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 21, 2021 · Synced Jun 26, 2026, 6:33 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation

NCT00000410
View directory record Official record
Conditions
Herniated Disc, Low Back Pain
Interventions
Diskectomy, Non-surgical treatments
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Jun 26, 2026, 6:33 AM EDT
Active, not recruiting Phase 4 Interventional

Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain

NCT03888820
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Biofreeze, Placebo
Drug
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Jun 26, 2026, 6:33 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Trial of Levator Muscle Blocks Following Posterior Colporrhaphy Surgery to Reduce Post-operative Pain.

NCT03067168
View directory record Official record
Conditions
Post Operative Pain
Interventions
Bupivacaine, normal saline 0.9%
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Kansas City, Kansas • Cincinnati, Ohio • Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2019 · Synced Jun 26, 2026, 6:33 AM EDT
Terminated Not applicable Interventional

Dynamic Stabilization for Lumbar Spinal Stenosis With Stabilimax NZ® Dynamic Spine Stabilization System

NCT00529997
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Stabilimax NZ® Dynamic Spine Stabilization System
Device
Lead sponsor
Applied Spine Technologies
Industry
Eligibility
21 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
19
States / cities
Phoenix, Arizona • Los Angeles, California • Oceanside, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2010 · Synced Jun 26, 2026, 6:33 AM EDT