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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:40 AM EDT

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Showing 217–240 of 1,190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Back Pain Clear all
Completed Not applicable Interventional

Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain

NCT02170753
View directory record Official record
Conditions
Low Back Pain, Musculoskeletal Pain
Interventions
Regional manual therapy, Standard physical therapy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 27, 2016 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Phase 3 Interventional Results available

A Study for Patient With Chronic Low Back Pain

NCT00767806
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
7
States / cities
Chandler, Arizona • Cromwell, Connecticut • DeLand, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2010 · Synced Oct 23, 2026, 3:40 AM EDT
Suspended Not applicable Interventional

The Influence of a Protein Nutrition Beverage on Exercise-based Rehabilitation Outcomes in Individuals with Spine Pain.

NCT04829448
View directory record Official record
Conditions
Low Back Pain
Interventions
Protein supplement
Dietary Supplement
Lead sponsor
Kamshad Raiszadeh, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 23, 2026, 3:40 AM EDT
Recruiting Phase 1 Interventional

Adia Med of Winter Park LLC Lower Back Pain Research Study

NCT07587047
View directory record Official record
Conditions
Chronic Mechanical Lower Back Pain, Lower Back Pain, Chronic Lower Back Pain
Interventions
Umbilical Cord Blood-Derived Stem Cells and Exosomes, Placebo IV
Biological · Other
Lead sponsor
Adia Med of Winter Park LLC
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winter Park, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Phase 2 Interventional Results available

D-cycloserine in the Management of Chronic Low Back Pain

NCT00125528
View directory record Official record
Conditions
Low Back Pain, Pain
Interventions
D-cycloserine, placebo
Drug
Lead sponsor
Thomas J. Schnitzer
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Oct 23, 2026, 3:40 AM EDT
Not listed Phase 1Phase 2 Interventional

The Effects of Short Arc Banding

NCT00885001
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Short Arc Banding
Procedure
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2009 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Phase 4 Interventional Results available

Spinal Cord Stimulation (SCS) Dosing Study

NCT03284411
View directory record Official record
Conditions
Back Pain, Leg Pain
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
MedtronicNeuro
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
10
States / cities
Chandler, Arizona • Lawrenceville, Georgia • Evansville, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Oct 23, 2026, 3:40 AM EDT
Not yet recruiting Phase 4 Interventional

ESP Blocks for Posterior Spinal Fusion

NCT07228039
View directory record Official record
Conditions
Postoperative Pain
Interventions
ESP Block with Bupivacaine, ESP Block with Bupivacaine + Liposomal Bupivacaine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Comparing Dry Needling to Manual Therapy for Patients With Mechanical Low Back Pain

NCT02312895
View directory record Official record
Conditions
Low Back Pain
Interventions
Manual therapy, Dry needling, Home Exercise Program
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years to 70 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Phase 4 Interventional

Pilot Study of the Efficacy and Safety of Lidoderm Patch in the Treatment of Low Back Pain

NCT00904475
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Lidoderm®
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
6
States / cities
Birmingham, Alabama • Hueytown, Alabama • Phoenix, Arizona + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2010 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Effectiveness of Adding Behavioral Therapy to Physical Therapy to Treat Low Back Pain

NCT00373867
View directory record Official record
Conditions
Low Back Pain
Interventions
Standard physical therapy, Graded exercise, Graded exposure
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
15 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2013 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Optimizing Chronic Pain Management Through Patient Engagement With Quality of Life Measures

NCT04168437
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Health-Related Quality of Life Report
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 79 Years
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimal Stimulation Programming for Spinal Peripheral Neuromodulation

NCT02346383
View directory record Official record
Conditions
Chronic Pain
Interventions
preset program
Device
Lead sponsor
Carolinas Center for Advanced Management of Pain
Other
Eligibility
22 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Battlefield Acupuncture for the Treatment of Low Back Pain in the Emergency Department

NCT02399969
View directory record Official record
Conditions
Low Back Pain
Interventions
Battlefield Acupuncture
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Feasibility Assessment of Neurophysiological Measurement in Veterans With LBP

NCT02375386
View directory record Official record
Conditions
Low Back Pain
Interventions
Spinal manipulation, Therapeutic touch, fMRI, Pain Sensitivity Testing, Questionnaires, Physical Impairment
Procedure · Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Oct 23, 2026, 3:40 AM EDT
Recruiting Not applicable Interventional

Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain

NCT07278570
View directory record Official record
Conditions
Myofascial Pain Syndrome - Lower Back, Myofascial Pain
Interventions
Tuina treatment, Usual care
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 23, 2026, 3:40 AM EDT
Completed No phase listed Observational

Cost Effectiveness of OMT for Chronic Low Back Pain

NCT03532230
View directory record Official record
Conditions
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis, Lumbar Spondylosis, Lumbago With Sciatica, Left Side, Lumbago With Sciatica, Right Side
Interventions
Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 84 Years
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Oct 23, 2026, 3:40 AM EDT
Terminated Not applicable Interventional Results available

Peripheral Nerve Stimulation for Back

NCT04538430
View directory record Official record
Conditions
Back Pain
Interventions
SPRINT percutaneous peripheral nerve stimulator placed
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 6, 2022 · Synced Oct 23, 2026, 3:40 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures

NCT03651804
View directory record Official record
Conditions
Vertebral Compression Fracture, Facet Joint Pain
Interventions
Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates, Acetaminophen, Physical therapy, Opioids
Procedure · Drug · Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 23, 2026, 3:40 AM EDT
Completed No phase listed Observational

Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

NCT05811143
View directory record Official record
Conditions
Lipomatosis, Low Back Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Conventional and Long Pulse Widths During a Temporary Spinal Cord Stimulation Trial

NCT03526055
View directory record Official record
Conditions
Spinal Cord Stimulation, Pain, Back, Pain
Interventions
Algovita Spinal Cord Stimulation System
Device
Lead sponsor
Amol Soin
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Centerville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional

The Feasibility of Using Neuroscience Education in Adults Over 65 Years Old With Chronic Low Back and/or Lower Extremity Pain

NCT02449876
View directory record Official record
Conditions
Back Pain, Lower Extremity Pain
Interventions
Neuroscience Education
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Oct 23, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Orthotic Use for Chronic Low Back Pain

NCT00976664
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Shoe orthotic, Shoe Orthotic Wait Group
Device
Lead sponsor
National University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 23, 2026, 3:40 AM EDT
Completed No phase listed Observational

Mind Your Pain: Validating a Mindful Interoceptive Exposure Task for Patients With Chronic Low Back Pain

NCT06186193
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
MyP
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2023 · Synced Oct 23, 2026, 3:40 AM EDT