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ClinicalTrials.gov public records Last synced Oct 24, 2026, 10:53 AM EDT

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Showing 409–432 of 1,190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Back Pain Clear all
Completed Phase 4 Interventional

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

NCT05142267
View directory record Official record
Conditions
Opioid Use Disorder, Back Pain, Stress
Interventions
Placebo, Oxycodone, Naloxone
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives.

NCT01251263
View directory record Official record
Conditions
Menstrual Migraines, Menstrual Bleeding, Menstrual Spotting
Interventions
Estradiol or Placebo
Drug
Lead sponsor
Scott and White Hospital & Clinic
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2010 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TENS Efficacy on Acute Back Pain in an Emergency Department Triage

NCT03905681
View directory record Official record
Conditions
Acute Back Injury
Interventions
Transcutaneous Electrical Nerve Stimulation
Device
Lead sponsor
William Beaumont Army Medical Center
Federal
Eligibility
18 Years to 59 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Fort Bliss, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prenatal Yoga for Pregnancy Related Back Pain

NCT03651232
View directory record Official record
Conditions
Pregnancy Related
Interventions
yoga, support group
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 29, 2018 · Synced Oct 24, 2026, 10:53 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Mechanical Decompression for Low Back Pain Relief

NCT00704210
View directory record Official record
Conditions
Low Back Pain
Interventions
SpineMed Table, Cert HealthSciences LLC
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Results available

Intraoperative Neuromonitoring Recording With a Novel SCS Paddle

NCT05045625
View directory record Official record
Conditions
Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
Interventions
HD Study Electrode
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 24, 2026, 10:53 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study

NCT04015791
View directory record Official record
Conditions
Lumbar Disc Disease
Interventions
NOCISCAN-LS Disc MR Spectroscopy
Other
Lead sponsor
Nocimed, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2022 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)

NCT00386243
View directory record Official record
Conditions
Low Back Pain, Pain, Pain, Intractable
Interventions
Cognitive behavioral therapy, Pain self-management program, Co-Analgesic Therapy, Opioid Analgesics
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Development of a Cognitive Reassurance Training Program

NCT03256617
View directory record Official record
Conditions
Low Back Pain
Interventions
Cognitive reassurance training
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 24, 2026, 10:53 AM EDT
Recruiting Not applicable Interventional

Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.

NCT04730700
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Radiofrequency Ablation with MEE, Conventional Medical Management
Procedure · Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Wearable Spine Assessment in Adults With and Without Low Back or Neck Pain

NCT07643207
View directory record Official record
Conditions
Low Back Pain, Neck Pain
Interventions
Not listed
Lead sponsor
Ashkan Vaziri
Industry
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Newton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery

NCT04549090
View directory record Official record
Conditions
Post-operative Pain, Gynecologic Surgery, Regional Anesthesia
Interventions
QL (quadratus lumborum) block administration
Drug
Lead sponsor
Pedram Bral
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated Phase 4 Interventional Results available

Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain

NCT05409443
View directory record Official record
Conditions
Sacroiliac Joint Complex, Low Back Pain
Interventions
Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

NCT01358526
View directory record Official record
Conditions
Low Back Pain
Interventions
Oxycodone/Naloxone Controlled-release, Placebo
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
1,095 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
151
States / cities
Birmingham, Alabama • Haleyville, Alabama • Huntsville, Alabama + 123 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2015 · Synced Oct 24, 2026, 10:53 AM EDT
Active, not recruiting No phase listed Observational

Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers

NCT06225583
View directory record Official record
Conditions
Bertolotti's Syndrome, Lower Back Pain
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated Not applicable Interventional

Algovita Spinal Cord Stimulation System Hi-Fi Study

NCT03622866
View directory record Official record
Conditions
Chronic Pain
Interventions
Ultra-high pulse width stimulation, Traditional pulse width stimulation
Device
Lead sponsor
Nuvectra
Industry
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
10
States / cities
Tucson, Arizona • Newport Beach, California • Santa Rosa, California + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Epidural Clonidine Versus Corticosteroid for Low Back Pain

NCT02239627
View directory record Official record
Conditions
Back Pain
Interventions
Epidural steroid, Clonidine
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2021 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS

NCT02550561
View directory record Official record
Conditions
Interstitial Cystitis, Painful Bladder Syndrome
Interventions
Posterior Tibial Nerve Stimulation
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional Results available

Implementation of Pedometer for Monitoring Step Count Pre and Post Lumbar ESI for Radicular Pain

NCT02356783
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Pedometer
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 24, 2026, 10:53 AM EDT
Recruiting Not applicable Interventional

Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

NCT05556902
View directory record Official record
Conditions
Blood Pressure, Low Back Pain, Hypertension
Interventions
Permanent Epidural Spinal Cord Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated No phase listed Observational

The Diagnostic Accuracy of the Clinical Examination

NCT03850470
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
clinical examination, MRI
Diagnostic Test · Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 27, 2021 · Synced Oct 24, 2026, 10:53 AM EDT
Terminated Not applicable Interventional Results available

A Pilot Project for Multifidus Muscle Evaluation in Patients With Multiple Sclerosis

NCT05427045
View directory record Official record
Conditions
Multiple Sclerosis, Back Pain
Interventions
home - exercise program
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 50 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Not applicable Interventional

Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches

NCT06505005
View directory record Official record
Conditions
Pain, Back, Pain, Acute, Sleep Disorder, Sleep Disorders, Circadian Rhythm, Sleep, Sleep Deprivation, Insomnia
Interventions
Drug- free, non-invasive patch (FREEDOM or REM Patch) with haptic vibrotactile trigger technology (VTT) Other Names:, Sham Patch without haptic vibrotactile trigger technology (VTT)
Device
Lead sponsor
SuperPatch Limited LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tyrone, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 10:53 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lumbar Injectrode Feasibility Evaluation

NCT06206356
View directory record Official record
Conditions
Chronic Pain, Lower Back Pain Chronic
Interventions
PNS Injectrode F1
Device
Lead sponsor
Neuronoff, Inc
Industry
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 24, 2026, 10:53 AM EDT