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ClinicalTrials.gov public records Last synced Oct 23, 2026, 12:13 AM EDT

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Showing 121–144 of 1,190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Back Pain Clear all
Recruiting Not applicable Interventional

Transcutaneous Auricular Neurostimulation After Lumbar Surgery

NCT06100172
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use, Lumbar Spine Injury
Interventions
Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN), Sham Control Device
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Treatment for Sacroiliac Joint Pain Using Platelet-rich Plasma (PRP) Versus Steroid/Anesthetic

NCT05121961
View directory record Official record
Conditions
Low Back Pain, Sacroiliac Joint Synovitis
Interventions
Sacroiliac intra-articular injection
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available

Digital Clinical Hypnosis for Chronic Pain Management

NCT06050083
View directory record Official record
Conditions
Chronic Low-back Pain, Chronic Pain
Interventions
Hypnosis audio recordings
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available

Comparison of Extensible and Inextensible Lumbosacral Orthoses for Lower Back Pain

NCT01933399
View directory record Official record
Conditions
Low Back Pain
Interventions
Inextensible LSO (stiff back support), Extensible LSO, a back support that is flexible, Standard of Care
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults

NCT04785963
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Sleep, Aging
Interventions
Music with Suggestion, Pain Information, Music
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
50 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Phase 3 Interventional Results available

The Safety and Efficacy of the Buprenorphine Transdermal System (BTDS) in Subjects With Chronic Back Pain.

NCT00315445
View directory record Official record
Conditions
Back Pain
Interventions
Buprenorphine transdermal patch, Placebo oxycodone/acetaminophen tablets, OXY/APAP, Placebo transdermal patch (TDS)
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 1998
U.S. locations
12
States / cities
Huntsville, Alabama • Phoenix, Arizona • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2012 · Synced Oct 23, 2026, 12:13 AM EDT
Terminated Phase 4 Interventional Results available

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

NCT05552443
View directory record Official record
Conditions
Pain Control
Interventions
Hydromorphone 2.5 mcg/kg, Hydromorphone 2.75 mcg/kg, Hydromorphone 3 mcg/kg, Hydromorphone 3.25 mcg/kg, Hydromorphone 3.5 mcg/kg, Hydromorphone 4 mcg/kg, Hydromorphone 4.5 mcg/kg, Hydromorphone 5 mcg/kg, Hydromorphone 5.5 mcg/kg, Hydromorphone 6 mcg/kg, Hydromorphone 6.5 mcg/kg, Hydromorphone 7 mcg/kg
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
10 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Recruiting Not applicable Interventional

Comparing Yoga Nidra, Yoga, and Control Condition on Pain in Individuals With Chronic Low Back Pain

NCT07543835
View directory record Official record
Conditions
Low Back Pain
Interventions
Yoga, Yoga Nidra, Control Condition
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Terminated Phase 4 Interventional Results available

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

NCT00619983
View directory record Official record
Conditions
Diabetic Neuropathic Pain, Chronic Low Back Pain
Interventions
donepezil, duloxetine, donepezil 2.5 mg and duloxetine 30mg, placebo, gabapentin
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Manipulation of the Cervical Spine on Pain Biomarkers

NCT03176654
View directory record Official record
Conditions
Neck Pain, Posterior
Interventions
HVLAT manipulation, Sham HVLAT manipulation
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Phase 4 Interventional

A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain

NCT00904020
View directory record Official record
Conditions
Postherpetic Neuralgia, Diabetic Neuropathy, Low Back Pain
Interventions
Lidoderm
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
11
States / cities
Birmingham, Alabama • Phoenix, Arizona • Plantation, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Meditation and Exercise to Treat Chronic Back Pain

NCT03324659
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Exercise and Meditation, Control
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
18 Years to 60 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 23, 2026, 12:13 AM EDT
Terminated Phase 2 Interventional Results available

Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury

NCT02736890
View directory record Official record
Conditions
Neuropathic Back Pain, Spinal Cord Injury
Interventions
Botulinum Toxin A, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 23, 2026, 12:13 AM EDT
Not listed Not applicable Interventional

STIMFIX Trail Lead Anchor System for Dorsal Column Stimulator Trail Leads (SECURE Study)

NCT05651646
View directory record Official record
Conditions
Pain
Interventions
Intervention Arm (STIMFIX)
Other
Lead sponsor
STIMFIX
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Lake Havasu City, Arizona • Los Angeles, California • Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Recurrent Low Back Pain: Linking Mechanism to Outcomes (RCT)

NCT01360359
View directory record Official record
Conditions
Low Back Pain
Interventions
Core Stabilization, Trunk Motion and Fitness
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • West Chester, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

The Use of Manual Therapy to Treat Low-Back and Hip Pain

NCT00410397
View directory record Official record
Conditions
Low Back Pain, Pain
Interventions
Osteopathic Manipulative Medicine, Sham Manipulation
Procedure
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 15, 2008 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Standing Trunk Extension and Spinal Height in Low Back Pain

NCT03785457
View directory record Official record
Conditions
Low Back Pain
Interventions
Repetitive Trunk Extension, Sustained Trunk Extension
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Fredericksburg, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 23, 2026, 12:13 AM EDT
Recruiting Not applicable Interventional

Trial to Test the Efficacy of Using Magnetic Fields to Stimulate the Back to Treat Chronic Lower Back Pain.

NCT07652944
View directory record Official record
Conditions
Lower Back Pain Chronic
Interventions
peripheral magnetic stimulation, Home exercise
Device · Behavioral
Lead sponsor
Joe X. Zhang
Federal
Eligibility
18 Years to 64 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Edwards Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Completed No phase listed Observational

Blood Sample Donations to Study the Role of Genes in Pain

NCT00341367
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
Not listed
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
1
States / cities
South Portland, Maine
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 23, 2026, 12:13 AM EDT
Terminated Phase 4 Interventional Results available

Intradiscal Platelet Rich Plasma

NCT04544709
View directory record Official record
Conditions
Discogenic Pain, Low Back Pain, Chronic Pain
Interventions
Low back intradiscal injection of platelet rich plasma (PRP)
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Oct 23, 2026, 12:13 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration

NCT04134910
View directory record Official record
Conditions
Back Pain, Intervertebral Disc Degeneration
Interventions
Physical Therapy
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 23, 2026, 12:13 AM EDT
Terminated Not applicable Interventional

Feasibility of Telehealth Mindfulness for Back Pain in the Emergency Department

NCT04783532
View directory record Official record
Conditions
Low Back Pain, Back Pain, Pain, Chronic Low-back Pain
Interventions
Telehealth Mindfulness Program
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 31, 2022 · Synced Oct 23, 2026, 12:13 AM EDT
Completed No phase listed Observational

The U.S. Embryologist Fatigue Study

NCT05326802
View directory record Official record
Conditions
Fatigue, Stress, Burnout, Professional, Musculoskeletal Pain, Back Pain, Neck Pain, Headache, Dizziness, Sleep Disturbance, Chest Pain, Syncope, Cardiovascular Diseases, Shortness of Breath, Gastrointestinal Diseases
Interventions
Not listed
Lead sponsor
TMRW Life Sciences
Industry
Eligibility
22 Years to 65 Years
Enrollment
246 participants
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 23, 2026, 12:13 AM EDT
Completed Not applicable Interventional

Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain

NCT04494698
View directory record Official record
Conditions
Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
Interventions
Duotherm VibraCool Back Device, TENS 8-channel unit
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Landover, Maryland • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 23, 2026, 12:13 AM EDT