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ClinicalTrials.gov public records Last synced Oct 23, 2026, 1:32 AM EDT

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Showing 145–168 of 1,190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Back Pain Clear all
Recruiting Phase 3 Interventional

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

NCT06027099
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
Interventions
Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care
Drug · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Stanford, California • Kansas City, Kansas • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Not listed Not applicable Interventional

The Enso Study for Chronic Low Back Pain

NCT03320863
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Enso device
Device
Lead sponsor
Thimble Bioelectronics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Results available

Hippocampal Stimulation in Chronic Low Back Pain

NCT04888494
View directory record Official record
Conditions
Chronic Pain, Back Pain, Pain
Interventions
Transcranial Magnetic Stimulation, Sham rTMS
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Phase 4 Interventional Results available

Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.

NCT04611529
View directory record Official record
Conditions
Low Back Pain
Interventions
Ibuprofen 400 mg, Topical diclofenac
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain

NCT00487266
View directory record Official record
Conditions
Low Back Pain
Interventions
Acupuncture
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 23, 2026, 1:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain

NCT00732394
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MSDR
Other
Lead sponsor
MedAppraise, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2008 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional

Wireless Spinal Cord Stimulation for Chronic Pain

NCT02514590
View directory record Official record
Conditions
Back Pain
Interventions
Freedom SCS System
Device
Lead sponsor
Curonix LLC
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
7
States / cities
Beverly Hills, California • Los Angeles, California • Orlando, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Phase 3 Interventional

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

NCT01427283
View directory record Official record
Conditions
Low Back Pain
Interventions
Oxycodone/Naloxone controlled-release, Oxycodone HCl controlled-release, Placebo
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
149
States / cities
Alabaster, Alabama • Birmingham, Alabama • Foley, Alabama + 114 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2015 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Phase 3 Interventional

Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain

NCT00228605
View directory record Official record
Conditions
Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
Interventions
OraVescent Fentanyl
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
38
States / cities
Calera, Alabama • Hoover, Alabama • Phoenix, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heat Wrap Device Safety With Age and Body Fat

NCT01355653
View directory record Official record
Conditions
Back Pain
Interventions
thermal therapy, ThermaCare heatwrap
Device
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 84 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional

Examining Effects of Aerobic Exercise on Pain Sensation

NCT03546153
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2019 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Phase 4 Interventional Results available

Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin

NCT01977937
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
10 Years to 19 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Oct 23, 2026, 1:32 AM EDT
Completed No phase listed Observational

PNE Delivered With a VR Headset in Outpatient LBP Patients

NCT04777877
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain Neuroscience Education delivered via a Virtual Reality Headset
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Results available

Value of Multiple Modalities Using the Spectra WaveWriter Spinal Cord Stimulator System

NCT03251937
View directory record Official record
Conditions
Chronic Pain, Back Pain
Interventions
Spectra WaveWriter SCS System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
22 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
15
States / cities
Napa, California • Jupiter, Florida • Ocala, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Oct 23, 2026, 1:32 AM EDT
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Completed No phase listed Observational

Real-World Experience of Patients Treated for Musculoskeletal Injuries With SAM in Routine Care

NCT05254470
View directory record Official record
Conditions
Musculoskeletal Injury, Pain, Chronic, Pain, Acute, Sport Injury, Soft Tissue Injuries, Arm Injury, Back Pain, Tendon Injuries, Muscle Injury
Interventions
Continuous Ultrasound
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fairfield, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 24, 2022 · Synced Oct 23, 2026, 1:32 AM EDT
Not yet recruiting Not applicable Interventional

Magnetic Resonance Elastography Of Chronic Low Back Pain Before And After Therapy

NCT07712458
View directory record Official record
Conditions
Low Back Pain, Recurrent, Chronic Low Back Pain (CLBP)
Interventions
EMMA (Expert Manipulative Massage Automation)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Phase 4 Interventional Results available

Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

NCT02886286
View directory record Official record
Conditions
Pain, Intractable, Breakthrough Pain, Chronic Pain
Interventions
Bupivacaine, Opioid
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
31 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional

Chronic Low Back Pain Graded - Exposure Psychoeducation Intervention

NCT03909048
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Interactive - Psychoeducation, Non-interactive Psychoeducation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Oct 23, 2026, 1:32 AM EDT
Not yet recruiting Not applicable Interventional

Treatment of Chronic Lower Back Pain With a Combination of Electrical Stimulation, LED, and Laser Therapy

NCT07313826
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Active Neurolumen, Inactive Neurolumen
Device
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Results available

Validation of the STarT Back Screening Tool in the Military

NCT03127826
View directory record Official record
Conditions
Low Back Pain, Lumbago, Radiculopathy, Intervertebral Disc Disorder
Interventions
Risk Stratified Care, Usual Care
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Results available

Interactive Voice Response (IVR)-Based Treatment for Chronic Low Back Pain

NCT01025752
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Face to face cognitive behavior therapy, IVR based cognitive behavioral therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 23, 2026, 1:32 AM EDT
Terminated Phase 3 Interventional

Standardizing Management of Patients With Low Back Pain in Primary Care and Physical Therapy

NCT00769626
View directory record Official record
Conditions
Back Pain, Low Back Pain
Interventions
Usual Care, Early Treatment
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
3
States / cities
South Jordan, Utah • Taylorsville, Utah • West Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Jul 18, 2011 · Synced Oct 23, 2026, 1:32 AM EDT
Completed Not applicable Interventional Results available

Chiropractic Manipulation and Medical Care for Low Back Pain

NCT01211613
View directory record Official record
Conditions
Low Back Pain
Interventions
Manual Manipulation, Mechanically-assisted manipulation, Standard Medical Care
Procedure · Device · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Oct 23, 2026, 1:32 AM EDT