- Conditions
- Chronic Low Back Pain, Opioid-induced Hyperalgesia
- Interventions
- Morphine, Placebo
- Drug
- Lead sponsor
- National Institute of General Medical Sciences (NIGMS)
- NIH
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2009
- U.S. locations
- 1
- States / cities
- Stanford, California
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 864
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Chronic Pain
- Interventions
- Oxymorphone Extended Release
- Drug
- Lead sponsor
- Endo USA Inc., a Keenova Therapeutics Company
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2005
- U.S. locations
- 31
- States / cities
- Hueytown, Alabama • Phoenix, Arizona • Colorado Springs, Colorado + 26 more
- Conditions
- Chronic Low Back Pain
- Interventions
- Active Neurolumen, Inactive Neurolumen
- Device
- Lead sponsor
- Defense and Veterans Center for Integrative Pain Management
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Portsmouth, Virginia
- Conditions
- Acute Low Back Pain
- Interventions
- Naproxen, Cyclobenzaprine, Oxycodone/ acetaminophen
- Drug
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 21 Years to 64 Years
- Enrollment
- 323 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Low Back Pain
- Interventions
- Orphenadrine, Methocarbamol, Naproxen, Placebo
- Drug
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years to 69 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Low Back Pain
- Interventions
- Patient Education, Control
- Behavioral · Other
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Low Back Pain, Knee Osteoarthritis
- Interventions
- Ischemic Preconditioning, Sham Intervention
- Device
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Low Back Pain, Neck Pain
- Interventions
- Engagement of clinic leadership (System Intervention - Usual Care), Engagement of clinic leadership (System Intervention - STEPPT), Patient Registry (System Intervention - STEPPT), Delivery of Patient Education Materials (System Intervention - Usual Care), Delivery of Patient Education Materials (System Intervention - STEPPT), Referral Specialist Training (System Intervention - Usual Care), Patient Health Navigator Training (System Intervention - STEPPT), Care Navigation (System Intervention - STEPPT), Care navigation audit and feedback (System Intervention - STEPPT), Primary Care Provider training (Provider Intervention - STEPPT), Nurse/Medical Assistant Training (Provider Intervention - STEPPT), Provider feedback on PT referral and adherence (Provider Intervention - STEPPT), Patient education on spine pain condition (Patient Intervention - Usual Care), Patient education on spine pain condition (Patient Intervention - STEPPT), Patient Education on Physical Referral by Providers (Patient Intervention - Usual Care), Patient Education on Physical Referral by Providers (Patient Intervention - STEPPT), Electronic Patient Education on Physical Therapy Referral (Patient Intervention - STEPPT), Patient education on physical therapy referral by Referral Specialist (Patient Intervention - Usual Care), Patient education on physical therapy referral by Patient Health Navigator (Patient Intervention - STEPPT), Care Navigation (System Intervention - Usual Care), Monitoring of PT referral and adherence rates (System Intervention - STEPPT), Monitoring of PT referral and adherence rates (System intervention - Usual Care)
- Behavioral
- Lead sponsor
- San Diego State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 17,587 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Pregnancy Related Low Back Pain
- Interventions
- acupuncture, Sham acupuncture, standard of care
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 13 Years to 46 Years · Female only
- Enrollment
- 159 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2008
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Central Sensitization, Low Back Pain, Pain Catastrophizing
- Interventions
- Pain Verbalization Repression Rules
- Behavioral
- Lead sponsor
- Keystone Rehabilitation Systems
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Chronic Low Back Pain
- Interventions
- Basivertebral Nerve (BVN) Ablation
- Device
- Lead sponsor
- Relievant Medsystems, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 13
- States / cities
- Phoenix, Arizona • Daly City, California • Long Beach, California + 10 more
- Conditions
- Chronic Pain
- Interventions
- Not listed
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Low Back Pain, Back Pain With Radiation, Back Pain Without Radiation, Back Pain Lower Back Chronic, Back Ache, Pain, Chronic
- Interventions
- Minocycline Hydrochloride 100mg Capsule, Magnetic Resonance-Positron Emission Tomography Imaging, Placebo Capsule
- Drug · Diagnostic Test · Other
- Lead sponsor
- Marco Loggia
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 1
- States / cities
- Charlestown, Massachusetts
- Conditions
- Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
- Interventions
- Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
- Behavioral · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 360 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Low Back Pain
- Interventions
- Physical therapy
- Other
- Lead sponsor
- Brooke Army Medical Center
- Federal
- Eligibility
- 18 Years to 64 Years
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Fort Sam Houston, Texas
- Conditions
- Low Back Pain
- Interventions
- Intracept Procedure
- Procedure
- Lead sponsor
- Relievant Medsystems, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Discogenic Low Back Pain
- Interventions
- PerQdisc
- Device
- Lead sponsor
- Spinal Stabilization Technologies
- Industry
- Eligibility
- 22 Years to 70 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 8
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 4 more
- Conditions
- Chronic Low Back Pain
- Interventions
- Intracept System Ablation
- Device
- Lead sponsor
- Relievant Medsystems, Inc.
- Industry
- Eligibility
- 25 Years to 70 Years
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Chronic Low Back Pain (CLBP)
- Interventions
- Dry needling
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Chronic Pain, Low Back Pain
- Interventions
- Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus), Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)
- Combination Product
- Lead sponsor
- Evon Medics LLC
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 86 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Low Back Pain
- Interventions
- Caudal epidural injection, Percutaneous adhesiolysis
- Procedure
- Lead sponsor
- Pain Management Center of Paducah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2013
- U.S. locations
- 1
- States / cities
- Paducah, Kentucky
- Conditions
- Chronic Low-back Pain
- Interventions
- Digital program, Conventional physical therapy
- Device · Other
- Lead sponsor
- Sword Health, SA
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Chronic Low Back Pain
- Interventions
- MBM, VNSM
- Behavioral · Device
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Low Back Pain, Zygapophyseal Joint Arthritis
- Interventions
- Normal saline infusion, Naloxone infusion
- Drug
- Lead sponsor
- Middle Tennessee Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee