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ClinicalTrials.gov public records Last synced Oct 28, 2026, 3:40 AM EDT

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Showing 289–312 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Backache Clear all
Completed Not applicable Interventional Results available

Patient-Centered Pain Care Using Artificial Intelligence and Mobile Health Tools

NCT02464449
View directory record Official record
Conditions
Back Pain
Interventions
Behavioral: AI-CBT, Behavioral: Standard Telephone CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
West Haven, Connecticut • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis

NCT01052571
View directory record Official record
Conditions
Low Back Pain
Interventions
lumbar transforaminal epidural injections
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Translation of Robotic Apparel for Alleviating Low Back Pain

NCT05736393
View directory record Official record
Conditions
Low Back Pain
Interventions
Back Exosuit
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Not listed No phase listed Observational

Assessing the Functional Movement Screen as a Reliable Physical Therapy Discharge Criteria for Chronic Lower Back Pain Patients

NCT06474429
View directory record Official record
Conditions
Chronic Lower Back Pain
Interventions
Not listed
Lead sponsor
Texas Back Institute
Other
Eligibility
18 Years to 49 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 1 Interventional

Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain

NCT06218407
View directory record Official record
Conditions
Chronic Pain, Low Back Pain
Interventions
Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm, Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus), Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)
Combination Product
Lead sponsor
Evon Medics LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 4 Interventional Results available

Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain

NCT03761277
View directory record Official record
Conditions
Chronic Non-malignant Pain, Chronic Pain, Pain, Back, Pain, Leg
Interventions
Medtronic SynchroMed™ II infusion system, Preservative-free morphine sulfate (PFMS)
Device · Drug
Lead sponsor
MedtronicNeuro
Industry
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
16
States / cities
Anchorage, Alaska • Carlsbad, California • Napa, California + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain

NCT01452529
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Hydrocodone bitartrate q24h film-coated tablets, Placebo to match hydrocodone bitartrate q24h tablets
Drug
Lead sponsor
Purdue Pharma LP
Industry
Eligibility
18 Years and older
Enrollment
905 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
102
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 83 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 28, 2026, 3:40 AM EDT
Recruiting Phase 1 Interventional

Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain

NCT07122453
View directory record Official record
Conditions
Lower Back Pain
Interventions
CNTX-3001, Placebo
Drug
Lead sponsor
Centrexion Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Napa, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Hippocampal Stimulation in Chronic Low Back Pain

NCT04888494
View directory record Official record
Conditions
Chronic Pain, Back Pain, Pain
Interventions
Transcranial Magnetic Stimulation, Sham rTMS
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 28, 2026, 3:40 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Mechanistic Evaluation of Polypharmacy Effects for Pain

NCT07846020
View directory record Official record
Conditions
Chronic Lower Back Pain (CLBP)
Interventions
Within-subject test of blinded study medications (Placebo, Hydromorphone, Gabapentin)
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Trial of Inserting Prevalence Information Into Lumbar Spine Imaging Reports

NCT02015455
View directory record Official record
Conditions
Low Back Pain, Back Pain, Lumbar Pain, Backache
Interventions
Epidemiologic benchmarks included in lumbar imaging reports
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
250,401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
Oakland, California • Detroit, Michigan • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 28, 2026, 3:40 AM EDT
Recruiting Not applicable Interventional

Feasibility of Identifying Brain Mechanisms of Qigong and Behavioral Outcomes After Qigong Practice in People With Chronic Low Back Pain

NCT04164225
View directory record Official record
Conditions
Low Back Pain
Interventions
Qigong Exercise, P.Volve Exercises
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

The Efficacy of the Kyrobak for Chronic Low Back Pain (LBP-2)

NCT02155283
View directory record Official record
Conditions
Low Back Pain
Interventions
Continuous Passive Motion
Device
Lead sponsor
Radiancy
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2015 · Synced Oct 28, 2026, 3:40 AM EDT
Terminated Not applicable Interventional

FLO for Discogenic Pain

NCT03644251
View directory record Official record
Conditions
Discogenic Back Pain
Interventions
amniotic and umbilical cord matrix
Other
Lead sponsor
BioTissue Holdings, Inc
Industry
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2019 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain

NCT06814470
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Virtual reality guided imagery acupuncture treatment (VRGAIT), Virtual reality guided imagery acupuncture treatment control
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 3 Interventional Results available

Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Experienced Subjects

NCT01675167
View directory record Official record
Conditions
Low Back Pain
Interventions
Buprenorphine, Placebo
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years and older
Enrollment
815 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
66
States / cities
Birmingham, Alabama • Haleyville, Alabama • Mobile, Alabama + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Oct 28, 2026, 3:40 AM EDT
Not listed Phase 4 Interventional

Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain

NCT00445133
View directory record Official record
Conditions
Back Pain, Neck Pain, Sleep Initiation and Maintenance Disorders
Interventions
Magnetic Sleep Pad
Device
Lead sponsor
Weintraub, Michael I., MD, FACP, FAAN
Individual
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Briarcliff Manor, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2007 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 2 Interventional

A Study to Evaluate the Safety and Tolerability of Arbaclofen Placarbil (XP19986) in Subjects With Acute Back Spasms

NCT00817986
View directory record Official record
Conditions
Back Pain
Interventions
Arbaclofen placarbil, 20 mg, Placebo, Arbaclofen placarbil, 30 mg, Arbaclofen placarbil, 40 mg
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
20
States / cities
Litchfield Park, Arizona • Anaheim, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 4 Interventional

Topical Lidocaine Patch in Low Back Pain

NCT00904540
View directory record Official record
Conditions
Acute and Chronic Non-radicular LBP
Interventions
Lidoderm®
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
7
States / cities
Phoenix, Arizona • Mill Valley, California • Weston, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 2 Interventional Results available

Neurosteroids as Novel Therapeutic Agents for Chronic Pain in OEF/OIF Veterans

NCT01898013
View directory record Official record
Conditions
Lower Back Pain
Interventions
Pregnenolone, Placebo
Drug
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 1Phase 2 Interventional

Integrative Breathwork Intervention for Chronic Pain

NCT06546956
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Integrative Breathwork Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

CAFE Study - Cancer Patient Fracture Evaluation

NCT00211237
View directory record Official record
Conditions
Cancer, Spinal Fractures
Interventions
Balloon Kyphoplasty, Non Surgical Management
Device · Other
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
9
States / cities
Escondido, California • Boulder, Colorado • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.

NCT04704375
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Bio Electro-Magnetic Regulation (BEMER) Therapy, OMT (osteopathic manipulative treatment), Light touch
Device · Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 28, 2026, 3:40 AM EDT
Completed Phase 3 Interventional Results available

Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets

NCT01922739
View directory record Official record
Conditions
Low Back Pain
Interventions
Hydrocodone ER, Placebo
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
61
States / cities
Birmingham, Alabama • Mobile, Alabama • Montgomery, Alabama + 54 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 28, 2026, 3:40 AM EDT