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ClinicalTrials.gov public records Last synced Oct 29, 2026, 12:02 AM EDT

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Showing 361–384 of 1,088 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional Results available

Phase 2 Chronic Low Back Pain Study

NCT01364922
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
hydrocodone/acetaminophen extended release, Placebo
Drug
Lead sponsor
AbbVie (prior sponsor, Abbott)
Industry
Eligibility
18 Years to 75 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
17
States / cities
Tucson, Arizona • Anaheim, California • Burbank, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

PNE Effectiveness Cluster Trial

NCT03168165
View directory record Official record
Conditions
Neck Pain, Low Back Pain, Chronic Pain
Interventions
Pain neuroscience education training
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 75 Years
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
41
States / cities
Birmingham, Alabama • Helena, Alabama • Hoover, Alabama + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 29, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional

COMPARATIVE EFFECTIVENESS OF EXERCISE, COGNITIVE BEHAVIOURAL THERAPY, AND THEIR COMBINATION FOR PEOPLE WITH CHRONIC MUSCULOSKELETAL PAIN AND POOR SLEEP: SLEEPFIT TRIAL

NCT07532070
View directory record Official record
Conditions
Osteo Arthritis Knee and Hip, Low Back Pain, Insomnia
Interventions
Aerobic physical activity, CBT-I, Combined aerobic physical activity and CBT-I
Behavioral
Lead sponsor
University of Sydney
Other
Eligibility
18 Years and older
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
San Antonio, Nevada • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional Results available

Effect of Nitrous Oxide in Treating Neuropathic Pain: A Study in Chronic Low Back Pain Patients

NCT01172600
View directory record Official record
Conditions
Low Back Pain, Radiating Pain
Interventions
Entonox, Oxygen
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Phase 4 Interventional Results available

Orphenadrine and Methocarbamol for LBP

NCT02665286
View directory record Official record
Conditions
Low Back Pain
Interventions
Orphenadrine, Methocarbamol, Naproxen, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 29, 2026, 12:02 AM EDT
Recruiting Phase 1 Interventional

Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain

NCT05909709
View directory record Official record
Conditions
Facet Joints; Degeneration, Back Pain, Facet Joint Pain
Interventions
Alocyte low dose, Alocyte medium dose, Alocyte high dose
Drug
Lead sponsor
Alimorad Farshchian
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
North Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 29, 2026, 12:02 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

The Use of Real Time Ultrasound Feedback in Teaching Abdominal Hollowing Exercises

NCT00005771
View directory record Official record
Conditions
Low Back Pain
Interventions
Visual utrasound feedback, Abdominal Hollowing Exercise
Device · Procedure
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 29, 2026, 12:02 AM EDT
Withdrawn Phase 4 Interventional

Adjunctive 5% Lidocaine Patches for Acute Non-radicular Low Back Pain in Emergency Department Patients

NCT03301766
View directory record Official record
Conditions
Low Back Pain
Interventions
lidocaine 5% patch, standard therapy, Non-medicated patch
Drug
Lead sponsor
Cook County Health
Government
Eligibility
24 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional Results available

Postoperative Telehealth Mindfulness Intervention After Spine Surgery

NCT04648683
View directory record Official record
Conditions
Chronic Low-back Pain, Postsurgical Pain, Opioid Use, Lumbar Spine Surgery
Interventions
Individual telehealth mindfulness, Group telehealth mindfulness
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional Results available

Restorative Exercise for Strength Training and Operational Resilience (RESTORE) for Chronic or Recurrent Low Back Pain

NCT02132910
View directory record Official record
Conditions
Lower Back Pain
Interventions
RESTORE Intervention
Other
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 68 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Safety and Efficacy of the BTL-043 Device in Alleviating Back Pain

NCT07661082
View directory record Official record
Conditions
Back Pain, Chronic Back Pain
Interventions
Device: Treatment with BTL-043
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Scottsdale, Arizona • Denver, Colorado • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Trigger Point Dry Needling vs Trigger Point Dry Needling With Intramuscular Electrical Stimulation

NCT03539588
View directory record Official record
Conditions
Sub-acute and Chronic Low Back Pain
Interventions
trigger point dry needling, Electrical Stimulation
Device
Lead sponsor
William Beaumont Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Oct 29, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strain-Counterstrain Treatment of Piriformis Pain

NCT05023005
View directory record Official record
Conditions
Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
Interventions
Strain-Counterstrain treatment of piriformis muscle
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 29, 2026, 12:02 AM EDT
Completed No phase listed Observational

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

NCT06653920
View directory record Official record
Conditions
Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions
Chiropractic, Exercise, Cryotherapy, Spinalator
Other · Device
Lead sponsor
Leach Chiropractic Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Standing Trunk Extension and Spinal Height in Low Back Pain

NCT03785457
View directory record Official record
Conditions
Low Back Pain
Interventions
Repetitive Trunk Extension, Sustained Trunk Extension
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Fredericksburg, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)

NCT00580294
View directory record Official record
Conditions
Pain
Interventions
Oxymorphone
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

The Effect of Combining Spinal Manipulation and Dry Needling in Individuals With Low Back Pain

NCT05802901
View directory record Official record
Conditions
Non-specific Low Back Pain
Interventions
Spinal manipulation, Dry needling, Spinal manipulation and dry needling
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain

NCT00487266
View directory record Official record
Conditions
Low Back Pain
Interventions
Acupuncture
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 29, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional

Perspectives on Spinal Manipulative Therapy for Low Back Pain

NCT06590116
View directory record Official record
Conditions
Low Back Pain
Interventions
Physical therapy, Physical therapist provider
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 29, 2026, 12:02 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Sub-Sensory Intraspinal Neurostimulation Therapy

NCT01976598
View directory record Official record
Conditions
Back Pain, Back Pain With Radiation, Pain in Leg, Unspecified
Interventions
Sub-Sensory Stimulation
Other
Lead sponsor
Algos Clinical Development Thomas L. Yearwood, MD, PhD
Other
Eligibility
22 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pascagoula, Mississippi
Source: ClinicalTrials.gov public record
Updated Jan 19, 2015 · Synced Oct 29, 2026, 12:02 AM EDT
Terminated Not applicable Interventional

Osteopathic Manipulative Treatment and Postural Control: Systems Engineering Approach

NCT02261233
View directory record Official record
Conditions
Low Back Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 4, 2019 · Synced Oct 29, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Individualized Chiropractic and Integrative Care for Low Back Pain

NCT00567333
View directory record Official record
Conditions
Sub-Acute and Chronic Low Back Pain
Interventions
Chiropractic care, Multidisciplinary, integrative care
Other
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 29, 2026, 12:02 AM EDT
Not listed Not applicable Interventional

Cost Effectiveness and Clinical Utility of Cell Saver Use for Two to Three Level Lumbar Fusions

NCT01453309
View directory record Official record
Conditions
Low Back Pain Unresponsive to Non-surgical Care
Interventions
Cell Saver, No Cell Saver
Procedure
Lead sponsor
Norton Leatherman Spine Center
Other
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 17, 2011 · Synced Oct 29, 2026, 12:02 AM EDT
Terminated Not applicable Interventional Results available

KAVIAR Study - Kyphoplasty And Vertebroplasty In the Augmentation and Restoration of Vertebral Body Compression Fractures

NCT00323609
View directory record Official record
Conditions
Vertebral Body Compression Fractures
Interventions
Vertebroplasty, Kyphoplasty
Procedure
Lead sponsor
Medtronic Spine LLC
Industry
Eligibility
21 Years and older
Enrollment
404 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
25
States / cities
Scottsdale, Arizona • San Jose, California • Torrance, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 29, 2026, 12:02 AM EDT