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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:23 PM EDT

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Showing 145–168 of 1,088 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 4 Interventional

A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain

NCT00904020
View directory record Official record
Conditions
Postherpetic Neuralgia, Diabetic Neuropathy, Low Back Pain
Interventions
Lidoderm
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
11
States / cities
Birmingham, Alabama • Phoenix, Arizona • Plantation, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy?

NCT00826124
View directory record Official record
Conditions
Lumbosacral Radiculopathy
Interventions
Epidural steroid injection, Magnetic Resonance Imaging (MRI)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2011 · Synced Oct 27, 2026, 1:23 PM EDT
Terminated Not applicable Interventional

Effect of Hamstring Stretching and Neural Mobilization on Range of Motion and Low Back Pain

NCT01483573
View directory record Official record
Conditions
Low Back Pain
Interventions
neural mobilization, straight leg raise
Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 27, 2026, 1:23 PM EDT
Terminated No phase listed Observational

Bone Graft Materials Observational Registry

NCT00974623
View directory record Official record
Conditions
Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis, Spinal Deformity, Cervical Myelopathy, Failed Back Surgery Syndrome, Spinal Cord Neoplasms
Interventions
Bone graft substitute, autograft or allograft
Device
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
329 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
12
States / cities
San Francisco, California • Atlanta, Georgia • Carrollton, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 27, 2026, 1:23 PM EDT
Terminated Not applicable Interventional Results available

MOTIVATE: Moving to Improve Outcomes for Older Adults

NCT03914469
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Behavioral Intervention Group
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 14, 2025 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 2 Interventional

Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain

NCT01043263
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
EN3324 (axomadol), Placebo
Drug
Lead sponsor
Grünenthal GmbH
Industry
Eligibility
18 Years and older
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
59
States / cities
Phoenix, Arizona • Tucson, Arizona • Tuscon, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2015 · Synced Oct 27, 2026, 1:23 PM EDT
Recruiting Not applicable Interventional

Investigating Medical Massage Therapy for Patients With Sub-Acute Lower Back Pain

NCT07615816
View directory record Official record
Conditions
Lower Back Pain, Subacute Lower Back Pain, Medical Massage Therapy
Interventions
Medical Massage Therapy, Provider Directed Care
Procedure · Other
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Joint Base Lewis McChord, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 4 Interventional

Self System Therapy and Chronic Low Back Pain Trial

NCT00672880
View directory record Official record
Conditions
Low Back Pain, Depression
Interventions
Self-System Therapy, Education, Standard Care
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 100 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 27, 2026, 1:23 PM EDT
Terminated Phase 4 Interventional Results available

Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy

NCT00619983
View directory record Official record
Conditions
Diabetic Neuropathic Pain, Chronic Low Back Pain
Interventions
donepezil, duloxetine, donepezil 2.5 mg and duloxetine 30mg, placebo, gabapentin
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Evaluation the Impact of the "Pas" Technique Versus the "Standard" Technique on Radiation Exposure

NCT06918197
View directory record Official record
Conditions
Spine, Fluoroscopy for Spine Surgery, Back Pain, Sacroiliac Joint
Interventions
PAS Technique, Standard Technique
Procedure
Lead sponsor
Orthospine Advance Health, Inc.
Other
Eligibility
19 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Merced, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Sustained Acoustic Medicine for Chronic Low Back Pain Secondary to Herniated Nucleus Pulposus or Other Conditions

NCT02609854
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP), Intervertebral Disc Displacement
Interventions
Sustained Acoustic Medicine (SAM), Sham Device
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Dryden, New York • Chapel Hill, North Carolina • Ogden, Utah
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 1 Interventional

Allogeneic BM-MSCs in Patients with Lumbar Facet Arthropathy

NCT04410731
View directory record Official record
Conditions
Facet-Mediated Low Back Pain
Interventions
Single bilateral intra-articular injection of allogeneic BM-MSCs for lumbar facet joint arthropathy
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 3 Interventional Results available

Buprenorphine (CAM2038) in Subjects With a Recent History of Moderate to Severe Chronic Low Back Pain

NCT02946073
View directory record Official record
Conditions
Chronic Lower Back Pain, Chronic Pain
Interventions
buprenorphine, Placebo
Drug · Other
Lead sponsor
Braeburn Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
1,053 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
69
States / cities
Birmingham, Alabama • Hamilton, Alabama • Vestavia Hills, Alabama + 54 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 27, 2026, 1:23 PM EDT
Withdrawn Phase 4 Interventional

Adjunctive 5% Lidocaine Patches for Acute Non-radicular Low Back Pain in Emergency Department Patients

NCT03301766
View directory record Official record
Conditions
Low Back Pain
Interventions
lidocaine 5% patch, standard therapy, Non-medicated patch
Drug
Lead sponsor
Cook County Health
Government
Eligibility
24 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 27, 2026, 1:23 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Connective Tissue Motion Measure 2

NCT01784094
View directory record Official record
Conditions
Low Back Pain, Musculoskeletal Pain
Interventions
StromaGlide
Device
Lead sponsor
Stromatec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 30, 2014 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Battlefield Acupuncture for the Treatment of Low Back Pain in the Emergency Department

NCT02399969
View directory record Official record
Conditions
Low Back Pain
Interventions
Battlefield Acupuncture
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2016 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 2 Interventional Results available

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain

NCT04874636
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
LY3556050, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
33
States / cities
Birmingham, Alabama • Chandler, Arizona • Glendale, Arizona + 27 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 3 Interventional Results available

Phase 3 Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Low Back Pain

NCT01081912
View directory record Official record
Conditions
Back Pain Lower Back Chronic
Interventions
Placebo, Hydrocodone bitartrate
Drug
Lead sponsor
Zogenix, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
510 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
51
States / cities
Phoenix, Arizona • Jonesboro, Arkansas • Anaheim, California + 47 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Oct 27, 2026, 1:23 PM EDT
Terminated Phase 4 Interventional Results available

Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy

NCT03801356
View directory record Official record
Conditions
Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
Interventions
Selective Nerve Root Block
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Not applicable Interventional

Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes

NCT06360341
View directory record Official record
Conditions
Low Back Pain, Mechanical, Acute Pain
Interventions
Emergency Department Digital Pain Self-Management Intervention (EDPSI), Routine Discharge Care
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 27, 2025 · Synced Oct 27, 2026, 1:23 PM EDT
Withdrawn No phase listed Observational

Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials

NCT05540756
View directory record Official record
Conditions
Pain, Chronic, Lumbar Radiculopathy, SCS
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Timeline
2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2023 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lumbar Injectrode Feasibility Evaluation

NCT06206356
View directory record Official record
Conditions
Chronic Pain, Lower Back Pain Chronic
Interventions
PNS Injectrode F1
Device
Lead sponsor
Neuronoff, Inc
Industry
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 27, 2026, 1:23 PM EDT
Not listed Phase 1Phase 2 Interventional

The Effects of Short Arc Banding

NCT00885001
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Short Arc Banding
Procedure
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2009 · Synced Oct 27, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Low Intensity Ultrasound Therapy for Upper Back Pain Relief

NCT02135094
View directory record Official record
Conditions
Muscle Spasm
Interventions
Active ultrasound therapy device, Placebo ultrasound therapy device
Device
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Trumbull, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 27, 2026, 1:23 PM EDT