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ClinicalTrials.gov public records Last synced Oct 27, 2026, 4:01 PM EDT

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Showing 193–216 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Backache Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome

NCT03444168
View directory record Official record
Conditions
Chronic Pain
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
22 Years to 70 Years
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Completed No phase listed Observational

Clinical Correlates of Pressure Pain Thresholds in Back and Leg Pain

NCT06653920
View directory record Official record
Conditions
Segmental Dysfunction of the Lumbar Spine, Back Pain, Leg Pain
Interventions
Chiropractic, Exercise, Cryotherapy, Spinalator
Other · Device
Lead sponsor
Leach Chiropractic Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Accessible Acupuncture for the Warrior With Acute Low Back Pain

NCT04236908
View directory record Official record
Conditions
Acupuncture, Low Back Pain
Interventions
NSAIDS, Battlefield Acupuncture, GV26 with manual tonification
Drug · Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years and older
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 2 Interventional

Effect of Yoga Vs. Stretching on Chronic Back Pain

NCT00447668
View directory record Official record
Conditions
Chronic Non-specific Low Back Pain
Interventions
Yoga, Exercise, Self-care book recommendations
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 64 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 2 Interventional

Psychosocial Treatment for Acute Low Back Pain

NCT00000418
View directory record Official record
Conditions
Acute Low Back Pain
Interventions
Psychosocial intervention
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1977 – 2001
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 6, 2013 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 3 Interventional Results available

Long-Term Safety and Tolerability Study of NKTR-181 in Subjects With Chronic Low Back Pain or Chronic Non-Cancer Pain

NCT02367820
View directory record Official record
Conditions
Low Back Pain, Chronic Pain
Interventions
NKTR-181 BID tablets
Drug
Lead sponsor
Nektar Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
638 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
56
States / cities
Saraland, Alabama • Phoenix, Arizona • Tempe, Arizona + 50 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 27, 2026, 4:01 PM EDT
Completed No phase listed Observational

Examining the Effects of Dorsal Column Stimulation on Pain From Lumbar Spinal Stenosis Related to Epidural Lipomatosis.

NCT05811143
View directory record Official record
Conditions
Lipomatosis, Low Back Pain
Interventions
Spinal Cord Stimulator
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Recruiting Phase 3 Interventional

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

NCT06027099
View directory record Official record
Conditions
Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
Interventions
Tizanidine, MI-Opioid Taper, Placebo, Enhanced Usual Care
Drug · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Stanford, California • Kansas City, Kansas • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

PRECISION Pain Research Registry

NCT04853732
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Not listed
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
21 Years to 79 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 4 Interventional Results available

Placebo In Chronic Back Pain (Phase 2)

NCT02986334
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Naproxen, Omeprazole, Placebo
Drug
Lead sponsor
Apkar Apkarian
Other
Eligibility
18 Years to 75 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

A Pilot Trial of IV Pamidronate for Low Back Pain

NCT01210599
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Pamidronate
Drug
Lead sponsor
Pappagallo, Marco, M.D.
Individual
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2010 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 2 Interventional Results available

Evaluating the Role of Neuroinflammation in Low Back Pain

NCT03106740
View directory record Official record
Conditions
Low Back Pain, Back Pain With Radiation, Back Pain Without Radiation, Back Pain Lower Back Chronic, Back Ache, Pain, Chronic
Interventions
Minocycline Hydrochloride 100mg Capsule, Magnetic Resonance-Positron Emission Tomography Imaging, Placebo Capsule
Drug · Diagnostic Test · Other
Lead sponsor
Marco Loggia
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Worksite Exercise Interventions for Low Back Injury Prevention in Firefighters

NCT02362243
View directory record Official record
Conditions
Low Back Pain
Interventions
Experimental Intervention, Placebo Comparator
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Internet-based Behavioral Pain Management

NCT01918189
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
behavioral pain self-management intervention Pain EASE
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 27, 2026, 4:01 PM EDT
Active, not recruiting Not applicable Interventional

SMART Stepped Care Management for Low Back Pain in the Military Health System

NCT04172038
View directory record Official record
Conditions
Low Back Pain, Chronic Pain, Military Personnel, Veterans
Interventions
Physical Therapy, Move 2 Health (M2H), MORE Mindfulness
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Schofield Barracks, Hawaii • San Antonio, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 27, 2026, 4:01 PM EDT
Terminated Phase 2 Interventional

A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo

NCT01771471
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
NuQu, Placebo
Biological · Other
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
10
States / cities
Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

NCT00000409
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 27, 2026, 4:01 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional

PRP Versus NP Injections for Chronic Discogenic Low Back Pain

NCT07895225
View directory record Official record
Conditions
Discogenic Low Back Pain
Interventions
Platelet-Rich Plasma (PRP) Injection, Nucleus Pulposus (NP) Injection
Biological
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 100 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Recruiting No phase listed Observational

Examination of Nociscan Impact on Low Back Pain Surgical Outcomes

NCT06661850
View directory record Official record
Conditions
Low Back Pain
Interventions
Fusion or TDR determined by investigator.
Procedure
Lead sponsor
Aclarion
Industry
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
10
States / cities
Phoenix, Arizona • Beverly Hills, California • La Jolla, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain

NCT05022121
View directory record Official record
Conditions
Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic, Intervertebral Disc Displacement
Interventions
Supported Biopsychosocial Self-Management (SBSM), Medical Care
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Minneapolis, Minnesota • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 27, 2026, 4:01 PM EDT
Recruiting Not applicable Interventional

AuriculoTherapy NeuroImaging

NCT06825390
View directory record Official record
Conditions
Low Back Pain, Chronic Low-back Pain, Back Pain, Low, Lumbar Disc Disease, Lumbar Discogenic Pain, Lumbar Pain Syndrome, Lumbar Post-Laminectomy Syndrome, Back Pain Lower Back Chronic, Back Pain Without Radiation, Pain;Back Low;Chronic
Interventions
Cryo-auriculotherapy, Sham auriculotherapy, Experimental auricular stimulation
Device · Other
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional

Yoga vs. Education for Veterans With Chronic Low Back Pain

NCT02224183
View directory record Official record
Conditions
Recurrent Low Back Pain
Interventions
Education, Yoga
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced Oct 27, 2026, 4:01 PM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the TransDiscal System Versus Medical Management in Treating Chronic Discogenic Low Back Pain

NCT01263054
View directory record Official record
Conditions
Back Pain
Interventions
TransDiscal System, Medical Management
Device · Other
Lead sponsor
Halyard Health
Industry
Eligibility
21 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
9
States / cities
Washington D.C., District of Columbia • Orlando, Florida • Bloomington, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Oct 27, 2026, 4:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain

NCT05860205
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation
Behavioral · Other
Lead sponsor
Kailea Manning
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 27, 2026, 4:01 PM EDT