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ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:51 PM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers

Preserving Muscle Mass and Function in Bedridden Older Adults

NCT01846130
Conditions
Bed Rest
Interventions
Leucine, Exercise, Whey protein
Dietary Supplement · Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
60 Years to 80 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Galveston, Texas
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Evaluation of AN777 on Elderly Subjects During Bed Rest and Recovery

NCT00945581
Conditions
Aged
Interventions
Experimental Nutritional Powder Formula, Placebo comparator
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
60 Years to 79 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Type 2 Diabetes, Muscle Atrophy, Aging, Sedentary Behavior, Pre-diabetes
Interventions
Bed rest
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Music Therapy, Preterm Premature Rupture of Membrane (PPROM)
Interventions
Music Therapy Intervention
Behavioral
Lead sponsor
Christina Chianis Reed
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention

NCT07698483
Conditions
Preterm Birth, Activity Restriction, Bed Rest, Low-Value Care
Interventions
Multicomponent deimplementation strategy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
237 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Relaxation Interventions for Pre-term Mothers on Hospitalized Bed-Rest

NCT03419065
Conditions
High Risk Pregnancy
Interventions
Relaxation Intervention
Behavioral
Lead sponsor
Towson University
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Towson, Maryland
Conditions
Preterm Premature Rupture of the Membranes, Physical Activity
Interventions
Moderate Activity
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
San Diego, California
Conditions
Pregnancy, Pre-term Premature Rupture of Membranes
Interventions
Bed Rest, Activity
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Elmhurst, New York • New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Identifying Therapeutic Targets of Accelerated Sarcopenia

NCT03118050
Conditions
Sarcopenia, Diabetes Mellitus, Aging
Interventions
Resistance exercise training, Bed rest, Intensive physical therapy
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
60 Years to 85 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Study Focuses on Bed Rest and Deconditioning in Hospital Inpatients
Interventions
Provision of recliner chairs and encouragement to get out of bed
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 100 Years
Enrollment
6,089 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Healthy
Interventions
ONS without AN777, ONS containing AN777
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
60 Years to 79 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Little Rock, Arkansas • Orlando, Florida • College Station, Texas
Conditions
Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise, Pre-diabetes
Interventions
Bed Rest Intervention, Exercise Program
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Salsalate on Bed Rest-Induced Vascular Dysfunction

NCT00553995
Conditions
Insulin Resistance
Interventions
salsalate, Placebo
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Space Flight Simulation to Study Effects of Micro-gravity Through Bed Rest

NCT00891449
Conditions
Weightlessness
Interventions
Not listed
Lead sponsor
National Aeronautics and Space Administration (NASA)
Federal
Eligibility
24 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Heart Failure; With Decompensation
Interventions
Medtronic ICDs, CRT-Ds, and CRT-Ps
Device
Lead sponsor
Charles Porter, MD
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Kansas City, Kansas
Terminated No phase listed Observational Accepts healthy volunteers

Effect of Bedrest With and Without Exercise on the Heart

NCT00598494
Conditions
Bedrest
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia, Syncope, Ventricular Tachycardia
Interventions
Early mobilization
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Portland, Oregon
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Two Days of Bedrest on Insulin Resistance in Type 2 Diabetics

NCT00508599
Conditions
Type 2 Diabetes, Insulin Resistance
Interventions
Study 2 (48 hours of complete bed rest)
Other
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Albuquerque, New Mexico