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ClinicalTrials.gov public records Last synced Nov 3, 2026, 5:01 AM EST

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Showing 97–120 of 162 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Bedsores Clear all
Completed Not applicable Interventional Results available

Limb Health and Socket Pressure in Response to Powered Ankle Protheses

NCT05112679
View directory record Official record
Conditions
Pressure Ulcer, Ankle, Prosthesis User, Prosthesis Durability, Mobility Limitation, Skin Wound, Amputation; Traumatic, Foot, Amputation, Limb Deficiencies
Interventions
PROPRIO FOOT® by Ossur & Empower ankle by Ottobock
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Nov 3, 2026, 5:01 AM EST
Recruiting Phase 4 Interventional

NPWTi on Closure of Chronic Pressure Sores

NCT05598398
View directory record Official record
Conditions
Pressure Sore
Interventions
V.A.C.Ulta™ Negative Pressure Wound Therapy System, Standard of Care (Wet-to-dry dressings)
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Nov 3, 2026, 5:01 AM EST
Recruiting Not applicable Interventional

R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment

NCT05425810
View directory record Official record
Conditions
Lower Limb Amputation Below Knee (Injury)
Interventions
Apply ENABLE sensing pad, Insert small pads at pressure tolerant locations
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 99 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Nov 3, 2026, 5:01 AM EST
Completed Phase 3 Interventional

Pressure Ulcer Prevention: Turning for Ulcer Reduction

NCT00665535
View directory record Official record
Conditions
Pressure Ulcers
Interventions
Turning or repositioning schedule
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
967 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
19
States / cities
Glendale, Arizona • Loma Linda, California • Los Angeles, California + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2012 · Synced Nov 3, 2026, 5:01 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Pressure Injury Prevention in AE and PFC

NCT03924622
View directory record Official record
Conditions
Pressure Injury, Military Activity
Interventions
Mepilex, LiquiCell
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional

Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.

NCT04776967
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury, Pressure Injury, Ear Barotrauma
Interventions
Hyperbaric Compression Profile
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2021 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional Results available

Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries

NCT03283787
View directory record Official record
Conditions
Pressure Ulcers Stage III, Pressure Ulcer, Stage IV, Pressure Ulcer
Interventions
MicroMatrix® and Cytal™ Wound Matrix 2-Layer, MicroMatrix® and Cytal™ Wound Matrix 2-Layer plus NPWT, Negative Pressure Wound Therapy
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional Results available

A Pilot Study to Assess the DynaSense System

NCT02005692
View directory record Official record
Conditions
Pressure Ulcers
Interventions
DynaSense sensor
Device
Lead sponsor
Leaf Healthcare, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2014 · Synced Nov 3, 2026, 5:01 AM EST
Enrolling by invitation Not applicable Interventional

Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds

NCT07653165
View directory record Official record
Conditions
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries, Surgical Wounds
Interventions
Motion NPWT
Device
Lead sponsor
West Boca Center for Wound Healing
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Coconut Creek, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Nov 3, 2026, 5:01 AM EST
Terminated Phase 4 Interventional Results available

Study of SANTYL® vs Hydrogel (SoloSite®) for Pressure Ulcers

NCT02718625
View directory record Official record
Conditions
Pressure Ulcer
Interventions
Santyl, SoloSite®
Biological
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lee's Summit, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Colonoscopy in the Prone Position for Patients With BMI Greater Than 30

NCT03337217
View directory record Official record
Conditions
Obesity
Interventions
Position during colonoscopy
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 90 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Nov 3, 2026, 5:01 AM EST
Withdrawn No phase listed Observational

WEMR With Clinical Decision Support for All Wounds

NCT02055599
View directory record Official record
Conditions
Chronic Wounds
Interventions
Not listed
Lead sponsor
Winthrop University Hospital
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional

MicroMatrix® Flex in Tunneling Wounds

NCT06629506
View directory record Official record
Conditions
Pressure Injury, Venous Ulcer, Necrotizing Soft Tissue Infection, Diabetic Ulcers, Draining Wound
Interventions
MicroMatrix® Flex, MicroMatrix® UBM Particulate, Cytal® Wound Matrix 2-Layer
Device
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Nov 3, 2026, 5:01 AM EST
Active, not recruiting No phase listed Observational

HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU

NCT07223515
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Not listed
Lead sponsor
Dynamic Medical Services dba Acesso Biologics
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Novi, Michigan • Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Nov 3, 2026, 5:01 AM EST
Terminated Not applicable Interventional

PuraPly® AM Plus the Standard of Care to Standard of Care Alone for the Management of Stage II-IV Pressure Ulcers.

NCT03502824
View directory record Official record
Conditions
Chronic Pressure Ulcers
Interventions
PuraPly® Antimicrobial Wound Matrix, SOC for Pressure Ulcers
Device · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Lake Success, New York • Mineola, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Nov 3, 2026, 5:01 AM EST
Not listed Not applicable Interventional

Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring

NCT05311124
View directory record Official record
Conditions
Wound Care, Pressure Ulcer, Venous Ulcer, Surgical Wound, Trauma Wounds, Draining Wound
Interventions
Integra Dermal Regeneration template (IDRT)
Device
Lead sponsor
Joshua Choo
Other
Eligibility
55 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Nov 3, 2026, 5:01 AM EST
Recruiting Phase 4 Interventional

Study Title: A Multicenter, Prospective, Modified Platform Trial Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers.

NCT07665268
View directory record Official record
Conditions
Skin Ulcer, Pressure Ulcer (PU), Pressure Ulcer of Skin, Pressure Sore, Chronic Ulcer, Pressure Wound
Interventions
Activate™ Matrix + SOC, AmnioDefend™ FT Matrix + SOC, Palisade™ DM Matrix + SOC, Sentry™ SL Matrix + SOC, Shelter™ DM Matrix + SOC
Other
Lead sponsor
Sequence LifeScience, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
North Royalton, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Nov 3, 2026, 5:01 AM EST
Completed Phase 2 Interventional Results available

Study of Thymosin Beta 4 in Patients With Pressure Ulcers

NCT00382174
View directory record Official record
Conditions
Pressure Ulcers
Interventions
Placebo, Thymosin Beta 4
Drug
Lead sponsor
RegeneRx Biopharmaceuticals, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Montgomery, Alabama • Beverly Hills, California • Long Beach, California + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2010 · Synced Nov 3, 2026, 5:01 AM EST
Recruiting Not applicable Interventional

Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)

NCT05458947
View directory record Official record
Conditions
Spinal Cord Injuries, Pressure Injuries
Interventions
pulsed wound irrigation (PWI), electrical stimulation (ES), electrical stimulation (ES) and pulsed wound irrigation (PWI)
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Nov 3, 2026, 5:01 AM EST
Completed No phase listed Observational

A Test of the Investigational SEM Scanner

NCT01965444
View directory record Official record
Conditions
Pressure Ulcers
Interventions
Not listed
Lead sponsor
Bruin Biometrics, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 24, 2013 · Synced Nov 3, 2026, 5:01 AM EST
Completed Phase 4 Interventional Results available

Pressure Ulcer Healing With Microcyn

NCT02001558
View directory record Official record
Conditions
Pressure Ulcer, Spinal Cord Injuries
Interventions
Microcyn, Sterile saline
Drug · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Nov 3, 2026, 5:01 AM EST
Not listed No phase listed Observational Accepts healthy volunteers

The Analysis of Skin Temperature by Long Wave Infrared Imaging to Determine Its Effectiveness as a Predictor of Tissue Injury

NCT00664235
View directory record Official record
Conditions
Pressure Ulcers, Tissue Injury
Interventions
Not listed
Lead sponsor
Trillennium Medical Imaging, Inc.
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2008 · Synced Nov 3, 2026, 5:01 AM EST
Completed Not applicable Interventional Results available

An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions

NCT00178126
View directory record Official record
Conditions
Pressure Ulcer
Interventions
Skin Protection Wheelchair Seat Cushion, Segmented Foam Wheelchair Seat Cushion
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
232 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Nov 3, 2026, 5:01 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Silk-Like Fabric for the Prevention of Pressure Sores in a Long Term Care Setting

NCT01355666
View directory record Official record
Conditions
Pressure Ulcers
Interventions
DermaTherapy® Linen and underpads.
Device
Lead sponsor
Precision Fabrics Group, Inc.
Other
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2011 · Synced Nov 3, 2026, 5:01 AM EST