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ClinicalTrials.gov public records Last synced Oct 28, 2026, 3:27 PM EDT

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Showing 217–240 of 413 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Behavioral Addiction Clear all
Recruiting Not applicable Interventional

The Trans-Led Care Study

NCT06880705
View directory record Official record
Conditions
Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol), Human Immunodeficiency Virus (HIV)
Interventions
The TLC Program
Behavioral
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Combination Bupropion / Varenicline for Smoking Cessation in Male Smokers

NCT01806779
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Chantix, Zyban, Nicotine patches
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
4
States / cities
Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2016 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Modafinil vs Placebo for the Treatment of Methamphetamine Dependence

NCT00469508
View directory record Official record
Conditions
Methamphetamine Dependence
Interventions
Modafinil, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Hollywood, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Treatment of Cocaine Dependence With Lisdexamfetamine

NCT00958282
View directory record Official record
Conditions
Cocaine Dependence
Interventions
lisdexamfetamine/Behavior Therapy, placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2015 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray

NCT01136642
View directory record Official record
Conditions
Drug Addiction, Nicotine Dependence
Interventions
Nicotrol
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

First Face Training Evaluation in Tribal Communities

NCT05998005
View directory record Official record
Conditions
Mental Health, Substance-Related Disorders
Interventions
First Face Training Program
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
14 Years and older
Enrollment
554 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
9
States / cities
Bonners Ferry, Idaho • Lapwai, Idaho • Plummer, Idaho + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 28, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

NCT06103370
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders, Addiction, Opioid Use, Drug Use, Intravenous Drug Usage
Interventions
Peer-educator-based network
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Frederick, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^

NCT01227980
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Dependence, Alcoholism, Anxiety Disorder
Interventions
Pexacerfont, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 28, 2026, 3:27 PM EDT
Terminated Not applicable Interventional

The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3

NCT00142883
View directory record Official record
Conditions
Cocaine Abuse, Cocaine-Related Disorders
Interventions
Pregabalin, placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 8, 2015 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Addiction Housing Case Management for Homeless Veterans

NCT01346514
View directory record Official record
Conditions
Homelessness, Substance Abuse Disorders, Mental Disorders
Interventions
Intensive Addiction/Housing Case Management, Housing Support Group
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 1 Interventional

Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder

NCT00218725
View directory record Official record
Conditions
Suicide, Attempted, Substance-Related Disorders
Interventions
Cognitive Therapy, Enriched Care
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2015 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional

Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse Prevention

NCT04843046
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Cognitive Behavioral Therapy (CBT), Pioglitazone, Placebo
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effects of Sedatives on Tobacco Use Disorder Version 2

NCT05505630
View directory record Official record
Conditions
Tobacco Smoking
Interventions
Ketamine, Midazolam, Dexmedetomidine, Saline
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Vigabatrin for Treatment of Cocaine Dependence

NCT00611130
View directory record Official record
Conditions
Cocaine Dependence
Interventions
vigabatrin, placebo
Drug
Lead sponsor
Catalyst Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
11
States / cities
Little Rock, Arkansas • San Francisco, California • Torrance, California + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

The Effect of a Contingency Management Intervention on Substance Use

NCT00252512
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Contingency Management, Placebo
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 16, 2018 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dual Use Approach Bias Training for Nicotine Addiction

NCT05306158
View directory record Official record
Conditions
Tobacco Smoking, Electronic Cigarette Use, Substance Use
Interventions
CC+ECIG Condition, CC Condition, Sham Condition
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 28, 2026, 3:27 PM EDT
Completed No phase listed Observational

HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers

NCT00491335
View directory record Official record
Conditions
HIV Infections, AIDS, Lung Cancer, Tobacco Addiction, Drug Addiction
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
17 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional

Virtual Incentive Treatment for Alcohol

NCT06265506
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions
Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

An Open Label Study To Assess The Safety And Tolerability Of BEMA® Buprenorphine NX In Opioid Dependent Subjects

NCT01666119
View directory record Official record
Conditions
Opioid Dependence
Interventions
BEMA Buprenorphine NX films
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
10
States / cities
Birmingham, Alabama • Haleyville, Alabama • Jacksonville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Facilitated 5A's for Smoking Cessation in Primary Care

NCT02046408
View directory record Official record
Conditions
Nicotine Addiction, Smoking Cessation
Interventions
Computer Tablet
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
961 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors

NCT02000921
View directory record Official record
Conditions
Tobacco Addiction, Dual Tobacco Use
Interventions
VLNC cigarettes, Combusted Products, Non-combusted products, CN cigarettes
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Pilot Trial of Bupropion Versus Placebo for Methamphetamine Abuse in Adolescents

NCT00994448
View directory record Official record
Conditions
Adolescent Methamphetamine Abuse
Interventions
Bupropion SR 150mg tabs, Placebo tablets
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
14 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1

NCT00249496
View directory record Official record
Conditions
Alcohol Use, Drug Use, Risk Behavior, Sexual Behavior
Interventions
Contingency management, Employment Only
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Oct 28, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal

NCT00480441
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Dronabinol, BRENDA therapy, Placebo
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 55 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Oct 28, 2026, 3:27 PM EDT