Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 25, 2026, 9:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 413 matching trials from the live ClinicalTrials.gov search.
Conditions
Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester, Alcohol Use Complicating Pregnancy, Second Trimester, Alcohol Use Complicating Pregnancy, Third Trimester, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Alcohol Use Complicating Pregnancy, Childbirth, and the Puerperium, Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Drug Use Disorders, Drug Use Complicating Pregnancy, First Trimester, Drug Use Complicating Pregnancy, Second Trimester, Drug Use Complicating Pregnancy, Third Trimester, Drug Use Complicating Pregnancy, Unspecified Trimester, Drug Use Complicating Pregnancy, Childbirth, and the Puerperium, Maternal Drugs Affecting Fetus
Interventions
Parent-Child Assistance Program
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Tulsa, Oklahoma
Conditions
Food Addiction
Interventions
16-week Food Addiction Clinical Treatment (FACT) Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
25 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Cocaine Dependence, Cocaine Addiction, Cocaine Abuse, Substance Abuse
Interventions
Sitting, Running, Walking
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings

NCT02893514
Conditions
Addiction
Interventions
Screening Only (SO) condition, SUSIT Condition
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Opioid Dependence
Interventions
BEMA Buprenorphine NX films
Drug
Lead sponsor
BioDelivery Sciences International
Industry
Eligibility
18 Years to 65 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
10
States / cities
Birmingham, Alabama • Haleyville, Alabama • Jacksonville, Florida + 7 more
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

VK4-116 Phase I Study With Food-Effect

NCT06808932
Conditions
Opioid Dependence, Opioid Use Disorder (OUD)
Interventions
VK4-116, Placebo
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Overland Park, Kansas
Completed Phase 2 Interventional Results available

Genetic Effects on Dopamine Response to an Opiate

NCT01878006
Conditions
Polymorphism-Genetic, Pain, Addiction
Interventions
Morphine, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 55 Years · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Addiction, Substance Abuse, Cannabis Use Disorder, Cannabis Use, Cannabis Dependence, Cannabis Abuse
Interventions
Breathwork workshop
Behavioral
Lead sponsor
Elias Dakwar
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Cognitive Effects of Atomoxetine in Humans: Genetic Moderators

NCT01498549
Conditions
Addiction
Interventions
Atomoxetine, Sugar Pill
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Food Addiction
Interventions
telomere length measure
Diagnostic Test
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 70 Years
Enrollment
120 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Scottsbluff, Nebraska
Conditions
Opioid Use Disorder
Interventions
Youth Opioid Recovery Support (YORS)
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
13 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Addiction, Alcohol Use Disorder
Interventions
Take Control, Semaglutide
Behavioral · Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 110 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Intimate Partner Violence, Substance Abuse/Addiction, Child Maltreatment
Interventions
Fathers for Change, Parent Education
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St. Petersburg, Florida
Completed No phase listed Observational Accepts healthy volunteers

To Test a Payer/Treatment Agency Intervention to Increase Use of Buprenorphine

NCT01702142
Conditions
Addiction
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
17 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Terminated Phase 2 Interventional Accepts healthy volunteers

High Dose Bupropion for Smoking Cessation - Pilot Study

NCT03326128
Conditions
Smoking Cessation, Smoking, Tobacco, Smoking (Tobacco) Addiction, Cessation, Tobacco, Cigarette Smoking
Interventions
Bupropion Hydrochloride
Drug
Lead sponsor
University of Southern California
Other
Eligibility
21 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Training for Substance Use Disorders

NCT06870110
Conditions
Opioid Use Disorder
Interventions
Bias Modification Biofeedback
Device
Lead sponsor
Neurotype Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Eating Disorders, Bulimia
Interventions
Guided self-help cognitive behavioral therapy (CBT), Usual clinical care
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 50 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Middletown, Connecticut • Portland, Oregon
Conditions
Substance Use Disorders
Interventions
Technology Augmented Treatment for Screening, Brief Intervention, Referral, and Treatment (SBIRT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Spokane Valley, Washington
Conditions
PTSD, Depression, Opioid Use Disorder
Interventions
Modeling to Learn (MTL), Usual quality improvement (QI)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers

Food Choices in Healthy Weight Women

NCT02481362
Conditions
Addictive Behavior, Food Preferences, Food Habits, Healthy, Habituation
Interventions
CAKE, APRICOTS
Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Knoxville, Tennessee
Completed Phase 1 Interventional Results available

Boost Study 31380 (mHealth)

NCT05757453
Conditions
Addiction
Interventions
mHealth
Device
Lead sponsor
NXTech
Industry
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Astoria, New York
Completed Not applicable Interventional Results available

Clinical Trial of Smoking Cessation Mobile Phone Program

NCT02656745
Conditions
Nicotine Addiction, Drug Addiction, Drug Dependence, Substance Use Disorder, Tobacco Dependence
Interventions
Mobile Smoking Cessation Solution
Device
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Cocaine-Related Disorders, Heroin Dependence, Opioid-Related Disorders, Substance Abuse, Intravenous
Interventions
employment-based reinforcement
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland