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Showing 169–192 of 413 matching trials from the live ClinicalTrials.gov search.
Completed Early Phase 1 Interventional Results available

Behavioral Effects of Pregabalin and Cannabis

NCT01511640
Conditions
Cannabis-use Disorders
Interventions
Pregabalin, Placebo
Drug
Lead sponsor
Joshua A. Lile, Ph.D.
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

First Face Training Evaluation in Tribal Communities

NCT05998005
Conditions
Mental Health, Substance-Related Disorders
Interventions
First Face Training Program
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
14 Years and older
Enrollment
554 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
9
States / cities
Bonners Ferry, Idaho • Lapwai, Idaho • Plummer, Idaho + 6 more
Conditions
Smoking
Interventions
Mindfulness, Quit Line
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison, Wisconsin
Completed No phase listed Observational Accepts healthy volunteers

Translational Research Center in Lung Cancer Disparities (TRACER) Project 2

NCT05490251
Conditions
Smoking, Smoking Behaviors, Smoking Cessation, Stress Reaction
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Charleston, South Carolina
Conditions
Opioid-Dependence Among Adolescents
Interventions
buprenorphine, naltrexone, behavior therapy, voucher-based contingency management
Drug · Procedure
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
13 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
New York, New York
Recruiting Phase 4 Interventional Accepts healthy volunteers

Addiction Potential of Very Low Nicotine Filtered Little Cigars

NCT06630728
Conditions
Smoking (Tobacco) Addiction
Interventions
Reduced Nicotine Content Cigars, Normal nicotine content cigar, Usual brand cigar
Drug
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Stress Disorders, Post Traumatic, Substance-Related Disorders
Interventions
Cognitive Behavioral Therapy (CBT)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
3
States / cities
Concord, New Hampshire • Manchester, New Hampshire • Wilder, Vermont
Conditions
Nicotine Dependence
Interventions
Varenicline, Bupropion, Nicotine patches, Nicotine Inhaler
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
702 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Charlotte, North Carolina • Durham, North Carolina • Raleigh, North Carolina + 1 more
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Clinical Neurobiology of Serotonin and Addiction

NCT00732901
Conditions
Cocaine Dependence
Interventions
Escitalopram, Placebo
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 55 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Houston, Texas
Conditions
Smoking
Interventions
Quit smoking, Nicotine patch, Placebo Patch
Behavioral · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Depression, Marijuana Abuse
Interventions
Venlafaxine, Placebo
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New York, New York
Conditions
Stimulant Use (Diagnosis)
Interventions
Science to Service Laboratory
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
9
States / cities
Chicago, Illinois • Rockford, Illinois • Pawtucket, Rhode Island + 1 more
Conditions
HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions
Collaborative Care Model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Nicotine Addiction, Cigarette Smoking
Interventions
Nicotine, MR Compatible Nicotine Delivery Device
Drug · Device
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Stony Brook, New York
Completed Not applicable Interventional Results available

A Study to Help People Quit Smoking.

NCT01880099
Conditions
Nicotine Dependence
Interventions
placebo, Galantamine 8mg, Galantamine 16mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Drug Abuse
Interventions
Ramelteon, triazolam, and placebo (56 possible combinations total)
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Exercise on Chocolate Addiction

NCT03356509
Conditions
Acute Exercise and Addictive Behavior
Interventions
Exercise
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 45 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Coral Gables, Florida
Conditions
Nicotine Addiction
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Opioid Use Disorder, Chronic Pain
Interventions
Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT), Enhanced Treatment as Usual (ETAU)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
West Haven, Connecticut • Bedford, Massachusetts • Boston, Massachusetts + 1 more
Recruiting Phase 1 Interventional Accepts healthy volunteers

Open-Label Psilocybin Study in Transdiagnostic Population

NCT06442423
Conditions
Transdiagnostic, Depression - Major Depressive Disorder, Anxiety, PTSD Symptoms, PTSD, Substance Use, Substance Use Disorder (SUD), OCD
Interventions
Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Hepatitis C, Medication Adherence
Interventions
AiCure, AiCure with gamification
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Nicotine Addiction
Interventions
Scheduled Gradual Reduction + Varenicline, Scheduled Gradual Reduction + Placebo Drug, Basic Advice + Varenicline, Basic Advice + Placebo Drug
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Opioid-Related Disorders, Substance Withdrawal Syndrome
Interventions
Dynorphin 1 - 13
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1997
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Eating Disorders, Bulimia
Interventions
Guided self-help cognitive behavioral therapy (CBT), Usual clinical care
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 50 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
2
States / cities
Middletown, Connecticut • Portland, Oregon