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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:27 AM EST

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Benign Essential Blepharospasm Clear all

Conditions: Dystonia
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cervical Dystonia, Blepharospasm
Interventions: Xeomin®; Biological
Lead sponsor: Merz North America, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 688 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 70
States / cities: Cullman, Alabama • Scottsdale, Arizona • Tucson, Arizona + 60 more

Conditions: Focal Dystonia
Interventions: Topical acetyl hexapeptide-8, Placebo; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Blepharospasm
Interventions: No intervention- only one time survey; Other
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 81 Years
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 5
States / cities: Fountain Valley, California • Sarasota, Florida • Boston, Massachusetts + 2 more

Conditions: Blepharospasm, Dystonia, Other Eye and Face Disorders
Interventions: No intervention.; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 405 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 7
States / cities: Aurora, Colorado • Atlanta, Georgia • Chicago, Illinois + 4 more

Conditions: Blepharospasm
Interventions: incobotulinumtoxinA (Xeomin), Placebo; Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Blepharospasm
Interventions: Botulinum toxin type A; Biological
Lead sponsor: Ipsen; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 14
States / cities: Phoenix, Arizona • Fountain Valley, California • Los Angeles, California + 10 more

Conditions: Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp, Musician's Focal Hand Dystonia, Craniofacial Dystonia, Blepharospasm Oromandibular Dystonia
Interventions: MRI, Blood draw; Other · Procedure
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 21 Years to 80 Years
Enrollment: 141 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tears; Excess, Eyelid Spasm
Interventions: Botulinum toxin; Drug
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Benign Essential Blepharospasm, Hemifacial Spasm
Interventions: DaxibotulinumtoxinA; Drug
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Blepharospasm
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Blepharospasm, Dystonia, Spasm
Interventions: Mexiletine; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: Not listed
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2002
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cervical Dystonia, Blepharospasm, Limb Dystonia, Hemifacial Spasm, Spasticity, Muscle, Fragments of Torsion Dystonia
Interventions: Not listed
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: Not listed
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Focal Dystonia
Interventions: Acetyl-Hexapeptide Topical Treatment, placebo; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Blepharospasm, Blepharospasm, Benign Essential, CBD
Interventions: Cannabidiol Oral Solution [Epidiolex]; Drug
Lead sponsor: Silkiss Eye Surgery; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Oakland, California

Conditions: Dystonia, Focal Dystonia, Cerebellar Disease
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 47 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Dystonia
Interventions: Medtronic implantable deep brain stimulation (DBS) system; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 7 Years to 80 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 2
States / cities: San Francisco, California

Conditions: Blepharospasm, Dystonia
Interventions: Dipraglurant, Placebo; Drug
Lead sponsor: Addex Pharma S.A.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Benign Essential Blepharospasm
Interventions: Magstim RapidStim2, Sham Magstim RapidStim2; Device
Lead sponsor: University of Florida; Other
Eligibility: 30 Years to 75 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Blepharospasm
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Blepharospasm of Both Eyelids, Blepharospasm of Left Eyelid, Blepharospasm of Right Eyelid, Blepharospasm, Benign Essential, Blepharospasm
Interventions: Botulinum Neurotoxin Type A; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Blepharospasm, Focal Dystonia
Interventions: repetitive transcranial magnetic stimulation (rTMS); Procedure
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Search by objective public record fields.

Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives

Trial Evaluating Xeomin® (incobotulinumtoxinA) for Cervical Dystonia or Blepharospasm in the United States

Acetyl Hexapeptide-8 for Blepharospasm

Blepharospasm Patient Survey for Patients With Blepharospasm

Blepharospasm Tools

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Blepharospasm

Study of a Single Administration of 3 Doses of Dysport® for the Treatment of Benign Essential Blepharospasm

Brain Networks in Dystonia

Effect of Topical Botulinum Toxin Eyedrop on Palpebral Fissure

Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm

Brain Changes in Blepharospasm

Mexiletine for the Treatment of Focal Dystonia

Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin

A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm

Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm

Brain Changes in Blepharospasm

Deep Brain Stimulation in Patients With Dystonia

Exploratory Study of Dipraglurant (ADX48621) for the Treatment of Patients With Blepharospasm

rTMS and Botulinum Toxin in Benign Essential Blepharospasm

Photic Blink Reflex in People With Blepharospasm and Increased Blinking

DaxibotulinumtoxinA for Blepharospasm

Brain Stimulation to Treat Blepharospasm or Meige Syndrome