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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Bilateral Cataract Clear all
Completed Phase 4 Interventional

Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL

NCT01275118
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal IOL, crystalens Accommodating IOL
Device
Lead sponsor
Mark Packer, MD, FACS
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Jul 21, 2026, 7:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Visual Performance of Bilateral AcrySof ReSTOR Aspheric +4

NCT01215045
View directory record Official record
Conditions
Cataract
Interventions
AcrySof ReSTOR Aspheric +4
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2010 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

NCT06506669
View directory record Official record
Conditions
Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions
Oral sedation, Placebo
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Phase 4 Interventional

A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects

NCT07693205
View directory record Official record
Conditions
Cataract
Interventions
Clareon TruPlus, Clareon monofocal
Device
Lead sponsor
Berkeley Eye Center
Other
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Jul 21, 2026, 7:45 PM EDT
Enrolling by invitation No phase listed Observational

Binocular and Monocular Distance-Corrected Visual Performance and Defocus Characteristics of Clareon Truplus Intraocular Lens (IOL)

NCT07589894
View directory record Official record
Conditions
Cataract, Cataract Surgery, Cataract Bilateral, Cataract (Post-operative Cataract Surgery Follow-up)
Interventions
Clareon TruPlus IOL
Device
Lead sponsor
Colvard Kandavel Eye Center
Other
Eligibility
50 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jul 21, 2026, 7:45 PM EDT
Withdrawn Phase 1 Interventional

A Study of Levofloxacin Ocular Implant in Patients Undergoing Routine Bilateral Cataract Surgery

NCT05441930
View directory record Official record
Conditions
Cataract
Interventions
Levofloxacin Ocular Implant, Control
Drug
Lead sponsor
PolyActiva Pty Ltd
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
St Louis, Missouri • Ladson, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Symfony Toric Intraocular Lens Visual Outcomes

NCT03082599
View directory record Official record
Conditions
Cataract Bilateral, Astigmatism Bilateral
Interventions
Presbyopia and astigmatism correcting intraocular lens
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects

NCT06922084
View directory record Official record
Conditions
Cataract
Interventions
Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
Device · Drug
Lead sponsor
Berkeley Eye Center
Other
Eligibility
40 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Plymouth Meeting, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jul 21, 2026, 7:45 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Multifocals and Accommodating/Bilateral Implantation of Different Multifocal Intraocular Lens (IOLs)

NCT00934960
View directory record Official record
Conditions
Cataracts
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2009 · Synced Jul 21, 2026, 7:45 PM EDT
Not listed Not applicable Interventional

Prospective Evaluation and Comparison of Bilateral Synergy Implants and Bilateral PanOptix Implants

NCT05186298
View directory record Official record
Conditions
Cataract
Interventions
AcrySof® IQ PanOptix®, Synergy®, Cataract Surgery
Device · Procedure
Lead sponsor
Alterman, Modi, & Wolter Ophthalmic Physicians & Surgeons
Other
Eligibility
22 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Panama City, Florida • Poughkeepsie, New York • Kingston, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Jul 21, 2026, 7:45 PM EDT
Completed No phase listed Observational Results available

Symfony/Synergy IOL Combination Outcomes

NCT05604781
View directory record Official record
Conditions
Bilateral Cataract, Presbyopia
Interventions
Symfony & Synergy IOL combination
Device
Lead sponsor
Center For Sight
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Venice, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
View directory record Official record
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens

NCT00760487
View directory record Official record
Conditions
Cataract
Interventions
AcrySof Toric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2012 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3

NCT00719732
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2010 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)

NCT01166971
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR +3, Tecnis MF
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
3
States / cities
Panama City, Florida • Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 23, 2011 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

Visual Function Evaluation of Bilateral AcrySof ReSTOR Aspheric IOL

NCT00818116
View directory record Official record
Conditions
Cataracts
Interventions
AcrySof ReSTOR Aspheric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2010 · Synced Jul 21, 2026, 7:45 PM EDT
Completed No phase listed Observational Results available

AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study

NCT04126187
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
40 Years and older
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 21, 2026, 7:45 PM EDT
Not listed Phase 4 Interventional

Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.

NCT04592081
View directory record Official record
Conditions
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Interventions
Dextenza 0.4Mg Ophthalmic Insert
Drug
Lead sponsor
Kerry Assil, MD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Jul 21, 2026, 7:45 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL

NCT01278420
View directory record Official record
Conditions
Cataract
Interventions
Tecnis MF, ReSTOR
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
6
States / cities
Santa Barbara, California • Boynton Beach, Florida • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL

NCT00934622
View directory record Official record
Conditions
Cataract
Interventions
AcrySof® ReSTOR® Aspheric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2010 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Not applicable Interventional

This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to Study CDE and Ultrasound Time During Cataract Removal

NCT07468877
View directory record Official record
Conditions
Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery, Cataract Bilateral
Interventions
Cataract extraction with phacoemulsification comparing two systems
Device
Lead sponsor
Nicole Fram M.D.
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Phase 4 Interventional Results available

Visual Function With Bilateral AcrySof® ReSTOR® Aspheric SN6AD1

NCT00710931
View directory record Official record
Conditions
Cataract
Interventions
AcrySof ReSTOR Aspheric IOL model SN6AD1
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2011 · Synced Jul 21, 2026, 7:45 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery

NCT04205916
View directory record Official record
Conditions
Patient Preference
Interventions
Dexamethasone, Standard of care surgery
Drug · Other
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
22 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Garden City, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Jul 21, 2026, 7:45 PM EDT
Completed Not applicable Interventional Results available

Visual Function and Patient Satisfaction After Bilateral Implantation of AcrySof Natural ReSTOR (Model SN60D3) or AcrySof Natural Monofocal (Model SN60AT)

NCT00759668
View directory record Official record
Conditions
Cataract
Interventions
Acrysof Natural ReSTOR SN60D3, Acrysof Natural Monofocal SN60AT
Device
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2011 · Synced Jul 21, 2026, 7:45 PM EDT