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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Biomarkers of Aging Clear all
Completed No phase listed Observational

Biomarkers in Blood Samples From Older Breast Cancer Survivors

NCT01138345
View directory record Official record
Conditions
Breast Cancer
Interventions
gene expression analysis, reverse transcriptase-polymerase chain reaction, laboratory biomarker analysis, medical chart review, questionnaire administration
Genetic · Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
50 Years and older · Female only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Sep 7, 2026, 10:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atlas of Retinal Imaging in Alzheimer's Study

NCT03862222
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia, Aging, Cognitive Change
Interventions
Retinal Imaging, Pupillometry, Contrast Sensitivity, Neuropsychological Evaluation, APOE genotyping, blood draw, Gait Assessment, Actigraphy
Other · Diagnostic Test · Genetic
Lead sponsor
University of Rhode Island
Other
Eligibility
55 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
4
States / cities
Clearwater, Florida • St. Petersburg, Florida • Kingston, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy

NCT07675200
View directory record Official record
Conditions
Autophagy, Healthy Aging
Interventions
Spermidine, Placebo
Dietary Supplement
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Completed No phase listed Observational

The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery

NCT02496234
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Sapere Bio
Industry
Eligibility
50 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Emotional Well-being and Measures of Healthy Aging

NCT07334106
View directory record Official record
Conditions
Aging, Aging, Healthy, Aging Well, Aging, Biological
Interventions
Positive Emotion Skills Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Phase 4 Interventional Results available

Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults

NCT05786521
View directory record Official record
Conditions
Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
Interventions
Semaglutide Injectable Product, Lifestyle Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
65 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of NAD3 Supplementation on Biomarkers of Aging

NCT04276948
View directory record Official record
Conditions
Aging
Interventions
NAD3
Dietary Supplement
Lead sponsor
The Center for Applied Health Sciences, LLC
Industry
Eligibility
40 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sedentary Behavior Interrupted Randomized Controlled Trial (P2)

NCT03473145
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Health Coaching, activPAL inclinometer, Tools to Prompt Standing or Prompt Sit-to-Stand Transitions.
Behavioral · Device · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MS-ResearchBiomarkerS

NCT05204459
View directory record Official record
Conditions
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive, Clinically Isolated Syndrome, Radiologically Isolated Syndrome, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease, Neurologic Autoimmune Disease, Neurologic Disorder, Healthy Aging
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2041
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

ABSORB (Amount of Blueberries So Older Adults Reap Benefits)

NCT05937165
View directory record Official record
Conditions
Depressive Symptoms, Aging
Interventions
Freeze-dried Blueberry Powder
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Completed No phase listed Observational

Biomarkers of Aging as Predictors of Kidney Transplant Function

NCT02335333
View directory record Official record
Conditions
Delayed Graft Function, Other Complications of Kidney Transplant
Interventions
No treatment
Other
Lead sponsor
Sapere Bio
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mode of Exercise and Bone Biomarkers in Older Veterans

NCT05266976
View directory record Official record
Conditions
Aging, Musculoskeletal Diseases, Osteoporosis
Interventions
10 Weeks of Supervised Resistance Exercise Training, 10 Weeks of Supervised Endurance Exercise Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

NCT03954899
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
Interventions
melatonin, placebo
Dietary Supplement · Other
Lead sponsor
Natalie Denburg
Other
Eligibility
56 Years to 85 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Sedentary Behavior Interrupted: A Trial of Acute Effects on Biomarkers of Healthy Aging

NCT03511352
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Frequent sit-to-stands, Stand More
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
55 Years and older · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Sep 7, 2026, 10:26 PM EDT
Enrolling by invitation No phase listed Observational

Expanding Access to Cognitive Health Biomarker Testing at Home

NCT07594665
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Alzheimer's Dementia (AD), Subjective Cognitive Decline (SCD), Cognitive Aging
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults

NCT06942351
View directory record Official record
Conditions
Aging, Inflammation Biomarkers
Interventions
Walnuts, Crackers
Other
Lead sponsor
Oregon State University
Other
Eligibility
55 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Corvallis, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease

NCT03938870
View directory record Official record
Conditions
Alzheimer's Disease, Brain Diseases, Central Nervous System Diseases, Delirium, Dementia, Amnestic, Cognitive Disorders, Dementia, Mental Disorders, Nervous System Diseases, Neurodegenerative Diseases, Tauopathies
Interventions
L-Leucine 13C6
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Inovium Ovarian Rejuvenation Trials

NCT03178695
View directory record Official record
Conditions
Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions, Menopause Premature Symptomatic, Menopause Premature Asymptomatic, Premature Ovarian Failure, Premature Ovarian Failure, Familial, Premature Ovarian Failure 2A, Premature Ovarian Failure 3, Premature Ovarian Failure 4, Premature Ovarian Failure 1, Premature Ovarian Failure 5, Premature Ovarian Failure 6, Premature Ovarian Failure 7, Premature Ovarian Failure 9, Premature Ovarian Failure 8, Infertility, Infertility, Female, Infertility Unexplained
Interventions
Autologous PRP injection into human ovarian tissue
Other
Lead sponsor
Ascendance Biomedical
Industry
Eligibility
35 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2020 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Molecular Optimization Via Exercise (MOVE)

NCT06540287
View directory record Official record
Conditions
Aging
Interventions
Observational
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Novato, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 7, 2026, 10:26 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Aging and Disease Course: Contributions to Lifespan Neurobiology of Schizophrenia

NCT04951700
View directory record Official record
Conditions
Schizophrenia, Aging, Disease Course, Biomarker, Neuroimaging, Cognitive Dysfunction
Interventions
Other
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting No phase listed Observational

Parathyroidectomy and Mobility Study

NCT07103876
View directory record Official record
Conditions
Hyperparathyroidism, Parathyroid, Mobility
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

NCT02339012
View directory record Official record
Conditions
Healthy Volunteers, Non-Healthy/Non-Frail, Frail
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
20 Years to 120 Years
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2099
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 7, 2026, 10:26 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

SGLT2 Inhibition in Older Obese Adults With Pre-diabetes

NCT04401904
View directory record Official record
Conditions
Aging
Interventions
Dapagliflozin 10 mg, Nutritional counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 7, 2026, 10:26 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

100-Year Human Aging Study

NCT07563777
View directory record Official record
Conditions
Aging, Aging Well, All-Cause Mortality, Mortality, Metabolic Syndrome, Cardiovascular Diseases, Cognitive Dysfunction, Musculoskeletal Diseases, Neoplasms, Frailty, Activities of Daily Living, Health-Related Quality of Life, Disability Physical, Neuro-Degenerative Disease, Dementia
Interventions
Comprehensive Multi-System Clinical Screening
Diagnostic Test
Lead sponsor
Longevity Metrics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2099
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 7, 2026, 10:26 PM EDT