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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:29 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 128 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Biomechanics Clear all

Conditions: Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions: Carbon Fiber Custom Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Musculoskeletal Injuries
Interventions: PREPARE Initial Clinical Assessment - Pilot (two iterations), PREPARE Initial Clinical Assessment - Pre-Injury (one iteration), PREPARE Initial Clinical Assessment - Post-Injury (up to three iterations), PREPARE Optimized Clinical Assessment; Other
Lead sponsor: Womack Army Medical Center; Federal
Eligibility: 18 Years to 44 Years
Enrollment: 2,690 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 2
States / cities: Bethesda, Maryland • Fort Liberty, North Carolina

Conditions: Lower Limb Amputation Below Knee
Interventions: As-prescribed stiffness, Two categories stiffer than the as-prescribed stiffness, Two categories less stiff than the as-prescribed stiffness; Device
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 70 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Knee Injuries, Athletic Injuries
Interventions: Not listed
Lead sponsor: Steve Marshall; Other
Eligibility: 18 Years and older
Enrollment: 4,800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2011
U.S. locations: 3
States / cities: Colorado Springs, Colorado • Annapolis, Maryland • West Point, New York

Conditions: Kinematics
Interventions: Joint Motion Analysis; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 2 Years to 75 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2027
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Knee Osteoarthritis
Interventions: Whole Body Vibration; Other
Lead sponsor: California State University, Fullerton; Other
Eligibility: 18 Years to 35 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Fullerton, California

Conditions: Ambulation With the "Take Home" or Passive Prosthesis, Ambulation With the Motorized Prosthesis in the "Off" Configuration, Ambulation With the Motorized Prosthesis in the "Transparent" Condition, Ambulation With the Motorized Prosthesis in the "Powered" Condition
Interventions: Passive prosthesis, Motorized prosthesis; Device
Lead sponsor: Northern Arizona University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Flagstaff, Arizona

Conditions: Injury;Sports, Muscle Soreness
Interventions: Theragun Prime; Device
Lead sponsor: Point Loma Nazarene University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Cerebral Palsy (CP)
Interventions: Ankle Foot Orthoses-Footwear Combination, Traditional Solid Ankle AFO (TSAFO); Other
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 4 Years to 9 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Osteoarthritis, Knee
Interventions: Lidocaine Hydrochloride; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 45 Years and older
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Knee Osteoarthritis
Interventions: Foot Progression, Trunk Lean; Other
Lead sponsor: George Mason University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2026
U.S. locations: 1
States / cities: Manassas, Virginia

Conditions: Lower Limb Amputation Below Knee
Interventions: Fixed stiffness prosthesis, Automatic stiffness prosthesis; Device
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 79 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Osteoarthritis, Knee
Interventions: Triamcinolone Acetonide Extended-Release Injectable Suspension; Drug
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years to 75 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Cancer Bone, Bone Tumors
Interventions: Not listed
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 20 Years to 90 Years
Enrollment: 245 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2027
U.S. locations: 7
States / cities: Baltimore, Maryland • Boston, Massachusetts • Minneapolis, Minnesota + 4 more

Conditions: Amputation, Prosthesis User
Interventions: Standard-of-care prosthetic foot, Standard-of-care prosthetic foot with heel-stiffening wedge, Standard-of-care prosthetic foot of one category greater stiffness, Dual keel prosthetic foot, Powered ankle-foot; Device
Lead sponsor: VA Puget Sound Health Care System; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Adolescent Idiopathic Scoliosis
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 12 Years to 18 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Total Knee Arthroplasty (TKA)
Interventions: Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments; Behavioral · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 90 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 4
States / cities: Gainesville, Florida

Conditions: Osteoarthritis, Knee
Interventions: Shoe Insert; Device
Lead sponsor: Boston University; Other
Eligibility: 45 Years to 85 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ankle Inversion Sprain, Chronic Instability of Joint
Interventions: Joint Mobilization, Massage; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Biomechanics, Limb Length Discrepancy
Interventions: Controlled Ankle Movement Boot, EVENUp Lift; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 40 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Lower Extremity Problem
Interventions: Education Program on Injury Prevention, Individualized Feedback + Education Program on Injury Prevention; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Musculoskeletal Injury
Interventions: Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment; Other
Lead sponsor: Walter Reed National Military Medical Center; Federal
Eligibility: 18 Years to 40 Years
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 3
States / cities: Athens, Georgia • Bethesda, Maryland • Fort Bragg, North Carolina

Conditions: Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
Interventions: Carbon Fiber Custom Dynamic Orthosis (CDO); Device
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 65 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Hamstring Injury
Interventions: Patient Reported Outcomes Surveys, Clinical Assessments, Biomechanical and Neuromuscular Assessments, Conventional MRI; Other · Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 26 Years
Enrollment: 699 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 5
States / cities: Bloomington, Indiana • Notre Dame, Indiana • Chapel Hill, North Carolina + 2 more

Search by objective public record fields.

Custom Dynamic Orthoses to Reduce Articular Contact Stress

Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

Automatic Prosthetic Foot Stiffness Modulation to Improve Balance

Risk Factors for Anterior Cruciate Ligament (ACL) Injury

Biomechanics/Motion Analysis Laboratory Data Bank

Whole Body Vibration on Running Biomechanics

Investigation of Motorized Lower-limb Prostheses

Effects of Percussion Therapy on the Biomechanics of Pickleball Movement

Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations

Effect of Knee Pain on Walking Biomechanics

Effects of Gait Retraining on Lower Extremity Biomechanics

Automatic Prosthetic Foot Stiffness Modulation to Improve Balance in the Real World

Effect of Zilretta Injection

Biomechanics of Metastatic Defects in Bone

Lower Limb Prostheses for Individuals Who Carry Infants, Toddlers, and Other Loads

Function and Scoliosis Surgery

Total Knee Arthroplasty Biomechanics

Shoe Inserts for Treating Osteoarthritis of the Knee

Mechanisms of Manual Therapies in CAI Patients

Biomechanical Analysis of CAM Boot and EVENUp Lift

Injury Prevention for Female Lacrosse Athletes

Post-Concussion Musculoskeletal Injury Risks

Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics

Hamstring Injury (HAMIR) Index