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Showing 1–24 of 86 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Biopsy, Needle Clear all
Completed Not applicable Interventional Results available

Comparison of a Novel 22-gauge Core Biopsy Needle

NCT01598194
View directory record Official record
Conditions
Solid Pancreatic Mass Lesions, Malignant Neoplasm of Pancreas
Interventions
Novel 22-gauge Core Biopsy Needle + Standard Biopsy Needle
Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Jul 23, 2026, 12:04 PM EDT
Active, not recruiting Not applicable Interventional

Nature Sounds as a Pain and Anxiety Reducing Strategy in Patients Undergoing Breast Core Biopsy

NCT03238976
View directory record Official record
Conditions
Breast Cancer
Interventions
Nature sounds
Other
Lead sponsor
University of Chicago
Other
Eligibility
21 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS

NCT02167074
View directory record Official record
Conditions
Pancreatic Masses, Lymph Nodes
Interventions
25G FNA needle, 20G ProCore FNB needle
Device
Lead sponsor
Foundation for Liver Research
Other
Eligibility
18 Years to 100 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
3
States / cities
Irvine, California • New Haven, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2021 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy

NCT00734838
View directory record Official record
Conditions
Breast Cancer
Interventions
High Resolution Microendoscope
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Jul 23, 2026, 12:04 PM EDT
Not yet recruiting Not applicable Interventional

Comparison of FNB to EUS-CNB for Pancreatic Lesions

NCT07240818
View directory record Official record
Conditions
Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
Interventions
endoscopic ultrasound guided biopsy with core needle biopsy device, EUS-FNB
Device · Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 23, 2026, 12:04 PM EDT
Completed No phase listed Observational

DNA Microarray Study of Pancreas Cancer

NCT00680420
View directory record Official record
Conditions
Pancreas Cancer
Interventions
fine needle aspiration biopsy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional

19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB)

NCT04806607
View directory record Official record
Conditions
Chronic Liver Disease
Interventions
19G FNB, 22G FNB
Procedure
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Comparison of 19g FNA and 19g FNB Needles for EUS-LB

NCT03408171
View directory record Official record
Conditions
Abnormal Liver Function
Interventions
19-gauge FNA needle, 19-gauge FNB needle
Device
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Jul 23, 2026, 12:04 PM EDT
Completed No phase listed Observational

Molecular and Diagnostic Classification of Non-Small Cell Lung Cancer From Fine Needle Aspirates

NCT01630122
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Jul 23, 2026, 12:04 PM EDT
Completed No phase listed Observational

EchoTip AcuCore Post-Market Clinical Study

NCT06358001
View directory record Official record
Conditions
Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma, Malignant Lymphoma, Metastasis, Chronic Pancreatitis, Autoimmune Pancreatitis
Interventions
EchoTip AcuCore
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Orange, California • Denver, Colorado • Gainesville, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Early Phase 1 Interventional

Testing of Different Methods for Determining Whether Breast Cancer Has Spread to the Lymph Nodes

NCT00360152
View directory record Official record
Conditions
Breast Neoplasms
Interventions
Fine needle aspiration biopsy (FNAB), Sentinel Lymph Node Biopsy
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 3, 2013 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional

EUS-FNB With ROSE Vs. EUS-FNB Without ROSE

NCT03322592
View directory record Official record
Conditions
Biopsy, Fine-needle, Pancreatic Neoplasm
Interventions
Rapid on-site evaluation (ROSE), Histologic evaluation
Diagnostic Test
Lead sponsor
Azienda Ospedaliera Universitaria Integrata Verona
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Jul 23, 2026, 12:04 PM EDT
Not listed Phase 2 Interventional

PSMA PET Scan and mpMRI for Prostate Cancer Detection

NCT05820724
View directory record Official record
Conditions
Prostate Cancer Diagnosis
Interventions
PSMA PET scan, No PSMA PET, 18F- DCFPyl Injection
Diagnostic Test · Other · Drug
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
18 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2023 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional

The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma and/or DCIS in Patients Diagnosed With Intraductal Papilloma Without Atypia or Flat Epithelial Atypia by Core Needle Biopsy

NCT02489617
View directory record Official record
Conditions
Flat Epithelia Atypia, Intraductal Papilloma Without Atypia
Interventions
Pathologic evaluation of excised tissue
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
18
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Indianapolis, Indiana + 11 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jul 23, 2026, 12:04 PM EDT
Recruiting Not applicable Interventional

Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies

NCT06907446
View directory record Official record
Conditions
Prostate Cancer
Interventions
Comparison of Biopsy Needle Types for Prostate Biopsy
Diagnostic Test
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jul 23, 2026, 12:04 PM EDT
Not listed Not applicable Interventional

Randomized Trial for Optimal Number of Passes Required for Molecular Profiling During EUS-FNB of Pancreatic Cancer

NCT05043532
View directory record Official record
Conditions
Pancreatic Cancer, Pancreatic Neoplasms, Adenocarcinoma of the Pancreas
Interventions
2 passes during EUS-guided fine needle biopsy, 3 passes during EUS-guided fine needle biopsy
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Jul 23, 2026, 12:04 PM EDT
Withdrawn Phase 2 Interventional

Evaluation of a New EUS Guided Biopsy Needle (SharkCore) Comparing to Standard EUS Needle (ProCore)

NCT02766842
View directory record Official record
Conditions
Mesenchymal Tumor, Autoimmune Pancreatitis, Lymphoma, Solid Tumors
Interventions
EUS-FNB with ProCore needle, EUS-FNB with SharkCore needle, ProCore needle, SharkCore needle
Procedure · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Jul 23, 2026, 12:04 PM EDT
Withdrawn No phase listed Observational

Correlation of X-ray and Pathology With Needle Biopsy of Lung Tumors

NCT00638625
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

NCT01769248
View directory record Official record
Conditions
Pancreatic Cancer, Lymphadenopathy, Gastrointestinal Stromal Tumor
Interventions
Fine needle aspiration, Fine needle biopsy
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
3
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Jul 23, 2026, 12:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules

NCT01401855
View directory record Official record
Conditions
Cancer, Thyroid
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Jul 23, 2026, 12:04 PM EDT
Active, not recruiting Not applicable Interventional

Feasibility and Identification of Breast Cancer Patients for Potential Avoidance of Surgery

NCT02455791
View directory record Official record
Conditions
Breast Cancer
Interventions
Ultrasound-Guided Biopsy
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional

Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses

NCT02910960
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Acquire EUS Biopsy Device, SharkCore Biopsy System
Device
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

EUS GUIDED Transduodenal Biopsy Using the 19G Flex

NCT02307253
View directory record Official record
Conditions
Abdominal Neoplasms
Interventions
Expect™19Flex needle (Boston Scientific Corp.,Natick,MA,USA)
Device
Lead sponsor
Catholic University of the Sacred Heart
Other
Eligibility
18 Years to 90 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 23, 2026, 12:04 PM EDT
Completed Not applicable Interventional Results available

Pilot Study of Navigational Bronchoscopy and Transthoracic Needle Biopsy

NCT02109458
View directory record Official record
Conditions
Peripheral Pulmonary Nodules
Interventions
Navigation guided bronchoscopy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2017 · Synced Jul 23, 2026, 12:04 PM EDT