- Conditions
- Bipolar Disorder Type I With Mania
- Interventions
- KarXT, Lithium, Valproate, Lamotrigine
- Drug
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 52
- States / cities
- Glendale, Arizona • Bentonville, Arkansas • Little Rock, Arkansas + 41 more
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- Conditions
- Bipolar Disorder Type I With Mania or Mania With Mixed Features
- Interventions
- KarXT, Placebo
- Drug · Other
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 28
- States / cities
- Little Rock, Arkansas • Rogers, Arkansas • Culver City, California + 23 more
- Conditions
- Bipolar Disorder
- Interventions
- BHV-7000, Placebo
- Drug
- Lead sponsor
- Biohaven Therapeutics Ltd.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 32
- States / cities
- Bentonville, Arkansas • Little Rock, Arkansas • Rogers, Arkansas + 26 more