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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Blast Injury Clear all
Completed No phase listed Observational Accepts healthy volunteers

Early Digital, Analyte and Neurologic Biomarkers of Acute and Chronic Brain Injury and Recovery in CQT Instructors

NCT05917665
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Blast Overpressure Longitudinal Study

NCT07606651
View directory record Official record
Conditions
Low-level Blast Exposure
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 50 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
3
States / cities
Bethesda, Maryland • Fort Bragg, North Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional Results available

Brain Training to Enhance Frontal Lobe Reasoning

NCT01552473
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Brain Training Program 1, Brain Training Program 2
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
19 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Detection and Amelioration of Gamma Oscillation Abnormalities in Blast-Related Brain Injury

NCT03836976
View directory record Official record
Conditions
mTBI
Interventions
Auditory gamma sensory stimulation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Completed No phase listed Observational

Factors Affecting Return to Work Among OEF/OIF Veterans With Polytrauma

NCT00872690
View directory record Official record
Conditions
Multiple Trauma, Blast Injuries, Brain Injuries
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 6, 2026, 4:51 PM EDT
Completed No phase listed Observational

The Effects of Chronic Exposure to Low-Level Blasts

NCT01524822
View directory record Official record
Conditions
Tramatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 60 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 6, 2026, 4:51 PM EDT
Not listed No phase listed Observational

The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure

NCT00631436
View directory record Official record
Conditions
Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
Interventions
Not listed
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
20 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)

NCT01220713
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post-Concussive Syndrome
Interventions
Hyperbaric Oxygen Therapy
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
19 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Portsmouth, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2013 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blast Exposed Veterans With Auditory Complaints

NCT02122458
View directory record Official record
Conditions
Hearing Impairment, Hearing Aid Fitting
Interventions
mild-gain hearing aids with high-frequency emphasis over 6-months
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 50 Years
Enrollment
363 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
3
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania • Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 6, 2026, 4:51 PM EDT
Recruiting Phase 2 Interventional

Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure

NCT07131475
View directory record Official record
Conditions
Blast Injury
Interventions
PBR28 TSPO PET
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Symptom-Targeted Approach to Rehabilitation for Concussion

NCT05091970
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Manualized cognitive rehabilitation for mild traumatic brain injury (mTBI)
Procedure
Lead sponsor
South Texas Veterans Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 6, 2026, 4:51 PM EDT
Completed No phase listed Observational

Long-Term Effects of Repetitive, Low-Level Blast Exposure on Special Operations Forces Service Members

NCT05183087
View directory record Official record
Conditions
Traumatic Brain Injury, Blast Injuries
Interventions
3T Connectome MRI, 7 Tesla MRI, TSPO PET, Tau PET, Cognitive and Behavioral Assessments, Blood Biomarkers
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 45 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 6, 2026, 4:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Visual Prognosis in Non-Penetrating Corneal Blast Injuries

NCT00414219
View directory record Official record
Conditions
Corneal Foreign Body Following Blast Injury
Interventions
Visual quality of patients with corneal eye injuries
Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional Results available

Metacognitive Training to Enhance Strategy Use in Blast-Related TBI

NCT00857207
View directory record Official record
Conditions
Brain Concussion, Blast Injuries
Interventions
Goal Management Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional

LED Treatment to Improve Cognition and Promote Recovery in TBI

NCT02404402
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
LED, sham LED
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans

NCT06309264
View directory record Official record
Conditions
Auditory Diseases, Central
Interventions
Phonak Lumina P90
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
3
States / cities
Loma Linda, California • Sepulveda, California • West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)

NCT01138020
View directory record Official record
Conditions
Traumatic Brain Injury, Cognitive Symptoms
Interventions
Cognitive Intervention, Educational intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 6, 2026, 4:51 PM EDT
Not listed No phase listed Observational

Advanced MRI in Blast-related TBI

NCT00785304
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Protection Against Potential Brain, Hearing and Vision Injury During Blast Wave Exposure

NCT03017924
View directory record Official record
Conditions
Concussion, Mild
Interventions
Q collar
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 6, 2026, 4:51 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

NCT04026568
View directory record Official record
Conditions
Nerve Injury
Interventions
4-Aminopyridine, Placebo oral tablet
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 6, 2026, 4:51 PM EDT
Active, not recruiting No phase listed Observational

Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure

NCT04313712
View directory record Official record
Conditions
Blast or Combat Exposure, Head Injury Trauma
Interventions
ibogaine with magnesium treatment
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 6, 2026, 4:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Central Auditory Processing Deficits Associated With Blast Exposure

NCT01567020
View directory record Official record
Conditions
Blast Injuries, Brain Injuries, Age Factors
Interventions
Diagnostic
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional Results available

Peer Visitation for OEF/OIF Veterans

NCT01193686
View directory record Official record
Conditions
Polytrauma, Blast Injuries
Interventions
Peer Visitation
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 6, 2026, 4:51 PM EDT
Completed Not applicable Interventional

Evaluating Blast-X® in Combination With Negative Pressure Wound Therapy

NCT04265170
View directory record Official record
Conditions
Pressure Ulcer
Interventions
BlastX with negative pressure therapy
Device
Lead sponsor
SerenaGroup, Inc.
Network
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kittanning, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 6, 2026, 4:51 PM EDT