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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:24 PM EDT

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Showing 1–24 of 115 matching trials from the live ClinicalTrials.gov search.
Conditions
Closed Femur Fracture
Interventions
Blood Flow Restriction, Delfi PTSII Tourniquet System
Other · Device
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
8
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Bethesda, Maryland + 5 more
Terminated Not applicable Interventional Results available

Blood Flow Restriction After Meniscus Repair

NCT04436523
Conditions
Meniscus Disorder, Meniscus, Torn Tibial, Meniscus Lesion, Meniscus Tear, Tibial, Atrophy, Muscular
Interventions
Blood flow restriction (Delfi Personalized Tourniquet System), Standard rehabilitation
Device · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Francisco, California
Conditions
Anterior Cruciate Ligament Tear
Interventions
Delfi, Standard rehabilitation
Device · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 30 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Withdrawn Not applicable Interventional Accepts healthy volunteers

Eccentric Resistance Training With Blood Flow Restriction on Muscle Function

NCT04977804
Conditions
Blood Flow Restriction
Interventions
Exercise, Eccentric plus blood-flow restriction
Other
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Logan, Utah
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BFR Therapy in Patients With Rotator Cuff Tears

NCT04384120
Conditions
Blood Flow Restriction
Interventions
Blood Flow Restriction Therapy, Traditional Therapy
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training for People With Disabilities

NCT06441422
Conditions
Weakness, Muscle
Interventions
Blood flow restriction training, No blood flow restriction training
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Terminated Not applicable Interventional

Blood Flow Restriction Concussion

NCT03695042
Conditions
Concussion Post Syndrome
Interventions
Blood Flow Restriction Training with Exercise
Other
Lead sponsor
Duke University
Other
Eligibility
14 Years to 30 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Impact of Blood Flow Restriction (BFR) on Exercise and Hemodynamic Responses

NCT03540147
Conditions
Exercise Training, Hemodynamic Response
Interventions
Hokanson Cuffs, BStrong Bands
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Austin, Texas
Conditions
Prehabilitation
Interventions
Prehabilitation Program
Combination Product
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Conditions
Tibial Plateau Fractures
Interventions
Blood Flow Restriction Cuff, Physical Therapy
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Achilles Tendon Rupture, Achilles Tendon Surgery
Interventions
Blood flow restriction augmented physical therapy, Physical therapy
Device · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Sex-specific Effect of Restricted Sleep on Brain Health

NCT05920759
Conditions
Cerebrovascular Circulation
Interventions
Cerebral blood flow
Diagnostic Test
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training in Patients With Lower Extremity Fractures

NCT06496035
Conditions
Tibial Fractures, Lower Extremity Fracture
Interventions
Blood Flow Restriction with low load exercise, Therapeutic Exercise
Device · Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Denver, Colorado
Conditions
Lateral Epicondylitis
Interventions
Blood Flow Restriction Device, Standard Physical Therapy
Device · Other
Lead sponsor
Julie Nuelle
Other
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions
Blood Flow Restriction (BFR) Therapy, Physical Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Anterior Cruciate Ligament Injury
Interventions
DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
Interventions
Blood Flow Restriction Therapy, Standard Physical Therapy
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
Interventions
Delfi Training Device
Device
Lead sponsor
Teri Herberger
Other
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Salisbury, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Flow Restriction Training for The Shoulder

NCT04540367
Conditions
Healthy
Interventions
Blood flow restriction therapy
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Completed No phase listed Observational Accepts healthy volunteers

Blood Flow Restriction on EMG During UQYBT

NCT07707960
Conditions
Shoulder and Upper Arm Injury
Interventions
Blood flow restriction unit
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training on Upper Extremity Grip Strength

NCT06535373
Conditions
Healthy Volunteers
Interventions
Blood flow restriction
Other
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Repair
Interventions
Cross-Education, Blood-Flow Restriction Training
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Knee Injuries, Anterior Cruciate Ligament Injuries
Interventions
Blood Flow Restriction Therapy, Standard Postoperative Physical Therapy
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Redwood City, California
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training With Blood Flow Restriction

NCT05863039
Conditions
Healthy
Interventions
Blood flow restriction, Regular training type 1, Regular training type 2
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Norman, Oklahoma