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Showing 1–24 of 88 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Blood Flow Restriction Training Clear all
Completed Not applicable Interventional Accepts healthy volunteers

BFR Therapy Following DRF

NCT05396521
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Blood Flow Restriction, Standard of Care Physical Therapy
Other
Lead sponsor
Carilion Clinic
Other
Eligibility
50 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Terminated Not applicable Interventional Results available

Blood Flow Restriction Training in ACL Surgery

NCT05245864
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
blood flow restriction, physical therapy standard of care
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 34 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Therapy in Lower Limb Extensor Injuries

NCT04149977
View directory record Official record
Conditions
Lower Limb Injury
Interventions
Physical Therapy with pressure cuff, Physical Therapy with placebo pressure cuff
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Not listed Not applicable Interventional

Blood Flow Restriction Exercise in the Treatment of Lateral Epicondylalgia Traditional Treatment

NCT04607356
View directory record Official record
Conditions
Tennis Elbow, Lateral Epicondylitis
Interventions
Blood Flow Restriction (BFR), Evidence-informed care
Device · Other
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction Training After Patellar INStability

NCT04554212
View directory record Official record
Conditions
Patellar Dislocation, Knee Injuries, Leg Injury, Wounds and Injuries
Interventions
Blood Flow Restriction Training, Sham Blood Flow Restriction Training
Device
Lead sponsor
Caitlin Conley
Other
Eligibility
14 Years to 40 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
4
States / cities
Lexington, Kentucky • Foxborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training for People With Disabilities

NCT06441422
View directory record Official record
Conditions
Weakness, Muscle
Interventions
Blood flow restriction training, No blood flow restriction training
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

BFRT for Severe Lower Extremity Muscle Atrophy

NCT04357184
View directory record Official record
Conditions
Severe Muscle Atrophy, Muscle Weakness
Interventions
Blood flow restriction training
Other
Lead sponsor
Cincinnati Sportsmedicine Research and Education Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size.

NCT03983070
View directory record Official record
Conditions
Healthy
Interventions
Seated Rowing Ergometer, Deadlift, Blood flow restriction
Other
Lead sponsor
Campbell University, Incorporated
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Buies Creek, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional

Does Blood Flow Restriction Training Improve Quadriceps Function After Arthroscopic Knee Surgery?

NCT03096366
View directory record Official record
Conditions
Quadriceps Atrophy, ACL Reconstruction
Interventions
Blood flow restriction, Physical therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional

BFR After Biceps Tendon Repair and MPFLR

NCT05375071
View directory record Official record
Conditions
Patellofemoral Joint Dislocation, Bicep Tendon Rupture
Interventions
Blood Flow Restriction (BFR) Therapy, Physical Therapy
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Early Phase 1 Interventional

Application of Ergogenic Aids to the Prehabilitation of Abdominal Cancer Patients Undergoing Cancer Surgery

NCT04073381
View directory record Official record
Conditions
Prehabilitation
Interventions
Prehabilitation Program
Combination Product
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cardiovascular Response to Isometric BFR Exercise

NCT06529068
View directory record Official record
Conditions
Blood Pressure
Interventions
Isometric handgrip exercise, Isometric handgrip exercise with a narrow-elastic band, Isometric handgrip exercise with a wide-rigid cuff
Behavioral
Lead sponsor
Hirofumi Tanaka
Other
Eligibility
18 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BFR Therapy in Patients With Rotator Cuff Tears

NCT04384120
View directory record Official record
Conditions
Blood Flow Restriction
Interventions
Blood Flow Restriction Therapy, Traditional Therapy
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Results available

Blood Flow Restriction Training (BFR) in an Adolescent Population

NCT04285879
View directory record Official record
Conditions
Blood Flow Restriction, ACL Tear, ACL Injury
Interventions
Blood Flow Restriction using Delfi Personalized Tourniquet System
Device
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Results available

Blood Flow Restriction Training in Individuals Awaiting Total Knee Replacement

NCT06111690
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Blood Flow Restriction Training (BFRT)
Procedure
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Blood Flow Restriction Training for The Shoulder

NCT04540367
View directory record Official record
Conditions
Healthy
Interventions
Blood flow restriction therapy
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional

Combined NMES and BFR Training After TKA

NCT04347343
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Standard Rehabilitation + Neuromuscular Electrical Stimulation and Blood Flow Restriction
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Withdrawn Not applicable Interventional

Blood Flow Restriction Therapy Improves Tibial Plateau Fracture Recovery

NCT06589115
View directory record Official record
Conditions
Tibial Plateau Fractures
Interventions
Blood Flow Restriction Cuff, Physical Therapy
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training and Blood Flow Restriction

NCT04938947
View directory record Official record
Conditions
Blood Flow Restriction and Low-Intensity Resistance Training
Interventions
Blood Flow Restriction Cuffs, Low-Intensity Resistance Training, High-Intensity Resistance Training
Device · Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 30 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 31, 2022 · Synced Sep 2, 2026, 9:14 PM EDT
Enrolling by invitation Not applicable Interventional

Blood Flow Restriction for Ulnar Sided Wrist Pain

NCT06963671
View directory record Official record
Conditions
Ulnar Wrist Pain
Interventions
Blood Flow Restriction
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Blood Flow Restriction Therapy Following ACL Tear

NCT04374968
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear, Knee Injuries, Sport Injury
Interventions
Blood flood restriction cuff
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Sep 2, 2026, 9:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)

NCT06664827
View directory record Official record
Conditions
Healthy, Healthy Male and Female Subjects, Healthy Volunteers
Interventions
Delfi PTS Blood Flow Restriction Tourniquet System
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 2, 2026, 9:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction

NCT05012982
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
AirBand, uninflated AirBand
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Milford, Connecticut • North Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 2, 2026, 9:14 PM EDT