- Conditions
- Excessive Bleeding During Surgery
- Interventions
- Hemoblast Bellows application
- Drug
- Lead sponsor
- WakeMed Health and Hospitals
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Raleigh, North Carolina
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Showing 1–24
of 57
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Surgical Hemostasis
- Interventions
- rThrombin
- Biological
- Lead sponsor
- ZymoGenetics
- Industry
- Eligibility
- 2 Years to 75 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Spinal Injuries, Spinal Deformity
- Interventions
- Tranexamic Acid, Placebo
- Drug
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 252 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 4
- States / cities
- San Francisco, California • Louisville, Kentucky • New York, New York + 1 more
- Conditions
- Vascular Surgical Bleeding
- Interventions
- Fibrin Sealant Grifols, Manual Compression
- Biological · Procedure
- Lead sponsor
- Instituto Grifols, S.A.
- Industry
- Eligibility
- Not listed
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 27
- States / cities
- Florence, Alabama • Palo Alto, California • San Diego, California + 23 more
- Conditions
- Hemorrhage
- Interventions
- TachoSil, Surgicel Original
- Biological
- Lead sponsor
- Corza Medical GmbH
- Industry
- Eligibility
- 1 Month and older
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 9
- States / cities
- Torrance, California • Lakewood, Colorado • Washington D.C., District of Columbia + 6 more
- Conditions
- Intraoperative Bleeding, Liver Diseases, Gallbladder Diseases, Hemorrhage, Surgical
- Interventions
- GATT-Patch, SURGICEL® Original
- Device
- Lead sponsor
- GATT Technologies BV
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 6
- States / cities
- Los Angeles, California • St Louis, Missouri • Pennington, New Jersey + 3 more
- Conditions
- Congenital Bleeding Disorder, Haemophilia A
- Interventions
- turoctocog alfa pegol
- Drug
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Eligibility
- 12 Years and older · Male only
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 19
- States / cities
- Phoenix, Arizona • Long Beach, California • Sacramento, California + 16 more
- Conditions
- Hemostasis, General Surgery
- Interventions
- sFilm-FS, TACHOSIL®
- Combination Product
- Lead sponsor
- Sealantium Medical Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Blood Loss
- Interventions
- Hemostatic Matrix
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- Not listed
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Surgical Hemostasis
- Interventions
- rThrombin, bovine thrombin
- Biological · Drug
- Lead sponsor
- ZymoGenetics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 401 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 29
- States / cities
- Birmingham, Alabama • Arcadia, California • Glendale, California + 21 more
- Conditions
- Coronary Artery Disease
- Interventions
- Not listed
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Blood Loss, Surgical
- Interventions
- Volta tAN System, SHAM Volta tAN System
- Device
- Lead sponsor
- University Surgical Vascular
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Watkinsville, Georgia
- Conditions
- Hemorrhage
- Interventions
- EVARREST® Fibrin Sealant Patch, Standard of Care (SoC)
- Biological · Other
- Lead sponsor
- Ethicon, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • Augusta, Georgia • Chicago, Illinois + 5 more
- Conditions
- Curvature of Spine
- Interventions
- Tranexamic Acid
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Soft Tissue Surgical Bleeding
- Interventions
- Fibrin Sealant (FS) Grifols, Surgicel®
- Biological · Device
- Lead sponsor
- Grifols Biologicals, LLC
- Industry
- Eligibility
- Not listed
- Enrollment
- 327 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 17
- States / cities
- Florence, Alabama • Pasadena, California • Bridgeport, Connecticut + 13 more
- Conditions
- Acquired Bleeding Disorder, Bleeding During/Following Surgery
- Interventions
- standard therapy, placebo, activated recombinant human factor VII
- Drug
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2003
- U.S. locations
- 7
- States / cities
- Little Rock, Arkansas • Duarte, California • Baltimore, Maryland + 4 more
- Conditions
- Scoliosis, Kyphosis, Lordosis, Spondylitis, Spinal Stenosis
- Interventions
- Epsilon-Aminocaproic Acid (EACA), Placebo
- Drug
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 182 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2006
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Congenital Bleeding Disorder, Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
- Interventions
- activated recombinant human factor VII, factor IX, factor VIII
- Drug · Other
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Eligibility
- 5 Years and older
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2004
- U.S. locations
- 14
- States / cities
- Los Angeles, California • Chicago, Illinois • New Orleans, Louisiana + 9 more
- Conditions
- Hemorrhage, Soft Tissue Bleeding
- Interventions
- EVARREST™ Fibrin Sealant Patch, Standard of Care
- Biological · Other
- Lead sponsor
- Ethicon, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Blood Loss, Surgical
- Interventions
- Vasopressin
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 60 Years · Female only
- Enrollment
- 152 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Blood Loss, Surgical
- Interventions
- Fibrin Sealant 2 (FS2), Oxidized Regenerated Cellulose (Surgicel)
- Drug · Device
- Lead sponsor
- Ethicon, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 135 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 16
- States / cities
- Los Angeles, California • Jacksonville, Florida • Miami, Florida + 12 more
- Conditions
- Congenital Bleeding Disorder, Haemophilia A
- Interventions
- turoctocog alfa
- Drug
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Eligibility
- 12 Years to 65 Years · Male only
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 18
- States / cities
- Little Rock, Arkansas • Long Beach, California • Tampa, Florida + 15 more
- Conditions
- Bleeding Reduction
- Interventions
- Acute Normovolemic Hemodilution
- Procedure
- Lead sponsor
- Inova Health Care Services
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Falls Church, Virginia
- Conditions
- Blood Loss, Surgical
- Interventions
- Ecallantide, Placebo
- Drug
- Lead sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 15
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Aurora, Colorado + 8 more