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ClinicalTrials.gov public records Last synced Oct 16, 2026, 2:06 AM EDT

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Showing 721–744 of 3,928 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Blood Pressure, High Clear all
Withdrawn Phase 1Phase 2 Interventional

A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia

NCT06327373
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Oxygen, Room air
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
11
States / cities
Durham, North Carolina • Henderson, North Carolina • Roxboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 16, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension

NCT07563322
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Nicotinamide Riboside (NR), Placebo
Dietary Supplement · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional

MI-BP: mHealth to Improve Blood Pressure Control

NCT02955537
View directory record Official record
Conditions
Hypertension
Interventions
MI-BP
Other
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 70 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 16, 2026, 2:06 AM EDT
Not listed Not applicable Interventional

Evaluation of a Decision Support Tool

NCT02060981
View directory record Official record
Conditions
Medication Adherence, Hypertension, Decision Making, Shared, Patient-Centered Outcomes Research
Interventions
Control, Interview Only, Interview plus decision support tool
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Phase 3 Interventional Results available

Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER

NCT03068130
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Bardoxolone methyl
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 85 Years
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
46
States / cities
Phoenix, Arizona • Beverly Hills, California • La Jolla, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons

NCT00194428
View directory record Official record
Conditions
Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
Interventions
Almond enriched diet, Low fat caloric diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Phase 2 Interventional Results available

Study of Cardiovascular Disease and Obstructive Sleep Apnea

NCT01637623
View directory record Official record
Conditions
Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour), Hypertension
Interventions
Losartan, Allopurinol, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
4
States / cities
Green Bay, Wisconsin • La Crosse, Wisconsin • Madison, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Phase 4 Interventional Results available

Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAH

NCT00439946
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
treprostinil, Crono Five ambulatory pump
Drug · Device
Lead sponsor
United Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
San Francisco, California • New York, New York • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 3, 2024 · Synced Oct 16, 2026, 2:06 AM EDT
Completed No phase listed Observational Results available

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus Hydrochlorothiazide

NCT05125224
View directory record Official record
Conditions
Hypertension
Interventions
Dihydropyridine calcium channel blocker, Hydrochlorothiazide
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
163,720 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Phase 3 Interventional Results available

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

NCT03037580
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Preserved Ejection Fraction
Interventions
Oral treprostinil, Placebo
Drug
Lead sponsor
United Therapeutics
Industry
Eligibility
18 Years to 85 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
82
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 66 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 16, 2026, 2:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Topcon 3D OCT-1000 Optical Coherence Tomography System

NCT00792259
View directory record Official record
Conditions
Retinal Disease, Glaucoma
Interventions
Not listed
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
4
States / cities
Bronxville, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Feasibility of HIIT in Older Adults with HIV and Hypertension

NCT06888596
View directory record Official record
Conditions
HIV, Hypertension, Exercise
Interventions
Exercise
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Phase 4 Interventional

A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Patients With Primary Open Angle Glaucoma

NCT06407973
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
OMNI Surgical System, Latanoprost plus adjunctive glaucoma medication
Device · Drug
Lead sponsor
Sight Sciences, Inc.
Industry
Eligibility
45 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Petaluma, California • Maryville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Phase 4 Interventional

Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%

NCT00440141
View directory record Official record
Conditions
Glaucoma, Ocular Hypertension
Interventions
latanoprost 0.005% eye drops and brimonidine 0.1% eye drops, latanoprost 0.005% eye drops and brinzolamide 1.0% eye drops
Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 2, 2008 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vouchers to Increase Uptake of Already Free Eye Care

NCT04426331
View directory record Official record
Conditions
Glaucoma, Eye Diseases
Interventions
Voucher Without Value Information, Voucher With Value Information
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
739 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Not applicable Interventional Results available

Eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES):

NCT02027272
View directory record Official record
Conditions
Eclampsia
Interventions
Dexamethasone
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional Results available

Reducing Adverse Self-Medication Behaviors in Older Adults With Hypertension

NCT00201201
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Hypertension
Interventions
Education Intervention, Control
Other
Lead sponsor
University of Connecticut
Other
Eligibility
60 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 3, 2014 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional

Guidelines for Drug Therapy of Hypertension: Closing the Loop

NCT00012636
View directory record Official record
Conditions
Hypertension
Interventions
Computer generated statements about guideline concordance of drug therapy deliver to clinicians
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
36 participants
Timeline
Ends 2000
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID)

NCT02167035
View directory record Official record
Conditions
Glaucoma, Ocular Hypertension
Interventions
Combigan Two Times Daily (BID), Simbrinza Three Times Daily (TID)
Drug
Lead sponsor
Cornerstone Health Care, PA
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Oct 16, 2026, 2:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Vinyasa Yoga on Vascular Function

NCT04226235
View directory record Official record
Conditions
Hypertension
Interventions
Yoga session
Behavioral
Lead sponsor
Texas State University
Other
Eligibility
20 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 16, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional

Addressing Hypertension Care in Africa Program

NCT06986590
View directory record Official record
Conditions
Hypertension, High Blood Pressure
Interventions
ADHINCRA Program
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 16, 2026, 2:06 AM EDT
Recruiting Phase 2 Interventional

Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension

NCT07090161
View directory record Official record
Conditions
Hypertension, Uncontrolled Hypertension
Interventions
iloperidone, Placebo
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
28
States / cities
Phoenix, Arizona • Tempe, Arizona • Tucson, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 16, 2026, 2:06 AM EDT
Terminated Phase 2 Interventional Results available

A Study Of Different Doses Of TBC3711 In Patients With Uncontrolled High Blood Pressure Already Taking Medications For High Blood Pressure.

NCT00272961
View directory record Official record
Conditions
Resistant Hypertension
Interventions
Placebo, TBC3711
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Birmingham, Alabama • Mobile, Alabama • Atlanta, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 16, 2026, 2:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Ester and Salt (KEAS) in Young Adults

NCT05545501
View directory record Official record
Conditions
Salt; Excess, Hypertension
Interventions
No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
19 Years to 39 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 16, 2026, 2:06 AM EDT