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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:26 AM EDT

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Showing 1–24 of 81 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Blood Pressure Reduction Clear all
Completed Not applicable Interventional Results available

Reducing Disparities in the Treatment of Hypertension Using the OWL mHealth Tool

NCT03974334
View directory record Official record
Conditions
Hypertension
Interventions
OWL-Hypertension 8 Wk Trial
Behavioral
Lead sponsor
Paula Gardiner
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Traffic Pollution Exposure Improves Blood Pressure

NCT04029129
View directory record Official record
Conditions
Air Pollution
Interventions
Air filtration and building envelop modifications
Other
Lead sponsor
UConn Health
Other
Eligibility
40 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 19, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Preventing Cognitive Decline by Reducing BP Target Trial

NCT05106036
View directory record Official record
Conditions
Cognitive Decline, Blood Pressure, Hypertension
Interventions
Clinical Support Decision Tool
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
70 Years and older
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 19, 2026, 2:26 AM EDT
Terminated Not applicable Interventional

Blood Pressure, Heart Rate Variability & Sleep in Veterans With PTSD

NCT01920451
View directory record Official record
Conditions
Insomnia, Posttraumatic Stress Disorder, Hypertension, Cardiovascular Disease
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTI)
Behavioral
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 6, 2014 · Synced Oct 19, 2026, 2:26 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reduced Volume of Inspiratory Resistance Training

NCT05744817
View directory record Official record
Conditions
Hypertension
Interventions
Inspiratory muscle strength training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 19, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

NCT04502225
View directory record Official record
Conditions
Supine Hypertension, Autonomic Failure
Interventions
Tilt, Elevated trunk, Tilt - In home, Elevated Trunk - In home
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindfulness Based Stress Reduction for High Blood Pressure

NCT00440596
View directory record Official record
Conditions
Hypertension
Interventions
Mindfulness based stress reduction, Progressive Muscle Relaxation
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
30 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 19, 2026, 2:26 AM EDT
Terminated Phase 2 Interventional Results available

Application of Impedance Threshold Device Technologies to Treat and Prevent Hypotension During Dialysis

NCT00576524
View directory record Official record
Conditions
Intradialytic Hypotension, End Stage Renal Disease, Low Blood Pressure
Interventions
ITD, Sham
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 26, 2013 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Phase 4 Interventional Results available

Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes

NCT02796170
View directory record Official record
Conditions
Type 2 Diabetes, Hypertension
Interventions
Dapagliflozin, Placebo
Drug
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults

NCT04074941
View directory record Official record
Conditions
Hypertension, Physical Disability, Aging
Interventions
Dietary intervention
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Revere, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Phase 4 Interventional Results available

Effect of High and Low Sodium Diets on Blood Pressure in Hypertensive Patients Treated With Aliskiren

NCT00441064
View directory record Official record
Conditions
Hypertension
Interventions
Aliskiren
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 60 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
19
States / cities
Orangevale, California • Brooklyn Center, Minnesota • Butte, Montana + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2011 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Mindfulness-Based Blood Pressure Reduction (MB-BP) Intervention Development - Stage 1 Single Arm Trial

NCT02702258
View directory record Official record
Conditions
Prehypertension, Hypertension
Interventions
MB-BP
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Phase 2 Interventional

Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

NCT00621816
View directory record Official record
Conditions
Hypertension
Interventions
nitroprusside, placebo infusion
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
1 Day to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Little Rock, Arkansas • Stanford, California • Louisville, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2011 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Grapefruit Feeding Trial in Healthy, Overweight Adults

NCT01452841
View directory record Official record
Conditions
Weight Loss, Obesity, Cardiovascular Risk Factors
Interventions
Grapefruit, Control
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 17, 2011 · Synced Oct 19, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement

NCT07091851
View directory record Official record
Conditions
Stroke, Hypertension, Home Blood Pressure Monitoring, Implementation Research
Interventions
Group medical visits and home blood pressure monitoring
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
35 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 19, 2026, 2:26 AM EDT
Not yet recruiting Not applicable Interventional

Navigating Hypertension and Food Insecurity

NCT07544836
View directory record Official record
Conditions
Hypertension (HTN), Food Insecurity
Interventions
Produce Prescription Only, Community Health Worker navigated Produce Prescription
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
20 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Honokaa, Hawaii • Waianae, Hawaii • Waimanalo, Hawaii
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 19, 2026, 2:26 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effectiveness of Vitamin D Supplementation

NCT02513823
View directory record Official record
Conditions
Elevated Blood Pressure, Endothelial Dysfunction
Interventions
2,000 International Units (IU)of vitamin D3
Dietary Supplement
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older · Female only
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 19, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

NCT06055036
View directory record Official record
Conditions
Cardiometabolic Syndrome, Physical Inactivity, Hypertension, Type 2 Diabetes, PreDiabetes, Obesity, Cardiovascular Diseases, Smoking, Sleep, Hyperlipidemias, Diet, Healthy, Blood Pressure
Interventions
Black Impact Intervention
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Male only
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 19, 2026, 2:26 AM EDT
Active, not recruiting Not applicable Interventional

Cancer and Blood Pressure Management, CARISMA Study

NCT04467021
View directory record Official record
Conditions
Cardiovascular Disorder, Chronic Kidney Disease, Metastatic Renal Cell Carcinoma, Metastatic Thyroid Gland Medullary Carcinoma, Stage IV Renal Cell Cancer AJCC v8, Stage IV Thyroid Gland Medullary Carcinoma AJCC v8, Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8, Stage IVB Thyroid Gland Medullary Carcinoma AJCC v8, Stage IVC Thyroid Gland Medullary Carcinoma AJCC v8
Interventions
Best Practice, Blood Pressure Measurement, Clinical Management, Quality-of-Life Assessment, Questionnaire Administration
Other
Lead sponsor
ECOG-ACRIN Cancer Research Group
Network
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
25
States / cities
Creve Coeur, Missouri • St Louis, Missouri • The Bronx, New York + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Reducing Sedentary Behavior to Improve Sleep: an Ancillary Study to the RESET BP Clinical Trial

NCT03946228
View directory record Official record
Conditions
Sleep, Obstructive Sleep Apnea, Insomnia
Interventions
Behavioral Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Inorganic Nitrate Supplement on Blood Pressure

NCT03909789
View directory record Official record
Conditions
Blood Pressure, Endothelial Dysfunction
Interventions
Plant based bioequivalent Nitrate supplementation, Placebo
Dietary Supplement
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 19, 2026, 2:26 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure

NCT05690464
View directory record Official record
Conditions
Blood Pressure
Interventions
magnesium glycinate supplement, placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
30 Years to 74 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients

NCT01261884
View directory record Official record
Conditions
Hypertension, Pregnancy, Preeclampsia, Exercise
Interventions
Exercise support, Exercise intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2015 · Synced Oct 19, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Take a STAND 4 Health: A Sedentary Behavior Reduction Intervention

NCT03698903
View directory record Official record
Conditions
Blood Pressure
Interventions
Take a STAND 4 Health
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 19, 2026, 2:26 AM EDT