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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:19 AM EDT

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Showing 217–240 of 781 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Bloodstream Infection Clear all
Completed Phase 3 Interventional

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

NCT00334828
View directory record Official record
Conditions
Severe Sepsis
Interventions
eritoran tetrasodium, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
69
States / cities
Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 66 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Oct 22, 2026, 2:19 AM EDT
Enrolling by invitation No phase listed Observational

EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 3)

NCT06160349
View directory record Official record
Conditions
Maternal Sepsis, Infections
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Rapid Identification and Susceptibility Testing of Pathogens From Blood Cultures

NCT01898208
View directory record Official record
Conditions
Bacteremia, Fungemia, Bloodstream Infection
Interventions
FilmArray testing, Antimicrobial Stewardship, Bacterial culture, Susceptibility testing
Device · Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
Up to 99 Years
Enrollment
743 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Oct 22, 2026, 2:19 AM EDT
Not listed No phase listed Observational

A Biologic Validation of Biomarkers of Progressive NEC & Sepsis

NCT00588718
View directory record Official record
Conditions
Necrotizing Enterocolitis
Interventions
Not listed
Lead sponsor
R. Lawrence Moss
Other
Eligibility
72 Hours to 28 Weeks
Enrollment
740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 22, 2026, 2:19 AM EDT
Active, not recruiting Not applicable Interventional

Dialysis Catheter Caps Case Feasibility Study

NCT06905080
View directory record Official record
Conditions
Sterile Catheter, Catheter-related Bloodstream Infections, Dialysis Catheter, Dialysis
Interventions
Catheter Caps Case (C3)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients

NCT02327130
View directory record Official record
Conditions
Sepsis
Interventions
Isomark Canary™
Device
Lead sponsor
Isomark, LLC
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Gainesville, Florida • Jacksonville, Florida • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Oct 22, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Novel Mechanisms and Approaches to Treat Neonatal Sepsis

NCT02554630
View directory record Official record
Conditions
Complication of Prematurity, Immunologic Deficiency Syndromes
Interventions
Adjuvant, Blood Collection
Other
Lead sponsor
University of Florida
Other
Eligibility
Up to 55 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 22, 2026, 2:19 AM EDT
Active, not recruiting No phase listed Observational

Correlating MicroRNA Changes With Sepsis Outcomes

NCT03929159
View directory record Official record
Conditions
Septicemia
Interventions
Biospecimen Collection
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Phase 1 Interventional

The Effects of HIV Protease Inhibitors in Severe Sepsis

NCT00346580
View directory record Official record
Conditions
Sepsis
Interventions
Nelfinavir
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 5, 2011 · Synced Oct 22, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

NCT06614309
View directory record Official record
Conditions
Long COVID
Interventions
Acute Placebo Visit, Acute Progressive Carbon Dioxide, Acute Intermittent Hypoxia, Training: Progressive Carbon Dioxide Ramping, Training: Intermittent Hypoxic Exposure, Training: Placebo Control
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Not listed Not applicable Interventional

Timing of Acute Palliative Care Consultation in Critically Ill Patients

NCT02858778
View directory record Official record
Conditions
Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5, Hepatic Encephalopathy, Sepsis, Dementia, Multiple Sclerosis, Parkinson's Disease, In-Hospital Cardiac Arrest, Solid Organ Cancer
Interventions
Early order of palliative care consultation
Other
Lead sponsor
Wayne State University
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2016
U.S. locations
2
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Oct 22, 2026, 2:19 AM EDT
Terminated Phase 1 Interventional Results available

Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)

NCT04870125
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Sepsis
Interventions
Inhaled Carbon Monoxide at CFK equation-determined personalized dose (200-500 ppm to achieve a COHb level of 6-8%), Inhaled Medical air
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postpartum Video Education

NCT05159726
View directory record Official record
Conditions
Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression, Patient Empowerment, Patient Education, Postpartum Care
Interventions
Video Education
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Evaluating Artificial Intelligence-Based Clinical Decision Support for Sepsis and ARDS

NCT07025096
View directory record Official record
Conditions
Sepsis, Acute Respiratory Distress Syndrome (ARDS)
Interventions
Artifical Intelligence-Generated Treatment Recommendations
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Results available

Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis

NCT01739361
View directory record Official record
Conditions
Severe Sepsis
Interventions
Acetaminophen, placebo
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 26, 2017 · Synced Oct 22, 2026, 2:19 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Recovery of Physical Function After Critical Illness In Older Adults

NCT07225257
View directory record Official record
Conditions
Sepsis, Acute Lung Injury(ALI)
Interventions
Not listed
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Terminated Phase 1 Interventional

Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis

NCT02576457
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
BMS-936559, Placebo
Biological · Other
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
13
States / cities
Sacramento, California • Denver, Colorado • Gainesville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 22, 2026, 2:19 AM EDT
Terminated Phase 3 Interventional Results available

Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis

NCT00815516
View directory record Official record
Conditions
Candidiasis
Interventions
micafungin, amphotericin B deoxycholate
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
48 Hours to 120 Days
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
5
States / cities
Orange, California • New Brunswick, New Jersey • Durham, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2015 · Synced Oct 22, 2026, 2:19 AM EDT
Terminated Phase 2 Interventional Results available

High Dose Intravenous Ascorbic Acid in Severe Sepsis

NCT02734147
View directory record Official record
Conditions
Sepsis
Interventions
Ascorbic Acid, Normal Saline
Drug · Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 22, 2026, 2:19 AM EDT
Completed No phase listed Observational

Fluconazole Pharmacokinetics in Infants

NCT00514358
View directory record Official record
Conditions
Fungal Infection
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 119 Days
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
5
States / cities
Detroit, Michigan • Philadelphia, Pennsylvania • Houston, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2011 · Synced Oct 22, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

NCT03992378
View directory record Official record
Conditions
Septic Shock
Interventions
Low Level Transcutaneous Vagus Nerve Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 22, 2026, 2:19 AM EDT
Terminated Not applicable Interventional

EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock

NCT04134624
View directory record Official record
Conditions
Sepsis, Sepsis, Severe, Septic Shock
Interventions
Sepsis care bundle
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 100 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Stillwater, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Results available

Esmolol Infusion for Patients With Septic Shock and Persistent Tachycardia

NCT02841241
View directory record Official record
Conditions
Septic Shock
Interventions
Esmolol
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 22, 2026, 2:19 AM EDT
Completed Phase 2 Interventional Results available

Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients

NCT01321879
View directory record Official record
Conditions
Infection, Bacteremia
Interventions
Telavancin
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2019 · Synced Oct 22, 2026, 2:19 AM EDT