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ClinicalTrials.gov public records Last synced Oct 25, 2026, 3:20 AM EDT

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Showing 25–48 of 287 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Body Temperature Changes Clear all
Terminated Early Phase 1 Interventional

Maternal Epidural Steroids and Hyperthemia

NCT02212210
View directory record Official record
Conditions
Fever, Labor Pain, Complication of Anesthesia During Pregnancy, Unspecified
Interventions
Methylprednisolone, Normal saline
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Pomegranate Products for Prevention of Common Cold

NCT00617318
View directory record Official record
Conditions
Influenza, Common Cold, Cough, Headache, Fever
Interventions
Pomegranate, Placebo
Dietary Supplement
Lead sponsor
Texas Heart Institute
Other
Eligibility
21 Years to 49 Years
Enrollment
461 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2008 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intraoperative Warming Comparison of Devices

NCT00650260
View directory record Official record
Conditions
Hypothermia
Interventions
Dynatherm Medical vitalHEAT Temperature Management System vH2, Bair Hugger™ (Arizant Healthcare, Eden Prairie, MN)
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 29, 2012 · Synced Oct 25, 2026, 3:20 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy

NCT03129620
View directory record Official record
Conditions
Hypothermia
Interventions
Not listed
Lead sponsor
Drexel University
Other
Eligibility
6 Hours to 24 Hours
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Oct 25, 2026, 3:20 AM EDT
Terminated Not applicable Interventional Results available

Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)

NCT01192776
View directory record Official record
Conditions
Infant, Newborn, Hypoxia, Brain, Hypoxia-Ischemia, Brain, Encephalopathy, Hypoxic-Ischemic, Hypoxic-Ischemic Encephalopathy, Ischemic-Hypoxic Encephalopathy
Interventions
Whole-body Cooling
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 6 Hours
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 25, 2026, 3:20 AM EDT
Terminated Not applicable Interventional Results available

Harmonic Scalpel Vs. Electrocautery in Breast Reduction Surgery

NCT00819260
View directory record Official record
Conditions
Hyperplasia
Interventions
Harmonic Scalpel, Electrocautery
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 20, 2013 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Caffeinol Hypothermia Protocol

NCT00299416
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Caffeinol, hypothermia
Drug · Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2011 · Synced Oct 25, 2026, 3:20 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults

NCT06842784
View directory record Official record
Conditions
Aging, Heat Stress, Hyperthermia, Heat Strain
Interventions
Ambient heat stress
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 25, 2026, 3:20 AM EDT
Completed No phase listed Observational

Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients

NCT03262584
View directory record Official record
Conditions
Invasive Fungal Disease, Fever and Neutropenia, Invasive Fungal Infections, Immunocompromised
Interventions
Not listed
Lead sponsor
Karius, Inc.
Industry
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction

NCT00986453
View directory record Official record
Conditions
Macromastia
Interventions
PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
Device · Procedure
Lead sponsor
Medtronic Surgical Technologies
Industry
Eligibility
20 Years to 60 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
7
States / cities
Burbank, California • Glendale, California • Mountain View, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2013 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Intranasal Cocaine and Temperature Regulation During Exercise

NCT05809453
View directory record Official record
Conditions
Hyperthermia, Cocaine Use, Exercise
Interventions
Cocaine, Lidocaine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Oct 25, 2026, 3:20 AM EDT
Recruiting Not applicable Interventional

Remote Temperature Monitoring of Patients At Risk for Developing Fever

NCT06752512
View directory record Official record
Conditions
Fever, Cancer, Remote Patient Monitoring
Interventions
Remote Patient Monitoring
Device
Lead sponsor
AION Biosystems
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Schenectady, New York
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 4 Interventional Results available

Temperature Control in Central Fever in the Neuro-ICU

NCT00751634
View directory record Official record
Conditions
Fever, Brain Hemorrhage
Interventions
Gaymar Rapr-Round (external cooling blanket)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Oct 25, 2026, 3:20 AM EDT
Withdrawn No phase listed Observational

A Case Control Study of Patients With Diagnosis of Malignant Hyperthermia

NCT02561598
View directory record Official record
Conditions
Malignant Hyperthermia
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 15, 2022 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Results available

Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.

NCT03697122
View directory record Official record
Conditions
Hypothermia, Rewarming
Interventions
Heated Humidified Breathing Circuit and Forced Air Blanket
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord

NCT01707095
View directory record Official record
Conditions
Fatigue
Interventions
Unbundling of cords, Bundling of cords
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 17, 2014 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room

NCT00904228
View directory record Official record
Conditions
Hypothermia
Interventions
placement of plastic cap during delivery room stabilization, placement of routine cap during delivery room stabilization
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 1 Hour
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients

NCT03896867
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Anapod™ Humi-Therm Heated Humidification System Breathing Circuit, Bair Hugger™ Warming Blanket
Device
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 18 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 1 Interventional

A Phase I Study of Isolated Hepatic Portal and Arterial Perfusion (IHP) With Escalating Dose Melphalan for Primary or Metastatic Unresectable Cancers of the Liver

NCT00001587
View directory record Official record
Conditions
Liver Neoplasms, Neoplasm Metastasis
Interventions
Isolated hepatic portal and arterial perfusion, Melphalan
Procedure · Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Post-Procedural Biotech Cellulose Mask

NCT06065332
View directory record Official record
Conditions
Temperature Change, Body
Interventions
Velez Intense Hydration Mask® (biotech cellulose face mask)
Other
Lead sponsor
Siperstein Dermatology
Other
Eligibility
22 Years to 100 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional

Caspofungin Acetate in Treating Children With Fever and Neutropenia

NCT00020527
View directory record Official record
Conditions
Fever, Sweats, and Hot Flashes, Infection, Kidney Cancer, Leukemia, Lymphoma, Neuroblastoma, Neutropenia, Sarcoma
Interventions
caspofungin acetate
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
2 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Bethesda, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Water Bolus Volumes During Continuous Exercise in Heat

NCT04613856
View directory record Official record
Conditions
Dehydration (Physiology), Hyperthermia
Interventions
Hydration protocol - 237 mL water bolus, Hydration protocol - 500 mL water bolus
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Not applicable Interventional

Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures

NCT00521729
View directory record Official record
Conditions
Obesity
Interventions
Exposure to Cold Temperature
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 25, 2026, 3:20 AM EDT
Completed Phase 3 Interventional Results available

PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study

NCT00911170
View directory record Official record
Conditions
Cancer, Colon Cancer, Colorectal Cancer, Fever, Locally Advanced, Metastatic Colorectal Cancer, Neutropenia, Rectal Cancer
Interventions
Pegfilgrastim, Placebo, Bevacizumab, Standard Chemotherapy
Drug · Biological
Lead sponsor
Amgen
Industry
Eligibility
18 Years and older
Enrollment
847 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
72
States / cities
Muscle Shoals, Alabama • Jonesboro, Arkansas • Anaheim, California + 66 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2017 · Synced Oct 25, 2026, 3:20 AM EDT