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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:50 AM EDT

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Showing 73–96 of 6,934 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Body Weight Clear all
Active, not recruiting Phase 2 Interventional

A Study of the Body's Response to Exercise and a Plant-Based Diet in Overweight Postmenopausal Women With Breast Cancer

NCT04298086
View directory record Official record
Conditions
Breast Cancer, Primary Hormone Receptor Positive Breast Cancer
Interventions
Exercise Treatment, Plant-Based Diet, Physical activity, Nutrition counseling, Replication Exercise Test
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Muscle Protein Metabolism in Obesity

NCT01824173
View directory record Official record
Conditions
Obesity
Interventions
Increase in the levels of plasma amino acids, Aerobic exercise
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Commercial Program on Weight Loss and Health Outcomes

NCT03928483
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Modified WW Food program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Exergaming: A Research Study Testing a Videogame Intervention to Increase Physical Activity for Families

NCT00889122
View directory record Official record
Conditions
Obesity
Interventions
Exergame (DDR)
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
9 Years to 17 Years
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Scarborough, Maine
Source: ClinicalTrials.gov public record
Updated Aug 4, 2010 · Synced Oct 20, 2026, 5:50 AM EDT
Withdrawn No phase listed Observational

Effect of Lap-Band Induced Weight Loss on Serum PSA Levels

NCT00562341
View directory record Official record
Conditions
Obesity, Prostate Cancer
Interventions
Bariatric Surgery
Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
20 Years to 60 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Vitamin D Supplementation in Psychiatric Illnesses

NCT01004354
View directory record Official record
Conditions
Obesity, Vitamin D Deficiency, Psychosis, Schizophrenia, Schizoaffective Disorder
Interventions
Ergocalciferols
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
10 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 20, 2026, 5:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention

NCT03950453
View directory record Official record
Conditions
Child Obesity
Interventions
Parenting Mindfully for Health Nutrition (PMH), Contact Control Nutrition (C+N), Non-randomized historical control (WLC) assessment only
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
2 Years to 5 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 20, 2026, 5:50 AM EDT
Not yet recruiting Not applicable Interventional

Digitally Enhanced Cognitive-Behavioral Therapy

NCT07569991
View directory record Official record
Conditions
Depression in Adolescence, Obesity & Overweight, Cognitive-behavioral Therapy, Mobile Health Technology (mHealth), Health Behavior
Interventions
Cognitive-behavioral therapy (CBT), Digital app
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PROphylactic Wound VACuum Therapy to Decrease Rates of Cesarean Section in the Obese Population

NCT02128997
View directory record Official record
Conditions
Wound Complication
Interventions
Closed incision wound vacuum (Prevena)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2017 · Synced Oct 20, 2026, 5:50 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

NCT02400359
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Lorcaserin HCl, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prepackaged Foods to Promote Weight Loss

NCT02136290
View directory record Official record
Conditions
Overweight, Obese
Interventions
Prepackaged meals, Usual Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
25 Years to 65 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2015 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Safety and Efficacy of Laparoscopic Truncal Vagotomy for the Treatment of Obesity

NCT00285220
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic Truncal Vagotomy
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
25 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
San Francisco, California • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2009 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Independent Weight Loss Maintenance for Communities With Arthritis in North Carolina: the I-CAN Clinical Trial

NCT03832296
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Weight-Loss Maintenance, Health Education (Attention Control)
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
51 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Chapel Hill, North Carolina • Clyde, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 20, 2026, 5:50 AM EDT
Completed No phase listed Observational

A Study to Characterize the Prevalence of Overweight and Obesity Among Patients With Established Cardiovascular Disease

NCT05873660
View directory record Official record
Conditions
Obesity, Overweight
Interventions
No treatment given
Other
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
5,360 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Plainsboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 2 Interventional

Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants

NCT00818220
View directory record Official record
Conditions
Intraventricular Hemorrhage, Sepsis
Interventions
delayed umbilical cord clamping, Immediate cord clamping
Procedure · Other
Lead sponsor
University of Rhode Island
Other
Eligibility
Not listed
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 20, 2026, 5:50 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Etiological Factors of Obesity-Associated Hyperandrogenemia in Peripubertal Girls

NCT00928759
View directory record Official record
Conditions
Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
8 Years to 16 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2023
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or Obesity

NCT07400679
View directory record Official record
Conditions
Overweight, Obesity, Healthy
Interventions
PF-08653944
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 1 Interventional

Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS

NCT00000646
View directory record Official record
Conditions
HIV Infections
Interventions
Pentoxifylline
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 1993
U.S. locations
2
States / cities
Boston, Massachusetts • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 1 Interventional Results available

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

NCT04478708
View directory record Official record
Conditions
Obesity
Interventions
maridebart cafraglutide, Placebo
Biological · Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Anaheim, California • Tustin, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional

A Trial of Two Diets for Weight and Diabetes Management

NCT00729196
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Lifestyle Modification
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 1, 2011 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Maintenance-Tailored Obesity Treatment

NCT00670462
View directory record Official record
Conditions
Obesity
Interventions
Standard Behavioral Treatment (SBT), Maintenance-Tailored Treatment (MTT)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 20, 2026, 5:50 AM EDT
Completed Phase 3 Interventional Results available

Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity

NCT04074161
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Semaglutide, Placebo (semaglutide), Liraglutide, Placebo (liraglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
19
States / cities
Birmingham, Alabama • Fullerton, California • Huntington Beach, California + 15 more
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 20, 2026, 5:50 AM EDT
Active, not recruiting Phase 1 Interventional

A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet

NCT07184086
View directory record Official record
Conditions
Obesity
Interventions
CagriSema (Cagrilintide B + semaglutide I), Low Energy Diet
Drug · Behavioral
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Orlando, Florida • Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 5:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Elements Vital to Treat Obesity Study

NCT04708769
View directory record Official record
Conditions
Obesity
Interventions
Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 20, 2026, 5:50 AM EDT