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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Bone Augmentation Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Guided Bone Regeneration With and Without the Use of Intra-marrow Penetrations

NCT06353399
View directory record Official record
Conditions
Ridge Augmentation
Interventions
Intra-marrow penetrations, No Intra-marrow penetrations
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Histomorphometric Analysis Following Sinus Augmentation Using Two Different Bone Graft Materials.

NCT03059914
View directory record Official record
Conditions
Missing Teeth
Interventions
InterOss, Bio-oss
Device
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 103 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Not yet recruiting No phase listed Observational

Outcomes of Different Bone Graft Combinations for Maxillary Sinus Augmentation Procedure

NCT07512011
View directory record Official record
Conditions
Bone Grafting, Sinus Lifting
Interventions
Bone grafting on both sides
Device
Lead sponsor
Ohio State University
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Terminated Phase 3 Interventional Results available

Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® System

NCT01011816
View directory record Official record
Conditions
Back Pain, Chronic Low Back Pain, Internal Disc Disruption, Degenerative Disc Disease
Interventions
BIOSTAT BIOLOGX, Saline
Biological · Drug
Lead sponsor
Spinal Restoration, Inc.
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Chula Vista, California + 17 more
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Comparing Two Surgical Techniques for Building up the Bone Where a Dental Implant is to be Placed

NCT06871657
View directory record Official record
Conditions
Dental Implant, Sinus Floor Augmentation
Interventions
Sinus lift using osseodensification technique, Sinus lift using the osseocondensation technique
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers Results available

Comparing the Efficacy and Morbidity of Two Vertical Ridge Augmentation Techniques

NCT02703480
View directory record Official record
Conditions
Vertical Alveolar Bone Loss
Interventions
d-PTFE, Ti-mesh
Biological
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Compare Different Soft Tissue Grafts at the Time of Lateral Ridge Augmentation Procedure.

NCT03774888
View directory record Official record
Conditions
Bone Graft; Complications, Infection or Inflammation, Ridge Deficency, Dental Implant
Interventions
Connective tissue graft at time of bone graft, Acellular Demal Matrix at time of bone graft, No soft tissue grafting at time of bone graft
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Bone Tissue Engineering Using Autologous Bone Repair Cell (BRC) Therapy for Sinus Floor Bone Augmentation

NCT00980278
View directory record Official record
Conditions
Tooth Loss
Interventions
Sinus lift augmentation and dental implant, Aastrom BRCs
Procedure · Biological
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 22, 2015 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Intervertebral Disc Augmentation With Minimally Invasive Surgical Procedure

NCT01442922
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
completion of the (VAS) for level of back pain, completion of the (OLBPQ) for assessment of function
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 44 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft

NCT02154386
View directory record Official record
Conditions
Bone Augmentation
Interventions
Ridge preservation using DFDBA
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone

NCT07090122
View directory record Official record
Conditions
Spine Metastases, Bone Pain
Interventions
Radiofrequency ablation and bone augmentation with radiotherapy, Radiotherapy alone
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Phase 3 Interventional

Biologic Augmentation of TMJ Arthroscopy Using BMAC

NCT07536399
View directory record Official record
Conditions
TMJ - Oral &Maxillofacial Surgery, Oral and Maxillofacial Conditions, TMJ Pain, TMJ Arthralgia
Interventions
Bone Marrow Aspirate Concentrate, Corticosteroid (CS)
Biological · Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Free Gingival Graft Timing

NCT06294587
View directory record Official record
Conditions
Ridge Augmentation, Alveolar Mucosa
Interventions
FGG Before GBR, FGG after GBR
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Recruiting Not applicable Interventional

HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

NCT06011551
View directory record Official record
Conditions
Degenerative Disc Disease (DDD)
Interventions
The ReGelTec HYDRAFIL™ System, Conservative Care Management
Device · Other
Lead sponsor
ReGelTec, Inc.
Industry
Eligibility
22 Years to 85 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
14
States / cities
Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional

Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients

NCT00933036
View directory record Official record
Conditions
Pathologic Fracture of the Vertebra Due to Osteoporosis
Interventions
Crosstrees Pod system for PVA
Device
Lead sponsor
Crosstrees Medical Inc.
Industry
Eligibility
50 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
9
States / cities
Long Beach, California • Washington D.C., District of Columbia • Clearwater, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2014 · Synced Sep 5, 2026, 2:15 PM EDT
Completed No phase listed Observational

Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis

NCT01839682
View directory record Official record
Conditions
Osteoporosis, Vertebral Fracture
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
50 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2013 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Bone Material Comparison in Maxillary Sinus Augmentation

NCT04433117
View directory record Official record
Conditions
Alveolar Bone Resorption, Sequela, Tooth Extrusion
Interventions
Shefabone, Bio-Oss
Biological
Lead sponsor
Mohanad Al-Sabbagh
Other
Eligibility
20 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis

NCT00290862
View directory record Official record
Conditions
Spinal Fractures
Interventions
Percutaneous Vertebral Augmentation of compression fractures
Device
Lead sponsor
Orthovita d/b/a Stryker
Industry
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
18
States / cities
Scottsdale, Arizona • Encinitas, California • Rancho Mirage, California + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2008 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges

NCT03468998
View directory record Official record
Conditions
Alveolar Ridge Augmentation, Alveolar Ridge Preservation
Interventions
Socket Grafting with small particle allograft, Socket Grafting with large particle allograft, Lateral ridge augmentation with small particle allograft, Lateral ridge augmentation with large particle allograft
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Sep 5, 2026, 2:15 PM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Space Maintenance Devices

NCT00991432
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 5, 2026, 2:15 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

NCT07613047
View directory record Official record
Conditions
Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
Interventions
Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Volumetric Changes and Graft Stability in Lateral Window Sinus Augmentation: A Prospective Clinical Trial

NCT03639077
View directory record Official record
Conditions
Lateral Window Sinus Augmentation
Interventions
Allograft bone alone, Allograft and xenograft mixture
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 5, 2026, 2:15 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Ridge Augmentation Comparing a Block Allograft to a Demineralized Bone Matrix Allograft.

NCT02127112
View directory record Official record
Conditions
Alveolar Process Defect
Interventions
Block Allograft plus Matrix Allograft, Moldable Matrix Allograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 5, 2026, 2:15 PM EDT