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ClinicalTrials.gov public records Last synced Oct 27, 2026, 5:38 PM EDT

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Showing 793–816 of 976 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Bone Injuries Clear all
Completed Not applicable Interventional

A Prospective Study to Determine the Effectiveness of Reaming in Reducing Fat Emboli to the Lungs

NCT00327158
View directory record Official record
Conditions
Diaphyseal Femur Fracture
Interventions
Transesophageal transducer, echocardiography
Procedure
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 28, 2010 · Synced Oct 27, 2026, 5:38 PM EDT
Terminated Not applicable Interventional Results available

Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia

NCT01430182
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Methadone, Morphine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Not applicable Interventional Results available

Functional Status, Morbidity and Mortality in Cemented Versus Press-Fit Hemiarthroplasty

NCT01114646
View directory record Official record
Conditions
Femoral Neck Fracture
Interventions
Cemented Hip Hemiarthroplasty, VerSys Beaded FullCoat, Zimmer
Device
Lead sponsor
Hartford Hospital
Other
Eligibility
55 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Oct 27, 2026, 5:38 PM EDT
Recruiting Phase 3 Interventional

Intramedullary Calcium Sulfate Antibiotic Depot

NCT05766670
View directory record Official record
Conditions
Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures
Interventions
Vancomycin Hydrochloride, Gentamicin, Standard Intramedullary Nail
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
12
States / cities
Los Angeles, California • Macon, Georgia • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Recruiting No phase listed Observational

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

NCT06883396
View directory record Official record
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Active, not recruiting Phase 1 Interventional

BM-MNCs for Lower Extremity Compartment Syndrome Injury

NCT03880656
View directory record Official record
Conditions
Compartment Syndrome Traumatic Lower Extremity
Interventions
Intramuscular administration of autologous BM-MNCs
Biological
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Early Phase 1 Interventional

NSAIDS Versus Opioids in Acute SER II Ankle Fractures

NCT02373254
View directory record Official record
Conditions
Ankle Fracture
Interventions
Ibuprofen, Acetaminophen/hydrocodone
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2017 · Synced Oct 27, 2026, 5:38 PM EDT
Completed No phase listed Observational Results available

ICG 24h Prior to Operative Treatment of Orthopaedic Infection

NCT04927637
View directory record Official record
Conditions
Trauma Injury, Bone Infection
Interventions
imaging 24 hours following intravenous administration of ICG
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Phase 4 Interventional

Efficacy of Hematoma Block on Postoperative Pain After Femoral Intramedullary Rodding: A Randomized Trial

NCT04860856
View directory record Official record
Conditions
Femur Fracture
Interventions
0.5% ropivacaine, Normal Saline
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 27, 2026, 5:38 PM EDT
Withdrawn Not applicable Interventional

Dialectical Behavioral Therapy in High Risk OrthopaedicTrauma Patients

NCT03776929
View directory record Official record
Conditions
Fracture, Surgery
Interventions
Dialectical Behavioral Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 27, 2026, 5:38 PM EDT
Withdrawn Not applicable Interventional

Custom Dynamic Orthoses to Reduce Articular Contact Stress

NCT05209347
View directory record Official record
Conditions
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Active, not recruiting No phase listed Observational

Inflammatory Response Following Intraarticular Fracture

NCT01514643
View directory record Official record
Conditions
Intraarticular Fracture and Post-traumatic Osteoarthritis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Not applicable Interventional

Study of Tibial Shaft Fractures in Children

NCT01238523
View directory record Official record
Conditions
Tibial Shaft Fractures in Children
Interventions
Long leg cast in full extension, Long leg cast with 45 degrees of flexion
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Years to 14 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 27, 2026, 5:38 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Use of Complementary and Alternative Medicine Among Older Mexican Americans

NCT00084110
View directory record Official record
Conditions
Arthritis, Diabetes Mellitus, Fractures, Hypertension, Depression, Urinary Incontinence
Interventions
Not listed
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
65 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1993 – 2000
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 27, 2026, 5:38 PM EDT
Completed No phase listed Observational

Timing of Orthopaedic Surgery in the Multiply-injured Patient: Development of a Protocol for Early Appropriate Care

NCT00888160
View directory record Official record
Conditions
Unstable Pelvic Ring Fracture, Unstable Acetabulum Fracture, Femur Fracture
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
16 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Phase 2 Interventional Results available

IN Sub-Dissociative Ketamine vs IN Fentanyl

NCT02521415
View directory record Official record
Conditions
Bone Fracture
Interventions
ketamine, fentanyl, ibuprofen or acetaminophen
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
4 Years to 17 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 27, 2026, 5:38 PM EDT
Active, not recruiting Phase 4 Interventional

Romosozumab Use to Build Skeletal Integrity

NCT05058976
View directory record Official record
Conditions
Osteoporosis, Osteoporosis, Postmenopausal, Osteoporosis Fracture
Interventions
Romosozumab, Placebo, Zoledronic acid, Calcium and Vitamin D
Drug · Dietary Supplement
Lead sponsor
Susan L. Greenspan
Other
Eligibility
65 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Phase 3 Interventional

PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2

NCT03582176
View directory record Official record
Conditions
Elbow Fracture, Elbow Injury, Elbow Dislocation
Interventions
Lactose Placebo, Ketotifen Fumarate 2mg, Ketotifen Fumarate 5mg
Drug
Lead sponsor
University of Calgary
Other
Eligibility
18 Years to 95 Years
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Baltimore, Maryland • Charlotte, North Carolina • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Terminated Phase 1 Interventional

The Erector Spinae Plane Block and Its Effect on Respiratory Status and Pain Management in Rib Fracture Patients

NCT03805360
View directory record Official record
Conditions
Rib Fractures
Interventions
Ropivacaine, Normal Saline Flush, 0.9% Injectable Solution
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Oct 27, 2026, 5:38 PM EDT
Enrolling by invitation No phase listed Observational

Tornier HRS (Humeral Reconstruction System) Study (REVIVE)

NCT05500066
View directory record Official record
Conditions
Rheumatoid Arthritis, Osteoarthritis Shoulder, Fractures Humerus, Avascular Necrosis, Correction of Functional Deformity, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains, Rotator Cuff Tears
Interventions
Tornier HRS (HUMERAL RECONSTRUCTION SYSTEM) shoulder system
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2036
U.S. locations
4
States / cities
Denver, Colorado • Bradenton, Florida • Tampa, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Not yet recruiting Phase 4 Interventional

Prospective Study: TXA, Anticoagulant, Orthopaedic Trauma

NCT07116395
View directory record Official record
Conditions
Patients Undergoing Operative Fixation of Long Bone Fractures Within the Community Medical Centers System
Interventions
Tranexamic Acid (TXA)
Drug
Lead sponsor
Arbi Nazarian, MD
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Enrolling by invitation Not applicable Interventional

Evaluating the Effectiveness of Remote Monitoring for Post-Operative Management of Distal Radius Fractures

NCT07219979
View directory record Official record
Conditions
Distal Radius Fracture, Distal Radius Fracture Fixation
Interventions
Remote Monitoring Follow-Up, Standard In-Person Follow-Up
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 27, 2026, 5:38 PM EDT
Terminated Not applicable Interventional

Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques

NCT02845245
View directory record Official record
Conditions
Tibial Fractures
Interventions
3D printed plastic model prototype, 3D CT scan, Plain film radiographs
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 27, 2026, 5:38 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient Activation After DXA Result Notification

NCT01507662
View directory record Official record
Conditions
Osteoporosis, Bone Diseases, Metabolic
Interventions
Bone Mineral Density Result Letter and Bone Health Brochure
Behavioral
Lead sponsor
Fredric D Wolinsky
Other
Eligibility
50 Years and older
Enrollment
7,749 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
3
States / cities
Birmingham, Alabama • Atlanta, Georgia • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 27, 2026, 5:38 PM EDT