Independent directory Public ClinicalTrials.gov records United States
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Showing 289–312 of 369 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Accepts healthy volunteers

Treatment of Calcium Deficiency in Young Women

NCT00000426
Conditions
Osteoporosis
Interventions
Calcium supplement
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 27 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2000
U.S. locations
1
States / cities
Omaha, Nebraska
Completed No phase listed Observational

Bone MicroArchitecture in Acromegaly

NCT03225040
Conditions
Acromegaly, Osteoporosis Risk
Interventions
Pegvisomant
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Accepts healthy volunteers

A Preliminary Study of Bone Density in Neonates

NCT00631397
Conditions
Osteopenia Of Prematurity
Interventions
Ultrasound machine
Device
Lead sponsor
University of South Florida
Other
Eligibility
24 Weeks to 33 Weeks
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Weight Loss and Dietary Protein Intake on Bone

NCT00473031
Conditions
Weight Loss, Bone Density
Interventions
Caloric restriction, high protein, Caloric restriction; normal protein, Counseling
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Cerebral Palsy
Interventions
High frequency, low magnitude vibration, Standing
Device · Other
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
6 Years to 12 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Bone Density, Bone Loss, Anorexia Nervosa, Eating Disorder, Atypical Anorexia Nervosa
Interventions
Denosumab 60 MG [Prolia], Placebo Injection, Alendronate 70Mg Tab
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Interventions
Romosozumab, Denosumab, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Completed No phase listed Observational Accepts healthy volunteers

Bone Mineral Accretion in Young Children

NCT02162602
Conditions
Bone Mineral Density Reference Data
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Year to 5 Years
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
2
States / cities
Cincinnati, Ohio • Philadelphia, Pennsylvania
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Bone Mass Accrual in Adolescent Athletes

NCT00827151
Conditions
Amenorrhea, Bone Loss
Interventions
Estrogen
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 21 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Prostate Cancer, Osteoporosis, Hypogonadism
Interventions
alendronate
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
50 Years to 85 Years · Male only
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Phase 3 Interventional Results available

Zoledronic Acid in Acute Spinal Cord Injury

NCT01642901
Conditions
Spinal Cord Injury
Interventions
Zoledronic acid, normal saline 0.9%
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Osteopenia
Interventions
resistance exercise, plyometric exercise
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
25 Years to 60 Years · Male only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
HIV Infections, Heart Disease
Interventions
Rosuvastatin 10 mg. daily for 96 weeks, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Infection, Human Immunodeficiency Virus
Interventions
Triumeq
Drug
Lead sponsor
Mills Clinical Research
Industry
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Diabetes Mellitus, Type 2
Interventions
Rosiglitazone, Metformin
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
55 Years to 80 Years · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
21
States / cities
Tucson, Arizona • Huntington Park, California • Los Angeles, California + 15 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA

NCT06659055
Conditions
Healthy, Indicated for EOSedge Imaging
Interventions
DXA Imaging, EOSedge imaging
Radiation
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
20 Years and older
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Phoenix, Arizona • Carlsbad, California • Memphis, Tennessee + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Improving Bone Health in Adolescence Through Targeted Behavioral Intervention

NCT02202889
Conditions
Bone Development, Dietary Adequacy
Interventions
Adequate Calcium Today
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
10 Years to 13 Years · Female only
Enrollment
848 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
West Lafayette, Indiana
Completed No phase listed Observational Accepts healthy volunteers

Type 1 Diabetes Mellitus Effect on Bone Mineral Density

NCT01633684
Conditions
Diabetes Mellitus, Osteoporosis
Interventions
Not listed
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 50 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Completed Not applicable Interventional Accepts healthy volunteers

Resveratrol for the Prevention of Bone Loss in Postmenopausal Women

NCT06250283
Conditions
Low Bone Mass
Interventions
Resveratrol, Placebo
Dietary Supplement
Lead sponsor
University of Delaware
Other
Eligibility
Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effects of Anorexia Nervosa on Peak Bone Mass

NCT01301183
Conditions
Anorexia Nervosa
Interventions
RhIGF-1 with transdermal 17-beta estradiol, Placebo and transdermal 17-beta estradiol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 22 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Study of Heritable Connective Tissue Disorders

NCT00001641
Conditions
Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome, Nail Patella Syndrome
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

"VIBES"--Low Magnitude Mechanical Stimulation to Improve Bone Mineral Density

NCT00396994
Conditions
Osteopenia
Interventions
Low magnitude mechanical stimulation, Sham low magnitude mechanical stimulation
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Effect of Thiazolidinediones on Human Bone

NCT00927355
Conditions
Osteoblast, Adipocytes, Bone Density, Osteocalcin, Adiponectin, Mesenchymal Stem Cells
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers Results available

VITamin D and OmegA-3 TriaL: Effects on Bone Structure and Architecture (VITAL)

NCT01747447
Conditions
Bone Density, Body Composition, Bone Health
Interventions
Vitamin D3 placebo, Fish oil placebo, omega-3 fatty acids (fish oil), Vitamin D3
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years and older
Enrollment
771 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts