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ClinicalTrials.gov public records Last synced Nov 11, 2026, 7:22 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 467 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Bone Pain Clear all

Conditions: Degenerative Disc Disease, Low Back Pain, Disc Degeneration
Interventions: VIA Disc NP; Other
Lead sponsor: VIVEX Biologics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 6
States / cities: Larkspur, California • Santa Monica, California • Walnut Creek, California + 3 more

Conditions: Hematologic Malignancy
Interventions: Standard of Care, Virtual Reality intervention; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: zoledronic acid, quality-of-life assessment; Drug · Procedure
Lead sponsor: Novartis; Industry
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2001
U.S. locations: 55
States / cities: Birmingham, Alabama • Springdale, Arkansas • Gilroy, California + 48 more

Conditions: Hypophosphatemia, Hypophosphatemic Rickets, Pain, Chronic
Interventions: Burosumab; Biological
Lead sponsor: Redwood Dermatology Sciences; Other
Eligibility: Up to 18 Years · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Clinton, Utah

Conditions: Rib Fractures, Pain Acute, Regional Anesthesia, Opioid Use
Interventions: Serratus Anterior Plane Block, Ropivacaine injection; Procedure · Drug
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
Interventions: Not listed
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 45 Years to 75 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
Interventions: Propranolol Hcl 40mg Tab, Placebo oral tablet; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Lumbar Degenerative Disc Disease
Interventions: PDS System, Fusion; Device
Lead sponsor: Interventional Spine, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Cincinnati, Ohio • Willow Grove, Pennsylvania

Conditions: Chronic Illness, Hematologic Malignancy, Bone Marrow Transplant Infection, Oncology, Sickle Cell Disease
Interventions: Guided Imagery, Virtual Reality; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 8 Years to 25 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Milwaukee, Wisconsin • Wauwatosa, Wisconsin

Conditions: Musculoskeletal Pain, Musculoskeletal Injury
Interventions: clinical examination, MRI; Diagnostic Test · Other
Lead sponsor: High Point University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: High Point, North Carolina

Conditions: Rib Fracture, Rib Fracture Multiple
Interventions: Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block; Device · Procedure
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 5
States / cities: La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more

Conditions: Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
Interventions: Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 80 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal, Intervertebral Disc Injury
Interventions: NSSD, Sham NSSD; Device
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years to 65 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Stanford, California • Tampa, Florida

Conditions: Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hematologic Malignancy
Interventions: Portomar(TM) Device; Device
Lead sponsor: Aperture Medical Technology, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Chronic Low Back Pain (CLBP), Intervertebral Disc Displacement
Interventions: Sustained Acoustic Medicine (SAM), Sham Device; Device
Lead sponsor: ZetrOZ, Inc.; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 3
States / cities: Dryden, New York • Chapel Hill, North Carolina • Ogden, Utah

Conditions: Distal Radius Fracture, Radius Fracture Distal, Radius; Fracture, Lower or Distal End, Postoperative Pain
Interventions: Vibration tool; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Fractures, Closed, Humeral Fractures, Pain
Interventions: Ropivacaine, Puncture Wound and Dressing; Drug · Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 4 Years to 12 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Joint Discomfort, Wellbeing, Quality of Life
Interventions: Undenatured collagen, Whole salmon oil; Dietary Supplement
Lead sponsor: Hofseth Biocare ASA; Industry
Eligibility: 40 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Post Operative Pain, Distal Radius Fracture
Interventions: Dexamethasone 4mg, Ropivacaine; Drug
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Bone Marrow Edema, Knee Osteoarthritis, Knee Pain Chronic
Interventions: Focused extracorporeal shockwave therapy; Device
Lead sponsor: Kessler Foundation; Other
Eligibility: 30 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Cedar Knolls, New Jersey • West Orange, New Jersey

Conditions: Herniated Disc, Low Back Pain
Interventions: Diskectomy, Non-surgical treatments; Procedure
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 501 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2015
U.S. locations: 13
States / cities: Oakland, California • San Francisco, California • Decatur, Georgia + 9 more

Conditions: Ankle Fracture
Interventions: Exparel; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 65 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions: Multimodal Analgesia, Patient controlled analgesia; Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: Not listed
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

VIA Disc NP Pilot for Patients With Symptomatic Degenerated Discs

ONC-MM-2407: The Effect of Virtual Reality Headsets on Pain and Anxiety in the Peri and Post Bone Marrow Biopsy Period

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib Fractures

Methylglyoxal Evaluation in Humans

Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery

Percutaneous Dynamic Stabilization (PDS) System Versus Fusion for Treating Degenerative Disc Disease

Distracting Through Procedural Pain and Distress

The Diagnostic Accuracy of the Clinical Examination

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma

Effectiveness of Cervical Transforaminal Epidural Steroid Injection

Non-surgical Spinal Decompression Therapy and Outcomes

Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis

A Prospective Study of Conventional Bone Marrow Biopsy Versus Portomar(TM) Biopsy

Sustained Acoustic Medicine for Chronic Low Back Pain Secondary to Herniated Nucleus Pulposus or Other Conditions

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

Regional Blocks for Lateral Condyle Fractures

Assessing the Potential for Improved Joint Health and Wellbeing by Providing a Whole Salmon Oil With Undenatured Type II Collagen Compared to Type II Collagen Alone

Low Dose Dexamethasone for Distal Radius Fractures

Focused Extracorporeal Shockwave Therapy for Knee Arthritis

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation

Exparel and Ankle Surgery

Multimodal Analgesia Versus Routine Care Pain Management