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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brachial Plexus Block Clear all
Completed Phase 4 Interventional

Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks

NCT05482113
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.25% Inj
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 4 Interventional

DBRCT on the Effect of Grip Strength in Brachial Plexus vs Distal Forearm Nerve Blocks

NCT01927289
View directory record Official record
Conditions
Postoperative Mobility
Interventions
Proximal Brachial Plexus vs Distal Forearm Block
Procedure
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 21, 2013 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Not applicable Interventional

Paravertebral Block With Brachial Plexus Block for Upper Arm Arteriovenous Fistula Surgery

NCT04720079
View directory record Official record
Conditions
Regional Anesthesia Success
Interventions
Subcutaneous infiltration of intercostobrachial nerve, T2 paravertebral nerve block
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function

NCT02059070
View directory record Official record
Conditions
Paresis
Interventions
Ropivacaine, Bupivacaine
Drug
Lead sponsor
Anesthesiology WSU/DMC-NorthStar
Other
Eligibility
18 Years to 70 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Madison Heights, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 24, 2014 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 3 Interventional Results available

Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery

NCT02713230
View directory record Official record
Conditions
Pain
Interventions
bupivacaine liposome injectable suspension, Placebo
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
17
States / cities
Mobile, Alabama • Englewood, Colorado • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jun 26, 2026, 3:02 PM EDT
Completed No phase listed Observational Results available

A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block

NCT02151487
View directory record Official record
Conditions
Upper Extremity Surgery
Interventions
Ropivacaine, Ropivacaine and dexamethasone, Ropivacaine and clonidine, Ropivacaine, dexamethasone and clonidine
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Jun 26, 2026, 3:02 PM EDT
Terminated Not applicable Interventional

Out of Plane Approach for Interscalene

NCT03785392
View directory record Official record
Conditions
Acute Pain, Brachial Plexus Block
Interventions
Group 1 In-plane, Group 2 out of plane
Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Galveston, Texas • League City, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Postoperative Pain Control in Total Shoulder Arthroplasty

NCT05068960
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Scripps Clinic
Other
Eligibility
50 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Not applicable Interventional Results available

Initial Local Anesthetic Dose With Continuous Interscalene Analgesia

NCT00672100
View directory record Official record
Conditions
Post-operative Pain
Interventions
Ropivacaine
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Royal Oak, Michigan • Troy, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 6, 2017 · Synced Jun 26, 2026, 3:02 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Inferior Vena Cava (IVC) Diameters Before & After Interscalene Block

NCT03989076
View directory record Official record
Conditions
IVC - Inferior Vena Cava Abnormality
Interventions
Interscalene Brachial Plexus Block
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Not applicable Interventional Results available

Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%

NCT01690663
View directory record Official record
Conditions
Post Surgical Pain
Interventions
Bupivacaine 0.25%, Dexamethasone, normal saline
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Jun 26, 2026, 3:02 PM EDT
Withdrawn Not applicable Interventional

Effectiveness of Ultrasound (US) Guided Supraclavicular Block

NCT00923494
View directory record Official record
Conditions
Analgesia, Pain
Interventions
20 ml of ropivacaine 0.5%, 30 ml of ropivacaine 0.5%, 40 ml of ropivacaine 0.5%
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Jun 26, 2026, 3:02 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks

NCT07099222
View directory record Official record
Conditions
Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation, Duration of Response, Narcotics Consumption, Pain After Surgery
Interventions
Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jun 26, 2026, 3:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Postoperative Analgesia After Shoulder Replacement

NCT01003860
View directory record Official record
Conditions
Analgesia
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 28, 2009 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 4 Interventional Results available

Dose-Response Relationships for Hemidiaphragmatic Paresis Following Ultrasound-Guided Supraclavicular Block

NCT03138577
View directory record Official record
Conditions
Surgery of Right Upper Extremity
Interventions
Ultrasound Imaging, Supraclavicular Block, Bedside Negative Inspiratory Force Meter
Diagnostic Test · Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 105 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Jun 26, 2026, 3:02 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants

NCT03845894
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine with adjuvants
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine vs Dexamethasone ISB

NCT04047446
View directory record Official record
Conditions
Shoulder Pain
Interventions
Exparel 133 MG Per 10 ML Injection, Dexamethasone
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Jun 26, 2026, 3:02 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

NCT05868993
View directory record Official record
Conditions
Post Operative Pain
Interventions
Dose of 0.5% Ropivacaine
Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Jun 26, 2026, 3:02 PM EDT
Withdrawn Not applicable Interventional

Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery

NCT02970097
View directory record Official record
Conditions
Wrist Injuries, Postoperative Pain Control
Interventions
20ml bolus of 0.5% ropivicaine, 10 ml of 0.5% ropivicaine, Midazolam, Fentanyl
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2020 · Synced Jun 26, 2026, 3:02 PM EDT
Withdrawn No phase listed Observational

The Effect of Brachial Plexus Nerve Block on Distal Peripheral Nerve Conduction

NCT01716078
View directory record Official record
Conditions
Anesthesia
Interventions
Not listed
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Fort Meade, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Jun 26, 2026, 3:02 PM EDT
Not listed No phase listed Observational

Phantom Limb Experience After Brachial Plexus Anesthesia

NCT03592901
View directory record Official record
Conditions
Phantom Limb, Brachial Plexus Block
Interventions
brachial plexus anesthesia
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced Jun 26, 2026, 3:02 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty

NCT02876055
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Jun 26, 2026, 3:02 PM EDT