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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Aneurysm Clear all
Recruiting Not applicable Interventional

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06377033
View directory record Official record
Conditions
Genetic Predisposition, Paraganglioma, Pheochromocytoma, ALS, Parkinson Disease, Polyneuropathies, Frontotemporal Dementia, Alzheimer Disease, Cardiomyopathy Non-ischemic, Thoracic Aortic Aneurysm
Interventions
Behavioral nudge
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Recruiting Not applicable Interventional

Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

NCT06693011
View directory record Official record
Conditions
Cerebral Aneurysms
Interventions
Contour Neurovascular System Treatment Attempt
Device
Lead sponsor
Cerus Endovascular, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
9
States / cities
Park Ridge, Illinois • Kansas City, Kansas • Buffalo, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Phase 3 Interventional

Hypothermia During Intracranial Aneurysm Surgery Trial

NCT00029133
View directory record Official record
Conditions
Aneurysm, Hypothermia, Subarachnoid Hemorrhage
Interventions
mild intraoperative hypothermia (33 degrees Celsius)
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
19 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Phase 1 Interventional

Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH

NCT02893826
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
EG-1962 (nimodipine microparticles), Enteral Nimodipine
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Phoenix, Arizona • San Francisco, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 24, 2026, 2:28 PM EDT
Recruiting No phase listed Observational

Stroke Thrombectomy and Aneurysm Registry

NCT04994756
View directory record Official record
Conditions
Stroke, Thromboses, Intracranial, Aneurysm, Brain
Interventions
Stroke/Thrombectomy/Aneurysm-specific surgical procedures
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Year to 120 Years
Enrollment
40,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2055
U.S. locations
54
States / cities
Birmingham, Alabama • Loma Linda, California • Santa Barbara, California + 48 more
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Researching AXIUM Coiling Experience and Recanalization (RACER)

NCT00703794
View directory record Official record
Conditions
Aneurysms, Vascular Diseases, Cerebrovascular Disorders, Intracranial Arterial Diseases
Interventions
The AXIUM Progressive Coil System
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
18
States / cities
Los Angeles, California • Orange, California • Fort Myers, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2018 · Synced Sep 24, 2026, 2:28 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices

NCT06215105
View directory record Official record
Conditions
Aneurysm Cerebral
Interventions
Intracranial Aneurysm Devices
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
Not listed
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
5
States / cities
Hollywood, Florida • Orlando, Florida • Iowa City, Iowa + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Active, not recruiting No phase listed Observational

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

NCT05155956
View directory record Official record
Conditions
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
Interventions
transcranial Doppler ultrasonography (TCD)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Early Phase 1 Interventional

Continuous Neurophysiological Monitoring Detection of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage Subjects

NCT01343537
View directory record Official record
Conditions
Cerebral Vasospasm, SAH, Aneurysm
Interventions
Neuro Monitoring
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 24, 2026, 2:28 PM EDT
Suspended Early Phase 1 Interventional Accepts healthy volunteers

Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation

NCT05153395
View directory record Official record
Conditions
Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction, Obesity
Interventions
Carbon dioxide breathing, Neurovascular Coupling, Human insulin
Other · Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Genetic Analysis of Familial Brain Aneurysms

NCT00011856
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Doppler Flow Wires in Cerebral Angiography

NCT03145701
View directory record Official record
Conditions
Aneurysm, Cerebral Aneurysm
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device

NCT01541254
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Albany, New York • Stony Brook, New York • Philadelphia, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Terminated Phase 4 Interventional Results available

Seizure Prophylaxis in Aneurysm Repair

NCT01974700
View directory record Official record
Conditions
Intracranial Aneurysms, Seizures
Interventions
Levetiracetam
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 10, 2016 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Genetic Analysis of PHACE Syndrome (Hemangioma With Other Congenital Anomalies)

NCT01016756
View directory record Official record
Conditions
PHACE Syndrome
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Not listed
Enrollment
341 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

NCT00962546
View directory record Official record
Conditions
Cerebral Vasospasm, Cerebral Aneurysm, Subarachnoid Hemorrhage
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Results available

Pivotal Study of the LVIS (Low Profile Visualized Intraluminal Support)

NCT01793792
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
LVIS™ and LVIS™ Jr
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
21
States / cities
Phoenix, Arizona • Carmichael, California • Englewood, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2025 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Results available

Reverse Medical Barrel™ Device for Adjunctive Treatment for Wide-Neck, Intracranial, Bifurcating/Branching Aneurysms

NCT02179190
View directory record Official record
Conditions
Intracranial Bifurcating Aneurysms
Interventions
BARREL VRD
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
18 Years to 85 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Jacksonville, Florida • Miami, Florida • Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Dec 25, 2018 · Synced Sep 24, 2026, 2:28 PM EDT
Completed Not applicable Interventional Results available

The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms

NCT01636453
View directory record Official record
Conditions
Wide-neck, Saccular Intracranial Aneurysms
Interventions
Stent assisted coiling with the Liberty Stent
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Denver, Colorado • Chicago, Illinois • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Sep 24, 2026, 2:28 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

NCT05526352
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Not listed
Lead sponsor
University Hospital, Geneva
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2040
U.S. locations
3
States / cities
San Francisco, California • Cincinnati, Ohio • Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Withdrawn Phase 2 Interventional

Targeted PET/CT and PET/MRI Imaging of Vascular Inflammation

NCT02995642
View directory record Official record
Conditions
Aortic Aneurysm, Abdominal, Carotid Atherosclerosis
Interventions
18F-FPPRGD2, Positron emission tomography, Computed tomography, Magnetic Resonance Imaging
Drug · Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Sep 24, 2026, 2:28 PM EDT
Completed No phase listed Observational

Beacon Tip Sizing Catheter and Slip-Cath Beacon Tip Catheter Study

NCT06986954
View directory record Official record
Conditions
Stenosis, Bleed Intracranial, Stroke, TIA, Vascular Malformation, Pseudoaneurysm
Interventions
Beacon Tip Catheters
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
Not listed
Enrollment
816 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Darien, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 24, 2026, 2:28 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage

NCT01878136
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Vasospasm, Cerebral Aneurysm, Hydrocephalus
Interventions
Tissue Plasminogen Activator
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2015 · Synced Sep 24, 2026, 2:28 PM EDT
Recruiting No phase listed Observational

Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry

NCT06282939
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
OPTIMA and OPTIMAX Coils manufactured by Balt USA
Device
Lead sponsor
HCA Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 24, 2026, 2:28 PM EDT