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ClinicalTrials.gov public records Last synced Sep 25, 2026, 5:32 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Aneurysms Clear all
Completed Not applicable Interventional Results available

Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil

NCT02729740
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Penumbra Smart Coil, Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
995 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
71
States / cities
Dothan, Alabama • Mesa, Arizona • Phoenix, Arizona + 62 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2021 · Synced Sep 25, 2026, 5:32 PM EDT
Active, not recruiting No phase listed Observational

Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

NCT05155956
View directory record Official record
Conditions
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Microemboli
Interventions
transcranial Doppler ultrasonography (TCD)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 25, 2026, 5:32 PM EDT
Withdrawn Phase 2 Interventional

Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH)

NCT02011321
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Aneurysm, Vasospasm, Intracranial
Interventions
clevidipine
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Sep 25, 2026, 5:32 PM EDT
Completed No phase listed Observational Results available

TransForm™ Occlusion Balloon Catheter Registry

NCT01949779
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
TransForm™ Occlusion Balloon Catheter
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years to 80 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Palm Springs, California • Lexington, Kentucky • Worcester, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 25, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Pipeline for Uncoilable or Failed Aneurysms

NCT00777088
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Pipeline Embolization Device (PED)
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
21 Years to 75 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
8
States / cities
Phoenix, Arizona • Chicago, Illinois • Winfield, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2018 · Synced Sep 25, 2026, 5:32 PM EDT
Terminated Early Phase 1 Interventional

Continuous Neurophysiological Monitoring Detection of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage Subjects

NCT01343537
View directory record Official record
Conditions
Cerebral Vasospasm, SAH, Aneurysm
Interventions
Neuro Monitoring
Other
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 89 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 25, 2026, 5:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Surgical Theater's Surgery Rehearsal Platform

NCT02099318
View directory record Official record
Conditions
Cerebral Aneurysm Unruptured, Cerebral Aneurysm Ruptured
Interventions
Active SRP cases, Control cases
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 25, 2026, 5:32 PM EDT
Withdrawn Not applicable Interventional

Remote Ischemic PreConditioning (RIPC)

NCT03814850
View directory record Official record
Conditions
Unruptured Cerebral Aneurysm
Interventions
Standard Manual Aneroid Sphygmomanometer
Device
Lead sponsor
Sebastian Koch
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 25, 2026, 5:32 PM EDT
Terminated Not applicable Interventional

EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)

NCT04391803
View directory record Official record
Conditions
Intracranial Aneurysm, Ruptured Aneurysm
Interventions
Pipeline™ Flex Embolization Device with Shield Technology™
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
7
States / cities
New Haven, Connecticut • Marietta, Georgia • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 25, 2026, 5:32 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced Sep 25, 2026, 5:32 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

NCT05526352
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Not listed
Lead sponsor
University Hospital, Geneva
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2040
U.S. locations
3
States / cities
San Francisco, California • Cincinnati, Ohio • Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 25, 2026, 5:32 PM EDT
Terminated No phase listed Observational

Genome-wide Analysis of Single Nucleotide Polymorphisms of Brain Arteriovenous Malformations and Cerebral Aneurysm

NCT01801488
View directory record Official record
Conditions
Arteriovenous Malformations, Intracranial Aneurysm, Subarachnoid Hemorrhage
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Sep 25, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Prospective Study on Embolization of Intracranial Aneurysms With Pipeline™ Embolization Device

NCT02186561
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Pipeline™ Embolization Device/ Pipeline™Flex Embolization Device
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 80 Years
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
22
States / cities
Englewood, Colorado • Jacksonville, Florida • Tampa, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Sep 25, 2026, 5:32 PM EDT
Not listed No phase listed Observational

TARGET Intracranial Aneurysm Coiling Registry

NCT01748903
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Target 360°, 2D Coils, Nano Coils
Device
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
9
States / cities
Phoenix, Arizona • Tallahassee, Florida • Joliet, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 25, 2026, 5:32 PM EDT
Terminated Phase 1 Interventional

Safety/Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With aSAH

NCT02893826
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
EG-1962 (nimodipine microparticles), Enteral Nimodipine
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Phoenix, Arizona • San Francisco, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 25, 2026, 5:32 PM EDT
Not listed Not applicable Interventional

Barrow Ruptured Aneurysm Trial

NCT01593267
View directory record Official record
Conditions
Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH)
Interventions
coil embolization, clip occlusion
Procedure
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 25, 2026, 5:32 PM EDT
Terminated Phase 3 Interventional

Study of EG-1962 Compared to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage

NCT02790632
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
EG-1962 (nimodipine microparticles), Enteral Nimodipine
Drug
Lead sponsor
Edge Therapeutics Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
45
States / cities
Birmingham, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 25, 2026, 5:32 PM EDT
Not listed Not applicable Interventional

Prospective Packing Density With Target Coils I

NCT02292017
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Embolization of intracranial aneurysm
Device
Lead sponsor
Tennessee Neurovascular Institute, LLC
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 25, 2026, 5:32 PM EDT
Completed Not applicable Interventional Results available

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

NCT02701582
View directory record Official record
Conditions
Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
Interventions
Phenylephrine, Epinephrine, Albumin, Voluven, Normal Saline, Packed Red Blood Cells, FloTrac Monitor
Drug · Other · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
15 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 25, 2026, 5:32 PM EDT
Completed No phase listed Observational

Platelet Activity in Vascular Surgery for Thrombosis and Bleeding

NCT01897103
View directory record Official record
Conditions
Peripheral Vascular Disease, Peripheral Artery Disease, Carotid Stenosis, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Amputation, Wound, Embolism and Thrombosis, Aortic Aneurysm
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Sep 25, 2026, 5:32 PM EDT
Completed No phase listed Observational Results available

Success in Comaneci-assist Coils Embolization Surveillance Study (SUCCESS)

NCT04518670
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Comaneci Embolization Assist Device
Device
Lead sponsor
Rapid Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Mobile, Alabama • Tucson, Arizona • Santa Barbara, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 25, 2026, 5:32 PM EDT
Completed No phase listed Observational

Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study

NCT02684500
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Ultrasound
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 25, 2026, 5:32 PM EDT
Active, not recruiting Not applicable Interventional

A Medical Device to Treat Wide-Neck Brain Aneurysms

NCT05550571
View directory record Official record
Conditions
Ruptured Cerebral Aneurysm
Interventions
Nautilus Intrasaccular Bridging System
Device
Lead sponsor
EndoStream Medical
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Jacksonville, Florida • Tampa, Florida • Buffalo, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 25, 2026, 5:32 PM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial

NCT01895881
View directory record Official record
Conditions
Cerebral Aneurysm, Menopause, Treatment
Interventions
Estradiol, Placebo
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
40 Years to 52 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 25, 2026, 5:32 PM EDT