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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:03 AM EDT

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Showing 1–24 of 119 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Brain Connectivity Clear all
Withdrawn Phase 4 Interventional

Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes

NCT03580967
View directory record Official record
Conditions
Type2 Diabetes, Major Depressive Disorder
Interventions
Vortioxetine
Drug
Lead sponsor
Todd Doyle
Other
Eligibility
40 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Brain Connectivity in Depression

NCT03276793
View directory record Official record
Conditions
Depression
Interventions
MRI scan, Behavioral testing
Other · Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 21, 2025 · Synced Oct 22, 2026, 3:03 AM EDT
Completed Not applicable Interventional Results available

PharmacoMRI of Parkinson Disease

NCT01528592
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Carbidopa-Levodopa
Drug
Lead sponsor
Northwestern University
Other
Eligibility
30 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Use of Circadian Reset Technology to Alter REM Sleep and Appetitive Control in Patients With Binge Eating Disorder

NCT06858774
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Circadian Reset Technology, VR Headset
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Effects of Transcranial Magnetic Stimulation on Social Cognition, Cognitive Processing, and Functional Brain Architecture

NCT07635940
View directory record Official record
Conditions
Psychopathy
Interventions
continuous theta burst stimulation (cTBS), Intermittent theta burst stimulation (iTBS), Sham
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Resting State Changes Following Theta Burst Stimulation

NCT05322239
View directory record Official record
Conditions
Brain Connectivity
Interventions
Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation
Device
Lead sponsor
Nicholas Balderston, PhD
Other
Eligibility
18 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Glutamate, Brain Connectivity and Duration of Untreated Psychosis

NCT02034253
View directory record Official record
Conditions
Schizophrenia, Psychosis, Schizoaffective Disorder
Interventions
Risperidone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
17 Years to 35 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 22, 2019 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)

NCT00964236
View directory record Official record
Conditions
Phenylketonuria
Interventions
Sapropterin
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
6 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 4, 2018 · Synced Oct 22, 2026, 3:03 AM EDT
Withdrawn Not applicable Interventional

Functional Connectivity and Predictors of Affective Aprosodia Intervention in Subacute Right Hemisphere Stroke

NCT04575909
View directory record Official record
Conditions
Right Hemispheric Stroke
Interventions
Aprosodia Intervention, No-Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Activity in Visual-Motor Behavior

NCT00077038
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
20 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Connections for Arm Movement After Stroke

NCT04286516
View directory record Official record
Conditions
Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 90 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining Bladder Control Using Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI)

NCT01110278
View directory record Official record
Conditions
Urinary Incontinence, Urge
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 85 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Cognitive and Emotional Health From Neurocircuitry Following TBI

NCT01803048
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
20 Years to 45 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 22, 2026, 3:03 AM EDT
Not listed No phase listed Observational

Advanced MRI In Acute Military TBI

NCT01313130
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)

NCT06961916
View directory record Official record
Conditions
Schizophrenia
Interventions
Active rTMS, Cognitive Training
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Successful Deep Brain Stimulation to the Dentato-rubro-thalamic Tract

NCT04758624
View directory record Official record
Conditions
Essential Tremor
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Not applicable Interventional

Personalized Transcranial Direct Current Stimulation in Stroke Recovery

NCT06286800
View directory record Official record
Conditions
Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
Interventions
Transcranial direct current stimulation (tDCS) with OT, Sham tDCS with OT
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Neuroimaging of Parkinson's

NCT07024875
View directory record Official record
Conditions
Parkinsons Disease (PD)
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Recruiting Phase 2 Interventional

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

NCT06376734
View directory record Official record
Conditions
Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Sunnyvale, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 22, 2026, 3:03 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Role of Mid-Life Adiposity in Functional Brain Connectivity

NCT01777789
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Oct 22, 2026, 3:03 AM EDT
Completed No phase listed Observational

Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment

NCT01364818
View directory record Official record
Conditions
Autism Spectrum Disorders, Psychosis, Fragile X Syndrome
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
3 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Oct 22, 2026, 3:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Functional Connectivity In Relation To Proprioception and Sensorimotor Recovery in Stroke Patients (Feasibility Study)

NCT02445768
View directory record Official record
Conditions
Stroke
Interventions
Cognitive multisensory rehabilitation
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Oct 22, 2026, 3:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Effects on Brain Health and Learning From Minutes to Months

NCT03114150
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Cardiorespiratory fitness training, Functional fitness training
Behavioral
Lead sponsor
Michelle W. Voss
Other
Eligibility
55 Years to 80 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 22, 2026, 3:03 AM EDT
Not listed Not applicable Interventional

Stroke Recovery and Music or No Music

NCT03608904
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Music listening, Spoken word (language) listening
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 22, 2026, 3:03 AM EDT