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ClinicalTrials.gov public records Last synced Oct 20, 2026, 9:06 AM EDT

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Showing 1–24 of 2,205 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Brain Injuries Clear all
Completed Phase 1 Interventional

Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression

NCT00961454
View directory record Official record
Conditions
Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
Interventions
Photobiomodulation with a super-luminous light emitting diode
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2009 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex and Age Ultrasound Response to Differential Jugular Vein Pressure

NCT03017937
View directory record Official record
Conditions
Concussion, Mild
Interventions
Q-collar
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 60 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 20, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Psychological and Vestibular Health: MINDGAPS

NCT05986279
View directory record Official record
Conditions
Vestibular Hypofunction
Interventions
Rehab
Other
Lead sponsor
University of Montana
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Diego, California • Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 20, 2026, 9:06 AM EDT
Terminated Phase 3 Interventional

Hypothermia in Children After Trauma

NCT00222742
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
induced moderate hypothermia
Procedure
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
17
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 11, 2012 · Synced Oct 20, 2026, 9:06 AM EDT
Terminated Phase 4 Interventional Results available

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

NCT06081283
View directory record Official record
Conditions
Brain Injuries, Acute, Brain Injuries, Traumatic, Brain Ischemia, Brain Hypoxia, Hypoxia-Ischemia, Brain, Heart Arrest, Stroke, Intracranial Hemorrhages, Coma, Persistent Vegetative State
Interventions
Phenobarbital Sodium Injection, Levetiracetam, Lacosamide Injectable Product, Valproate Sodium, Fosphenytoin
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Months to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2025 · Synced Oct 20, 2026, 9:06 AM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Heart Rate Variability Biofeedback Following Traumatic Brain Injury

NCT05913505
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
OSC-
Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mindfulness Based Stress Reduction on Patients With Traumatic Brain Injury

NCT01613872
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injury, Stress
Interventions
Mindfulness Based Stress Reduction
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
30 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Oct 20, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional

Motor Training for Infants With Cerebral Palsy

NCT04886895
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Let's Move Motor Intervention
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Months to 8 Months
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 20, 2026, 9:06 AM EDT
Terminated Not applicable Interventional Results available

Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children

NCT00955877
View directory record Official record
Conditions
Spastic Cerebral Palsy
Interventions
Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 12 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Assistive Hip Exoskeleton Study for Stroke

NCT03924765
View directory record Official record
Conditions
Lower Limb Injury, Stroke
Interventions
Powered hip exoskeleton
Device
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 20, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury

NCT04242602
View directory record Official record
Conditions
Traumatic Brain Injury, Brain Injuries, Brain Injury, Vascular
Interventions
Transcranial Doppler
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
28 Days to 18 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Brain Stimulation and Injury Risk Biomechanics

NCT06093295
View directory record Official record
Conditions
Concussion, Mild
Interventions
Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation)
Device
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 20, 2026, 9:06 AM EDT
Completed No phase listed Observational

Definition, Quantification, and Utility of Biomarkers of Repetitive Brain Injury in Predicting Concussion and Other Long-Term Injury Risks in Patients With Atrial Fibrillation (Concussion AF)

NCT03875131
View directory record Official record
Conditions
Cognitive Change
Interventions
Biomarkers of Dementia and Cognitive Decline
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
65 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 24, 2024 · Synced Oct 20, 2026, 9:06 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity Mobility

NCT07873151
View directory record Official record
Conditions
Spinal Cord Injury (=3 Years), Traumatic Brain Injury (TBI) Patients, Healthy Adult Participants
Interventions
voice-activated call light
Device
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Not listed Not applicable Interventional

Transcutaneous Pulse Oximetry Brain Monitoring Study (US)

NCT06267131
View directory record Official record
Conditions
Acute Brain Injury
Interventions
Brain Pulse Oximeter
Device
Lead sponsor
Cyban Pty Ltd
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Impact of Custom Assistive and Adaptive Technology in Rehabilitation

NCT03567239
View directory record Official record
Conditions
Disability Physical, Brain Injuries, Stroke, Spinal Cord Injuries, Multiple Sclerosis, Paralysis
Interventions
Using adaptive device.
Device
Lead sponsor
Madonna Rehabilitation Hospital
Other
Eligibility
1 Year to 85 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 20, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

NCT07357428
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis, Cervical Spinal Cord Injury, Dysarthria
Interventions
Connexus Brain-Computer Interface
Device
Lead sponsor
Paradromics
Industry
Eligibility
22 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
3
States / cities
Sacramento, California • Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Community-based Implementation of Online EmReg

NCT05933629
View directory record Official record
Conditions
Traumatic Brain Injury, Emotion Regulation
Interventions
Online EmReg, Consultation Sessions
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Study to Identify Biomarkers Associated With Chronic Traumatic Brain Injury

NCT01171131
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Blood/saliva sampling
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study

NCT07567053
View directory record Official record
Conditions
Cerebral Palsy, Typically Developing Children
Interventions
MRI, HD-EEG Recording, rTMS
Device
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
6 Years to 20 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 20, 2026, 9:06 AM EDT
Withdrawn Not applicable Interventional

Mag Con: Efficacy of Oral Mag. in Acute Concussion in Adolescents

NCT05065528
View directory record Official record
Conditions
Concussion, Mild, Traumatic Brain Injury, Mild
Interventions
Magnesium, Placebo
Dietary Supplement · Drug
Lead sponsor
Corewell Health South
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Youth Soccer Header Study

NCT04919707
View directory record Official record
Conditions
Brain Injuries
Interventions
Header Session, MRI Session
Behavioral · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Years to 18 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Oct 20, 2026, 9:06 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Traumatic Brain Injury and Yoga

NCT03008434
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Assigned Interventions
Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Oct 20, 2026, 9:06 AM EDT
Not yet recruiting Not applicable Interventional

SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.

NCT06882239
View directory record Official record
Conditions
Persistent Post-concussive Symptoms, Post Traumatic Headache
Interventions
SPINEPASS Physical Therapy, Standard Physical Therapy
Other
Lead sponsor
The University of Queensland
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 20, 2026, 9:06 AM EDT