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Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Interventions: Intravenous and Intranasal BMSC; Procedure
Lead sponsor: MD Stem Cells; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2028
U.S. locations: 2
States / cities: Westport, Connecticut • Coral Springs, Florida

Conditions: Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Infantile, Infant
Interventions: Caregiver knowledge, Physical therapy, Occupational Therapy; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 3 Months to 15 Months
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Oakland, California

Conditions: Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis), Muscle Spasticity, Cerebral Palsy, Spastic
Interventions: Prometra II Programmable Pump - Flowonix Medical; Device
Lead sponsor: Culicchia Neurological Clinic; Other
Eligibility: 22 Years to 85 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Marrero, Louisiana

Conditions: Mental Retardation, Developmental Disabilities, Intellectual Disabilities
Interventions: Healthy Lifestyles Curriculum; Behavioral
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Cerebral Palsy, Spasticity
Interventions: IncobotulinumtoxinA (8 Units per kg body weight), IncobotulinumtoxinA (6 Units per kg body weight), IncobotulinumtoxinA (2 Units per kg body weight); Drug
Lead sponsor: Merz Pharmaceuticals GmbH; Industry
Eligibility: 2 Years to 17 Years
Enrollment: 351 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 6
States / cities: Gulf Breeze, Florida • Loxahatchee Groves, Florida • Savannah, Georgia + 3 more

Conditions: Chronic Subdural Hematoma
Interventions: Experimental: Interventional Cohort: TRUFILL n-Butyl Cyanoacrylate (n-BCA) Liquid Embolic System, Standard of Care Surgery, Experimental: Interventional Cohort: TRUFILL n-BCA Liquid Embolic System, Standard of Care Medical Management; Device · Other
Lead sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 376 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 31
States / cities: Birmingham, Alabama • Tucson, Arizona • Walnut Creek, California + 28 more

Conditions: Chronic Subdural Hematoma
Interventions: embolization therapy Bilateral, embolization therapy Unilateral; Device
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Brain Injuries, Brain Injuries, Traumatic, Injury, Brain, Traumatic, Traumatic Brain Injury, Brain Injury, Chronic
Interventions: CLSI, MI, CR, CLSI - Unknown; Behavioral
Lead sponsor: Center for Vision Development, New Market, Maryland; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: New Market, Maryland

Conditions: Dystonic Cerebral Palsy
Interventions: Titration protocol; Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 17 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cerebral Palsy
Interventions: Not listed
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 16 Years to 89 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cerebral Palsy Spastic Diplegia
Interventions: FES, Cycling; Device · Other
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 10 Years to 18 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cerebral Palsy, Developmental Delay, Stroke, Fine Motor Delay, Infant Development, Other Development Delays
Interventions: SmarToyGym; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 3 Months to 11 Months
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Cerebral Palsy
Interventions: Robotic Ankle Assist Device (RAAD); Device
Lead sponsor: BiOMOTUM, Inc.; Industry
Eligibility: 8 Years to 21 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Flagstaff, Arizona

Conditions: Dystonia, Epilepsy in Children, Cerebral Palsy, Tourette Syndrome, Obsessive-Compulsive Disorder, Neurologic Disorder, Movement Disorders in Children, Movement Disorders, Deep Brain Stimulation
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 0 Years to 18 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Traumatic Brain Injury
Interventions: Autologous cord blood; Biological
Lead sponsor: Charles Cox; Other
Eligibility: 18 Months to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Cerebral Palsy, Hemiplegic
Interventions: tDCS, CIMT, sham tDCS; Device · Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 5 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cerebral Palsy
Interventions: Lokomat (LOK), Gait focused physical therapy (fPT), LOK + fPT; Procedure
Lead sponsor: University of Alberta; Other
Eligibility: 5 Years to 18 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Spinal Cord Injury
Interventions: Transcranial direct current stimulation; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Infant Development, Perinatal Stroke, Hemiparesis, Cerebral Palsy
Interventions: Non interventional study; Other
Lead sponsor: Ohio State University; Other
Eligibility: 4 Months to 36 Months
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Chronic Subdural Hematoma
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 15
States / cities: Coral Gables, Florida • Jacksonville, Florida • Orlando, Florida + 10 more

Conditions: Cerebral Palsy
Interventions: Gait Therapy; Behavioral
Lead sponsor: Father Flanagan's Boys' Home; Other
Eligibility: 13 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Boys Town, Nebraska

Conditions: Brain Injury, Sequelae, Stroke, Anoxia, Trauma
Interventions: Hyperbaric oxygen therapy (HBO2); Procedure
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 80 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2010
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: CTE, TBI (Traumatic Brain Injury)
Interventions: [F-18]FDDNP; Radiation
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 90 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cerebral Palsy (CP), Stroke, Spinal Cord Injury, Traumatic Brain Injury, Charcot Marie Tooth Disease (CMT), Spina Bifida
Interventions: Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6.; Behavioral
Lead sponsor: University of Hartford; Other
Eligibility: 8 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: West Hartford, Connecticut

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Neurologic Stem Cell Treatment Study

Coaching, Learning, Empowerment in Cerebral Palsy - a 6-Week Integrated PT/OT Caregiver "Primer" Bootcamp for Infants Diagnosed With or at High Risk for Cerebral Palsy

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

Healthy Lifestyles for People With Intellectual Disabilities

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral Palsy

Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL® n-BCA

Assessing Outcomes of Coil Embolization for Unilateral vs Bilateral Chronic Subdural Hematomas

How Well do Patients With Traumatic Brain Injury Learn New Material Using Learning Styles in Online Science Classrooms?

Intrathecal Baclofen and Pediatric Dystonia

Diet and Activity in Cerebral Palsy

FES Assisted Cycling in Children With CP

SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants

Development of a Robotic Ankle Assist Device

A Multicenter Pediatric Deep Brain Stimulation Registry

Safety Study of Umbilical Cord Blood To Treat Pediatric Traumatic Brain Injury

Cerebral pAlsy Motor Promotion With Transcranial Direct Current Stimulation (CAMP-tDCS)

Effectiveness of Robotic Gait Training and Physical Therapy for Children and Youth With Cerebral Palsy

Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury

Behavioral Assessment Method Index

Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

Igniting Mobility in Adolescents and Young Adults With Cerebral Palsy

Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury

Traumatic Brain Injury and Risk for Chronic Traumatic Encephalopathy

High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction