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Showing 1–24 of 555 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Brain Injury, Chronic Clear all
Not listed Not applicable Interventional

TeleRehab to Restore Upper Limb Function in People With Chronic TBI

NCT06184932
View directory record Official record
Conditions
Traumatic Brain Injury, Upper Extremity Dysfunction, Disability Physical
Interventions
HAHE, Exergame
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
45 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

Retention of Whole-body Training Effects on Ambulatory Function in Children With Cerebral Palsy

NCT04961749
View directory record Official record
Conditions
CP, Gait Disorders, Neurologic, Locomotion Disorder, Neurologic
Interventions
Whole body vibration training
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
8 Years to 12 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Terminated Phase 3 Interventional Results available

Treatment of Chronic Post-Traumatic Headache With OnabotulinumtoxinA

NCT02160535
View directory record Official record
Conditions
Chronic Post Traumatic Headache
Interventions
OnabotulinumtoxinA
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

NCT06070233
View directory record Official record
Conditions
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
Interventions
stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation, Sham
Radiation · Other
Lead sponsor
Ohio State University
Other
Eligibility
16 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Winter Park, Florida • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

Transcranial Direct-Current Stimulation (tCDS) and Robotics for Children With Hemiplegia

NCT03145532
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegia
Interventions
tDCS plus robotic training
Other
Lead sponsor
Blythedale Children's Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial

NCT06075797
View directory record Official record
Conditions
Cerebral Palsy Infantile, Disabilities Multiple, Pain
Interventions
PediQUEST ResPOND
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
1 Year and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Birmingham, Alabama • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 1 Interventional

Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study

NCT01253083
View directory record Official record
Conditions
Developmental Delay, Cerebral Palsy
Interventions
mobility training with dynamic body weight support
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
12 Months to 36 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

NCT02266329
View directory record Official record
Conditions
Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional

The Feasibility of Telehealth HEP for CP (HEP: Home Exercise Program), (CP: Cerebral Palsy)

NCT04423653
View directory record Official record
Conditions
Cerebral Palsy, Spastic, Telemedicine
Interventions
Telehealth home exercise program
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
11 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jul 21, 2026, 6:07 PM EDT
Terminated Phase 2 Interventional

Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

NCT02148783
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
methylphenidate, Placebo
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 2 Interventional Results available

A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children With Cerebral Palsy

NCT01147653
View directory record Official record
Conditions
Cerebral Palsy, CP, Spastic Cerebral Palsy
Interventions
Autologous UCB Reinfusion, Placebo
Biological · Other
Lead sponsor
Joanne Kurtzberg, MD
Other
Eligibility
12 Months to 6 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Using Augmented Reality to Promote Physical Activity in Children With Cerebral Palsy

NCT06096272
View directory record Official record
Conditions
Cerebral Palsy, Mobile Phone Use, Pediatric ALL, Physical Disability, Physical Inactivity
Interventions
Augment Reality Exergames
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
5 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational

Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers

NCT01971957
View directory record Official record
Conditions
Sjogren-Larsson Syndrome (SLS)
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
2
States / cities
Omaha, Nebraska • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

NCT06036199
View directory record Official record
Conditions
Cerebral Palsy, Dyskinetic, Secondary Dystonia
Interventions
Focused Ultrasound Pallidotomy
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
8 Years to 22 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health

NCT04641832
View directory record Official record
Conditions
Concussion, Mild
Interventions
Soccer heading
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 26 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional

NDT Effectiveness Study

NCT05070910
View directory record Official record
Conditions
Cerebral Palsy, Neuromuscular Diseases, Neurodevelopment Treatment
Interventions
Therapy
Behavioral
Lead sponsor
MultiCare Health System Research Institute
Other
Eligibility
2 Years to 15 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Puyallup, Washington
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational

Intensive Activities-based Locomotor Training Program in Children With Cerebral Palsy

NCT05867628
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Activities-based locomotor training (physical therapy)
Other
Lead sponsor
Baylor University
Other
Eligibility
2 Years to 12 Years
Enrollment
7 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Not applicable Interventional Results available

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)

NCT04283994
View directory record Official record
Conditions
Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions
Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Jul 21, 2026, 6:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

HMB Cerebral Palsy Pilot Study

NCT05384951
View directory record Official record
Conditions
Cerebral Palsy
Interventions
HMB + Vitamin D3
Dietary Supplement
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
13 Years to 17 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jul 21, 2026, 6:07 PM EDT
Completed Phase 2 Interventional Results available

Tau Imaging of Chronic Traumatic Encephalopathy

NCT02191267
View directory record Official record
Conditions
Chronic Traumatic Encephalopathy
Interventions
[F18]-T807, [F18]-Florbetapir, MRI/MRS, Genetic Analysis for Genetic Risk Score for Tau.
Radiation · Device · Genetic
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 69 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Neurologic Stem Cell Treatment Study

NCT02795052
View directory record Official record
Conditions
Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Interventions
Intravenous and Intranasal BMSC
Procedure
Lead sponsor
MD Stem Cells
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
2
States / cities
Westport, Connecticut • Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational

Diet and Activity in Cerebral Palsy

NCT02175108
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
16 Years to 89 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Jul 21, 2026, 6:07 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Eye-Hand Coordination in Children With Spastic Diplegia

NCT00024791
View directory record Official record
Conditions
Diplegia, Spastic
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 21, 2026, 6:07 PM EDT
Recruiting Not applicable Interventional

Implementation of Therapy Together

NCT06040619
View directory record Official record
Conditions
Cerebral Palsy, Hemiplegic Cerebral Palsy
Interventions
Therapy Together, Usual Care
Behavioral
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
3 Months to 71 Months
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jul 21, 2026, 6:07 PM EDT