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ClinicalTrials.gov public records Last synced Nov 5, 2026, 12:15 PM EST

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Showing 457–480 of 1,431 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Brain Stimulation Clear all

Conditions: Unipolar Depression
Interventions: MRI, MagPro TMS stimulator and coil, Thymatron (R) System IV paired with 4X1 HDECT; Device
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 22 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Epilepsy, Seizure Disorders
Interventions: Trigeminal Nerve Stimulation; Device
Lead sponsor: Olive View-UCLA Education & Research Institute; Other
Eligibility: 18 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 2
States / cities: Los Angeles, California • Sylmar, California

Conditions: Functional Gastrointestinal Disorders, Hypermobile Ehlers-Danlos Syndrome, Postural Orthostatic Tachycardia Syndrome, Autonomic Nervous System Disease, Autonomic Nervous System Imbalance
Interventions: Percutaneous vagal nerve stimulation (pVNS) device, Acoustic vagal nerve stimulation (aVNS) treatment; Device · Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 10 Years to 18 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions: Non-invasive pairing of cortical and spinal stimulation, Intraoperative pairing of cortical and spinal stimulation, Non-invasive repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP), Intraoperative repeated pairing of cortical and spinal stimulation (SCAP) at or below myelopathic region; Procedure
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 3
States / cities: New York, New York

Conditions: Stroke, Stroke, Ischemic, Stroke Hemorrhagic
Interventions: Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Bipolar Depression
Interventions: Medtronic Percept RC System, One Month Blinded Discontinuation Period; Device · Behavioral
Lead sponsor: Wayne Goodman MD; Other
Eligibility: 22 Years to 64 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 4
States / cities: Boston, Massachusetts • Houston, Texas • Seattle, Washington

Conditions: Fibromyalgia (FM)
Interventions: rTMS; Other
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Visuomotor Skills, Brain Lesion (General)
Interventions: repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Epilepsy, Brain Injury
Interventions: Low-level cortical stimulation; Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2023
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alzheimer Disease
Interventions: Intermittent theta burst stimulation active coil, Sham coil; Device
Lead sponsor: HealthPartners Institute; Other
Eligibility: 40 Years to 90 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Parkinson's Disease With Deep Brain Stimulation
Interventions: Not listed
Lead sponsor: Great Lakes NeuroTechnologies Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 2
States / cities: Cincinnati, Ohio • Cleveland, Ohio

Conditions: Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
Interventions: Medtronic Summit RC+S or Percept RC; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 22 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2030
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Parkinson Disease, Dystonia
Interventions: Summit RC+S for Motor, 8-week pilot trial of Closed-loop vs. Open-loop Stimulation, Summit RC+S for Sleep; Device · Diagnostic Test
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Opioid-use Disorder
Interventions: Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: Rutgers University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Aphasia
Interventions: rTMS, tDCS, Sham rTMS, Sham tDCS; Device
Lead sponsor: Dr. Alexander Thiel; Individual
Eligibility: 50 Years to 85 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Stroke, Cerebrovascular Disorders, Nervous System Diseases, Brain Diseases, Cardiovascular Diseases, Vascular Diseases, Central Nervous System Diseases
Interventions: rTMS Contralesional M1, rTMS Contralesional PMC, rTMS Ipsilesional PMC, rTMS sham at Ipsilesional M1; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 21 Years and older
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Major Depressive Disorder
Interventions: Neuroimaging with Magnetic Resonance Imaging (MRI); Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Epilepsy, Partial Seizure, Neurostimulator; Complications, Drug Resistant Epilepsy, Focal Epilepsy
Interventions: RNS System; Device
Lead sponsor: NeuroPace; Industry
Eligibility: 12 Years to 17 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: Grand Rapids, Michigan • Hawthorne, New York

Conditions: Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
Interventions: Sham, Low dose tDCS, High dose tDCS, mCIMT; Device · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 14
States / cities: Birmingham, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 11 more

Conditions: Spinal Cord Injuries
Interventions: Brain-Computer Interface-Triggered Transcutaneous Spinal Cord Stimulation (BCI-tSCS) System; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 70 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Cushing's Disease, Pituitary Adenoma
Interventions: Desmopressin acetate; Drug
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 8 Years to 99 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Mild Cognitive Impairment (MCI), Mild Neurocognitive Disorder, Neurocognitive Disorders, Cognitive Dysfunction, Cognition Disorders
Interventions: Accelerated iTBS, Computerized Cognitive Training, Sham Computerized Cognitive Training; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 60 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Mild Cognitive Impairment, Alzheimer Dementia (AD)
Interventions: Closed-loop TBS, Open-loop TBS; Device
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 90 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Parkinson Disease
Interventions: transcranial direct current stimulation, Sham (for transcranial direct current stimulation); Device
Lead sponsor: Sanford Health; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Fargo, North Dakota

Search by objective public record fields.

Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

External Trigeminal Nerve Stimulation for Epilepsy

Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome

Spinal Cord Associative Plasticity Study

At-Home taVNS - Stroke Rehab

Deep Brain Stimulation of Treatment-Resistant Bipolar Depression

Investigating the Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on the Brain in People With Fibromyalgia

Closed-loop rTMS-EEG During Visuomotor Integration.

Optimization of Human Cortical Stimulation

TMS Pilot in Early AD II

Parkinstep: Automated PD Gait and Balance Assessment for Optimizing DBS

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery

Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity

Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation Therapy

RNS System RESPONSE Study

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

Brain-Controlled Spinal Stimulation Walking Therapy After Incomplete Spinal Cord Injury (SCI)

DDAVP for Pituitary Adenoma

Brain Stimulation and Cognitive Training for MCI

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients