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Showing 529–552 of 1,432 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive VNS to Facilitate Excitability in Motor Cortex

NCT04130646
Conditions
Stroke, Stroke Sequelae, Motor Activity
Interventions
Transcranial Magnetic Stimulation, transcutaneous auricular vagus nerve stimulation (taVNS)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Spinal Cord Injury/Disorder, Stroke, Multiple Sclerosis, Traumatic Brain Injury
Interventions
Exercise with Electrical Stimulation
Other
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2031
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Partial Epilepsy, Seizures
Interventions
Cadwell High-Speed Magnetoelectric Stimulator, Magpro High-Speed Magnetoelectric Stimulator
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Parkinson Disease
Interventions
Anodal tDCS, SHAM tDCS
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
60 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
Post Traumatic Stress Disorder
Interventions
Transcranial Direct Current Stimulator, Written Exposure Therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Movement Disorders, Parkinson Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Not yet recruiting Phase 1Phase 2 Interventional

Brain State-dependent PCMS in Chronic Stroke

NCT04830163
Conditions
Stroke
Interventions
Brain state-dependent paired corticomotoneuronal stimulation (PCMS)
Combination Product
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Austin, Texas
Conditions
Consciousness Disorders, Brain Injury, Altered Level of Consciousness
Interventions
Transcutaneous vagus nerve stimulation (taVNS), Physical therapy using Hocoma, Standard of Care
Device · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Major Depressive Episode, Depression - Major Depressive Disorder, Treatment-Resistant Major Depressive Disorder
Interventions
LTFUS to SCC, LTFUS to ALIC
Device
Lead sponsor
Brian Mickey
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Terminated Not applicable Interventional Accepts healthy volunteers Results available

H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil

NCT04203199
Conditions
Healthy, Chronic Pain, Opioid Use, Pain, Chronic
Interventions
Real rTMS to the mPFC using H7 Coil, Real rTMS to the dlPFC using H1 Coil
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Stroke, Aphasia, Aphasia Following Cerebral Infarction
Interventions
Transcranial Magnetic Stimulation (TMS), Modified Constraint Induced Language Therapy (mCILT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Patients With Drug-resistant Focal Epilepsy, SEEG as Part of Presurgical Evaluation
Interventions
Direct Electric Stimulation (DES)
Other
Lead sponsor
Hospices Civils de Lyon
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Modulation of Brain Oscillations Underlying Working Memory

NCT05923606
Conditions
Working Memory
Interventions
Active tACS, Placebo tACS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Epilepsy
Interventions
HD Transcranial Direct Stimulation
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
9 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Conditions
Stroke
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Parkinson's Disease, Deep Brain Stimulation
Interventions
Exercise
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cervicogenic Headache, Occipital Neuralgia
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
10
States / cities
Santa Rosa, California • Waltham, Massachusetts • Rochester, Minnesota + 7 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Noninvasive Brain Stimulation in Adult Amblyopia

NCT06712849
Conditions
Amblyopia
Interventions
Sham Transcranial Random Noise Stimulation, High Frequency Transcranial Random Noise Stimulation
Device
Lead sponsor
Midwestern University
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Downers Grove, Illinois
Conditions
Obsessive-Compulsive Disorder
Interventions
Active DBS, Sham DBS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2024
U.S. locations
9
States / cities
Redwood City, California • Washington D.C., District of Columbia • Gainesville, Florida + 6 more
Conditions
Stroke, Chronic Stroke Patients, Arm Weakness as a Consequence of Stroke
Interventions
kTMP, Sham kTMP
Device
Lead sponsor
Magnetic Tides
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Conditions
Large Vessel Occlusion, Acute Ischemic Stroke
Interventions
transcutaneous auricular vagal nerve stimulation, Sham transcutaneous vagal nerve stimulation
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

DBS Recordings to Characterize Movement Facilitation in Parkinson's Disease

NCT05166655
Conditions
Parkinson Disease
Interventions
Movement task
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Stroke
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Enspire DBS Therapy, Inc.
Industry
Eligibility
25 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio