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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:07 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 1,432 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Brain Stimulation Clear all

Conditions: Dystonia
Interventions: implanted pulse generator; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2000
U.S. locations: 1
States / cities: New York, New York

Conditions: Alzheimer's Disease
Interventions: Deep Brain Stimulation; Device
Lead sponsor: Ali Rezai, MD; Other
Eligibility: 45 Years to 85 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Aging, Postural Balance, Motor Adaptation
Interventions: Transcranial Magnetic Stimulation Assessment, Reactive Balance Adaptation Task; Device · Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 95 Years
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Logopenic Variant Primary Progressive Aphasia, Non-Fluent Primary Progressive Aphasia
Interventions: Active rTMS, SHAM rTMS; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 90 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Parkinson's Disease (PD)
Interventions: Clinician-based DBS programming, Maximum Beta power-based DBS programming, Broad-band electrophysiology-based DBS programming; Device
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 89 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Mental Function
Interventions: Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation, Anterior insular cortex (AIC) pulsation, Central thalamus (CT) pulsation; Procedure · Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 40 Years
Enrollment: 168 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Dementia in Nursing Home
Interventions: Cognitive Stimulation Therapy; Other
Lead sponsor: Northern Kentucky University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Lawrenceburg, Indiana

Conditions: Chronic Schizophrenia
Interventions: Transcranial direct current stimulation, Transcranial direct current stimulation - Sham; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 60 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Glen Oaks, New York

Conditions: Deep Brain Stimulation, Parkinson Disease
Interventions: SIS System; Device
Lead sponsor: Surgical Information Sciences Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 10
States / cities: Tucson, Arizona • Little Rock, Arkansas • Hartford, Connecticut + 7 more

Conditions: Treatment Resistant Depression, Epilepsy
Interventions: Device: Directional Deep Brain Stimulation; Device
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 22 Years to 70 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Brain Infarction, Brain Ischemia
Interventions: t DC stimulation, tDCStimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 19 Years to 90 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Obesity
Interventions: Transcranial Direct Current Stimulation (tDCS); Device
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 20 Years to 55 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cervical Dystonia
Interventions: Transcranial magnetic stimulation (TMS); Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Parkinson's Disease, Deep Brain Stimulation
Interventions: Deep brain stimulation; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Alzheimer Disease, Alzheimer Disease, Early Onset, Alzheimer Disease, Late Onset, Alzheimer's Disease (Incl Subtypes), Alzheimer's, Alzheimer's Disease
Interventions: GENUS device (Active Settings), GENUS device (sham settings); Device
Lead sponsor: Massachusetts Institute of Technology; Other
Eligibility: 65 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Adults With Variability in Their Mood
Interventions: Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall, Physiological stimulation; Device · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Epilepsy
Interventions: Not listed
Lead sponsor: Cyberonics, Inc.; Industry
Eligibility: 7 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 7
States / cities: Atlanta, Georgia • Peoria, Illinois • Louisville, Kentucky + 4 more

Conditions: Healthy, Stroke, Traumatic Brain Injury, Multiple Sclerosis
Interventions: Single-pulse transcranial magnetic stimulation (spTMS), Paired associative stimulation (PAS), Repetitive transcranial magnetic stimulation (rTMS); Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 85 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson's Disease
Interventions: Implantation of the Peripheral Nerve Graft; Procedure
Lead sponsor: Craig van Horne, MD, PhD; Other
Eligibility: 40 Years to 75 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 2
States / cities: Lexington, Kentucky

Conditions: Parkinson Disease
Interventions: Real iTBS, Sham iTBS; Device
Lead sponsor: Mark Hallett; NIH
Eligibility: 40 Years to 80 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Brain Injuries, Traumatic, Repetitive Transcranial Magnetic Stimulation, Memory Deficits, Aging
Interventions: Repetitive Transcranial magnetic Stimulation; Device
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 50 Years to 75 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Healthy Participants
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), Computer-based Test, Behavioral-based Test; Device · Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Interventions: Deep Brain Stimulation; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 22 Years to 75 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pain, Low Back Pain, Leg Pain
Interventions: Precision Spinal Cord Stimulation and PET Scan; Other
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Search by objective public record fields.

Deep Brain Stimulation in Treating Patients With Dystonia

Deep Brain Stimulation for the Treatment of Alzheimer's Disease

Cerebello-Cortical Connectivity and Balance Adaptation in Younger and Older Adults

rTMS as a Treatment for PPA

Electrophysiology-based DBS Programming for PD

Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation

Cognitive Stimulation Therapy for Residents With Dementia in Nursing Homes

The Effect of Transcranial Direct Current Stimulation on Human Brains: A Neuroimaging Study

Visualization of the STN and GPi for DBS

Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing

Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm

Enhancement of Brain Circuit of Inhibitory Control in Obese Patients Undergoing Gastric Banding

Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia

Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

Vagus Nerve Stimulation Clinical Outcomes Measured Prospectively in Patients Stimulated

Physiology of Interregional Connectivity in the Human Brain

Autologous Peripheral Nerve Grafts Into the Substantia Nigra of Subjects With PD Undergoing Deep Brain Stimulation

Transcranial Magnetic Stimulation to Treat Parkinson's Disease

Efficacy of Repetitive Transcranial Magnetic Stimulation for Improvement of Memory in Older Adults With TBI

Brain Stimulation and Visually-guided Navigation

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

Changes in Cerebral Blood Flow in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain