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ClinicalTrials.gov public records Last synced Oct 23, 2026, 12:16 PM EDT

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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Breast Augmentation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting

NCT00466765
View directory record Official record
Conditions
Mammaplasty, Mastectomy, Lumpectomy
Interventions
Brava Autologous Fat Transfer System
Device
Lead sponsor
Brava
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
589 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 5, 2015 · Synced Oct 23, 2026, 12:16 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Post Market Clinical Experience Study of Sientra 207 Breast Implants

NCT02905617
View directory record Official record
Conditions
Breast Augmentation, Breast Revision-Augmentation
Interventions
Sientra 207 Silicone Gel Breast Implant
Device
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
22 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 23, 2026, 12:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Safety and Effectiveness of Motiva Implants®

NCT03579901
View directory record Official record
Conditions
Breast Implants
Interventions
Silicone gel-filled breast implants - Motiva Implants® Investigational breast implants
Device
Lead sponsor
Motiva USA LLC
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2033
U.S. locations
27
States / cities
Beverly Hills, California • Santa Monica, California • Westlake Village, California + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Not applicable Interventional

A Prospective Study of Autologous Fat Grafting for Breast Augmentation

NCT00663156
View directory record Official record
Conditions
Breast Augmentation, Fat Grafting
Interventions
breast implants, Liposuction, fat grafting
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Phase 1 Interventional

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women Undergoing Breast Augmentation

NCT04293809
View directory record Official record
Conditions
Breast Augmentation
Interventions
Exparel Injectable Product, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced Oct 23, 2026, 12:16 PM EDT
Completed No phase listed Observational

Study of Health Effects of Cosmetic Breast Augmentation

NCT00342953
View directory record Official record
Conditions
Brain Cancer, Breast Cancer, Lung Cancer, Suicide
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
21 Years to 69 Years · Female only
Enrollment
17,424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Core Study of the Safety and Effectiveness of IDEAL IMPLANT(R) Saline-filled Breast Implants

NCT00858052
View directory record Official record
Conditions
Breast Implants
Interventions
Saline-filled breast implant [IDEAL IMPLANT (R)]
Device
Lead sponsor
Ideal Implant Incorporated
Industry
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2021
U.S. locations
24
States / cities
Beverly Hills, California • Folsom, California • Huntington Beach, California + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Oct 23, 2026, 12:16 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Motiva Implants® Post-Approval Study

NCT06938399
View directory record Official record
Conditions
Breast Implant
Interventions
Silicone gel-filled breast implants - Motiva Implants®, Aesthetic Surgery
Device · Other
Lead sponsor
Motiva USA LLC
Industry
Eligibility
22 Years and older · Female only
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2037
U.S. locations
33
States / cities
Beverly Hills, California • Camp Pendleton, California • Los Gatos, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Phase 2 Interventional Results available

Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammoplasty

NCT01206608
View directory record Official record
Conditions
Postoperative Pain
Interventions
SKY0402 + bupivacaine HCl, Mid-dose SKY0402 + bupivacaine HCl
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Oct 23, 2026, 12:16 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Sientra Post-Approval Study

NCT01639053
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Not listed
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
5,498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2026
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 23, 2026, 12:16 PM EDT
Withdrawn Phase 3 Interventional

Spectra Breast Implant Study

NCT00981266
View directory record Official record
Conditions
Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution, Asymmetry
Interventions
Mentor Spectra/Becker 80 Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
22 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2013 · Synced Oct 23, 2026, 12:16 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation

NCT02008032
View directory record Official record
Conditions
Mammogram Scheduled
Interventions
Stationary Breast Tomosynthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Phase 3 Interventional Results available

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial

NCT00812097
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Mentor Siltex® Contour Profile Gel Mammary Prosthesis
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
955 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 23, 2026, 12:16 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Enhanced Recovery Strategies in Elective Breast Surgery

NCT03187080
View directory record Official record
Conditions
Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use, Satisfaction
Interventions
Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Sham paravertebral block using saline, Paravertebral block using local anesthetic
Procedure · Other · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Phase 3 Interventional Results available

Core Gel Study of the Safety and Effectiveness of Mentor Round Low Bleed Silicone Gel-filled Mammary Prostheses

NCT00753922
View directory record Official record
Conditions
Breast Reconstruction, Breast Augmentation, Breast Revision
Interventions
Mentor Round Low Bleed Gel-filled Mammary Protheses, both Siltex and Smooth Surface
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Style 410 Silicone-Filled Breast Implant Study

NCT00690339
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Revision of Augmentation or Reconstruction
Interventions
Style 410 Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
941 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2014 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery

NCT07807085
View directory record Official record
Conditions
Skin Barrier to Water Loss, Skin Health, Skin Discoloration, Skin Irritation, Skin Abnormalities, Hyperpigmentation, Hyperpigmentation; Melanin, Stretch Mark, Breast Reconstruction, Breast Augmentation and Breast Reconstruction, Chemotherapy Effects, Lymphatic Abnormalities
Interventions
Apple Peptide Complex Post-Aesthetic Care Protocol
Other
Lead sponsor
Grow Out Oils Clinical Aromatherapy Company
Industry
Eligibility
Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Phase 4 Interventional

Bupivacaine HCl PK and Safety in Augmentation Mammoplasty

NCT03705065
View directory record Official record
Conditions
Analgesia
Interventions
Bupivacaine HCl
Drug
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2018 · Synced Oct 23, 2026, 12:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study

NCT01853605
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped silicone gel-filled breast implants
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 11, 2015 · Synced Oct 23, 2026, 12:16 PM EDT
Completed No phase listed Observational Results available

A Pilot Study to Evaluate the BodyLogic TM System (Mentor) in Augmentation Mammaplasty

NCT00684749
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2015 · Synced Oct 23, 2026, 12:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study

NCT01870869
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low height/projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,951 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
58
States / cities
Beverly Hills, California • Campbell, California • Long Beach, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2020 · Synced Oct 23, 2026, 12:16 PM EDT
Recruiting Not applicable Interventional

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

NCT05945329
View directory record Official record
Conditions
Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV
Interventions
GalaFLEX LITE™ Scaffold, Standard surgery
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
22 Years to 70 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
37
States / cities
Scottsdale, Arizona • Beverly Hills, California • Huntington Beach, California + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 23, 2026, 12:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants

NCT01785069
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
29
States / cities
Campbell, California • Palo Alto, California • Pleasanton, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 23, 2026, 12:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00689871
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Revision of Augmentation or Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
715 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2014 · Synced Oct 23, 2026, 12:16 PM EDT