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ClinicalTrials.gov public records Last synced Jun 7, 2026, 6:06 PM EDT

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Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breast Augmentation Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study

NCT01853605
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped silicone gel-filled breast implants
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Jun 7, 2026, 6:06 PM EDT
Withdrawn Phase 3 Interventional

Spectra Breast Implant Study

NCT00981266
View directory record Official record
Conditions
Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution, Asymmetry
Interventions
Mentor Spectra/Becker 80 Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
22 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00691327
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
Female only
Enrollment
84,329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Jun 7, 2026, 6:06 PM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augmentation

NCT00813111
View directory record Official record
Conditions
Pain
Interventions
SKY0402, Bupivacaine HCl
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
15
States / cities
Birmingham, Alabama • Mobile, Alabama • La Jolla, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Seri Surgical Scaffold Support of the Lower Pole of the Breast

NCT02016612
View directory record Official record
Conditions
Recurrent Ptosis of the Breast
Interventions
Seri Surgical Scaffold
Device
Lead sponsor
Bengtson Center
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Phase 2 Interventional Results available

Phase 2B Upper Extremity Nerve Block Study

NCT03011333
View directory record Official record
Conditions
Postoperative Pain
Interventions
HTX-011, Bupivacaine HCl without epinephrine, Saline Placebo
Drug
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older · Female only
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Pasadena, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jun 7, 2026, 6:06 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants

NCT01785069
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
29
States / cities
Campbell, California • Palo Alto, California • Pleasanton, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Jun 7, 2026, 6:06 PM EDT
Recruiting Phase 2 Interventional

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

NCT04683679
View directory record Official record
Conditions
Triple Negative Breast Cancer, TNBC - Triple-Negative Breast Cancer, Breast Cancer, Metastatic Breast Cancer
Interventions
Pembrolizumab, Olaparib, Radiation
Drug · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Phase 3 Interventional Results available

Core Gel Study of the Safety and Effectiveness of Mentor Round Low Bleed Silicone Gel-filled Mammary Prostheses

NCT00753922
View directory record Official record
Conditions
Breast Reconstruction, Breast Augmentation, Breast Revision
Interventions
Mentor Round Low Bleed Gel-filled Mammary Protheses, both Siltex and Smooth Surface
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2012
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2014 · Synced Jun 7, 2026, 6:06 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Post Market Clinical Experience Study of Sientra 207 Breast Implants

NCT02905617
View directory record Official record
Conditions
Breast Augmentation, Breast Revision-Augmentation
Interventions
Sientra 207 Silicone Gel Breast Implant
Device
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
22 Years and older · Female only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00689871
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Revision of Augmentation or Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
715 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Phase 4 Interventional Results available

Study of EXPAREL in Patients Undergoing Breast Augmentation

NCT01582490
View directory record Official record
Conditions
Mammoplasty, Postoperative Pain
Interventions
Instillation - EXPAREL, Infiltration - EXPAREL
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Jun 7, 2026, 6:06 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sientra Post-Approval Study

NCT01639053
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Not listed
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
5,498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

SERI® Surgical Scaffold for Soft Tissue Support in Revision Augmentation Surgery

NCT02030938
View directory record Official record
Conditions
Subjects Requiring Revision Breast Augmentation Surgery
Interventions
SERI® Surgical Scaffold
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
5
States / cities
La Jolla, California • San Francisco, California • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Jun 7, 2026, 6:06 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Grafting of Autologous Adipose Stromal Cell Trial

NCT02116933
View directory record Official record
Conditions
Micromastia
Interventions
Adipose Derived Stem Cells, SVF Enriched Autologous Fat Grafting
Procedure
Lead sponsor
Tower Outpatient Surgical Center
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional

A Prospective Study of Autologous Fat Grafting for Breast Augmentation

NCT00663156
View directory record Official record
Conditions
Breast Augmentation, Fat Grafting
Interventions
breast implants, Liposuction, fat grafting
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

3D Breast Imaging for Cosmetic and Reconstructive Breast Surgery

NCT01964105
View directory record Official record
Conditions
Hypomastia, Primary Breast Augmentation
Interventions
3D Imaging
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 25, 2017 · Synced Jun 7, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

NCT05945329
View directory record Official record
Conditions
Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV
Interventions
GalaFLEX LITE™ Scaffold, Standard surgery
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
22 Years to 70 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
34
States / cities
Scottsdale, Arizona • Beverly Hills, California • Huntington Beach, California + 28 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 7, 2026, 6:06 PM EDT
Completed No phase listed Observational

Study of Health Effects of Cosmetic Breast Augmentation

NCT00342953
View directory record Official record
Conditions
Brain Cancer, Breast Cancer, Lung Cancer, Suicide
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
21 Years to 69 Years · Female only
Enrollment
17,424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Phase 3 Interventional Results available

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial

NCT00812097
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Mentor Siltex® Contour Profile Gel Mammary Prosthesis
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
955 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Jun 7, 2026, 6:06 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation

NCT02008032
View directory record Official record
Conditions
Mammogram Scheduled
Interventions
Stationary Breast Tomosynthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Jun 7, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Motiva Implants® Post-Approval Study

NCT06938399
View directory record Official record
Conditions
Breast Implant
Interventions
Silicone gel-filled breast implants - Motiva Implants®, Aesthetic Surgery
Device · Other
Lead sponsor
Motiva USA LLC
Industry
Eligibility
22 Years and older · Female only
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2037
U.S. locations
30
States / cities
Beverly Hills, California • Camp Pendleton, California • Los Gatos, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Phase 1 Interventional

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women Undergoing Breast Augmentation

NCT04293809
View directory record Official record
Conditions
Breast Augmentation
Interventions
Exparel Injectable Product, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Bellaire, Texas
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jun 7, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Core Study of the Safety and Effectiveness of IDEAL IMPLANT(R) Saline-filled Breast Implants

NCT00858052
View directory record Official record
Conditions
Breast Implants
Interventions
Saline-filled breast implant [IDEAL IMPLANT (R)]
Device
Lead sponsor
Ideal Implant Incorporated
Industry
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2021
U.S. locations
24
States / cities
Beverly Hills, California • Folsom, California • Huntington Beach, California + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Jun 7, 2026, 6:06 PM EDT