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ClinicalTrials.gov public records Last synced Sep 13, 2026, 11:23 AM EDT

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Showing 1–24 of 95 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breast Implant Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting

NCT00466765
View directory record Official record
Conditions
Mammaplasty, Mastectomy, Lumpectomy
Interventions
Brava Autologous Fat Transfer System
Device
Lead sponsor
Brava
Industry
Eligibility
18 Years to 80 Years · Female only
Enrollment
589 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Sep 13, 2026, 11:23 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation

NCT02008032
View directory record Official record
Conditions
Mammogram Scheduled
Interventions
Stationary Breast Tomosynthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Sep 13, 2026, 11:23 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of NATRELLE® 410 Highly Cohesive, Anatomically Shaped, Silicone-filled X-Style and L-Style Breast Implants

NCT01785069
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
29
States / cities
Campbell, California • Palo Alto, California • Pleasanton, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Sep 13, 2026, 11:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Radiologic Evaluation of Changes Following Fat Grafting

NCT01343030
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 84 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 13, 2026, 11:23 AM EDT
Completed No phase listed Observational

SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants

NCT01315119
View directory record Official record
Conditions
Breast Cancer
Interventions
SPY Intra-Operative Angiography
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Sep 13, 2026, 11:23 AM EDT
Active, not recruiting Not applicable Interventional

Memory Gel and Shape Combined Cohort

NCT02919592
View directory record Official record
Conditions
Primary Breast Augmentation, Primary Breast Reconstruction, Revision Breast Augmentation, Revision Breast Reconstruction
Interventions
MemoryShape® Breast Implants, MemoryGel® Breast Implants, Other Aesthetic Surgery
Device · Procedure
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,603 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2031
U.S. locations
78
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Gilbert, Arizona + 64 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 13, 2026, 11:23 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sientra Post-Approval Study

NCT01639053
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Not listed
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
5,498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 13, 2026, 11:23 AM EDT
Active, not recruiting Not applicable Interventional

Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy OPBC-02PREPEC

NCT04293146
View directory record Official record
Conditions
Breast Reconstruction, Implant-Based Breast Reconstruction (IBBR)
Interventions
pre-pectoral IBBR, sub-pectoral IBBR
Procedure
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older · Female only
Enrollment
382 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2033
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional Results available

Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy

NCT03657069
View directory record Official record
Conditions
Breast Carcinoma, Breast Disorder
Interventions
Blossom, Breast-Q -Reconstruction module (preoperative) version 2.0 satisfaction with breasts questionnaire
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 13, 2026, 11:23 AM EDT
Completed No phase listed Observational

Systemic Symptoms: Biospecimen Analysis Study

NCT04255810
View directory record Official record
Conditions
Women With Breast Implants With and Without Self-reported Systemic Symptoms, Women Undergoing an Elective Mastopexy (Breast Lift) or Small Reduction
Interventions
Surgical collection of biospecimens
Procedure
Lead sponsor
Glicksman, Caroline, M.D.
Individual
Eligibility
30 Years to 65 Years · Female only
Enrollment
150 participants
Timeline
2019 – 2023
U.S. locations
1
States / cities
Sea Girt, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 13, 2026, 11:23 AM EDT
Completed No phase listed Observational Results available

A Pilot Study to Evaluate the BodyLogic TM System (Mentor) in Augmentation Mammaplasty

NCT00684749
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older · Female only
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2015 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional

Evaluation of a Human Acellular Dermal Matrix in Post Mastectomy Reconstruction

NCT02263261
View directory record Official record
Conditions
Mastectomy, Breast Reconstruction
Interventions
Flex HD Pliable Perforated HADM
Other
Lead sponsor
Musculoskeletal Transplant Foundation
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Mountain View, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 13, 2026, 11:23 AM EDT
Terminated Not applicable Interventional Results available

Liposomal Bupivacaine in Implant Based Breast Reconstruction

NCT02659501
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain
Interventions
Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate, Hydrocodone/acetaminophen, Diazepam
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional Results available

Sientra Sponsored Silimed Gel-Filled Breast Implant Core Clinical Study

NCT00905645
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Silimed Gel-Filled Mammary Implant
Device
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,788 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2018
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2024 · Synced Sep 13, 2026, 11:23 AM EDT
Withdrawn Not applicable Interventional

Prepectoral vs Partial Subpectoral Two-Stage Implant-Based Breast Reconstruction

NCT04874402
View directory record Official record
Conditions
Breast Reconstruction Following Mastectomy
Interventions
Prepectoral approach, Partial Subpectoral approach
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Jet Hydro Dissection in Breast Augmentation Postoperative Pain

NCT02302001
View directory record Official record
Conditions
Breast Augmentation
Interventions
Silicone Implant
Device
Lead sponsor
Aristocrat Plastic Surgery and MedAesthetics
Other
Eligibility
22 Years to 60 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Great Neck, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional

Pre-pectoral AlloDerm® to Reinforce Tissues in Tissue Expander Breast Reconstruction

NCT03195322
View directory record Official record
Conditions
Postoperative Pain, Postoperative Nausea and Vomiting, Quality of Life, Breast Cancer, Breast Prosthesis; Pain
Interventions
Pre-pectoral Tissue Expander
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Phase 4 Interventional Results available

BLIS - Breastfeeding Levonorgestrel IUD Study

NCT01990703
View directory record Official record
Conditions
Contraception
Interventions
Levonorgestrel IUD
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Albuquerque, New Mexico • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 13, 2026, 11:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adjunct Study of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00691327
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
Female only
Enrollment
84,329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 2012
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Sep 13, 2026, 11:23 AM EDT
Completed No phase listed Observational

Study of Health Effects of Cosmetic Breast Augmentation

NCT00342953
View directory record Official record
Conditions
Brain Cancer, Breast Cancer, Lung Cancer, Suicide
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
21 Years to 69 Years · Female only
Enrollment
17,424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 13, 2026, 11:23 AM EDT
Approved For Marketing No phase listed Expanded access

Mentor Adjunct Study for Silicone Gel-Filled Mammary Prosthesis

NCT00948948
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Silicone Gel-Filled Mammary Prostheses
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Sep 13, 2026, 11:23 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

NCT05846438
View directory record Official record
Conditions
Infections, Quality of Life
Interventions
Showering 48 hours after surgery
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 13, 2026, 11:23 AM EDT
Withdrawn Phase 3 Interventional

Spectra Breast Implant Study

NCT00981266
View directory record Official record
Conditions
Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution, Asymmetry
Interventions
Mentor Spectra/Becker 80 Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
22 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2026
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Sep 13, 2026, 11:23 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study

NCT01853605
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped silicone gel-filled breast implants
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
3,811 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2014
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Sep 13, 2026, 11:23 AM EDT