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ClinicalTrials.gov public records Last synced Jun 7, 2026, 7:42 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Breast Implant Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00689871
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Revision of Augmentation or Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
715 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2014 · Synced Jun 7, 2026, 7:42 PM EDT
Active, not recruiting Not applicable Interventional

Split Chest Breast Neurotization

NCT05757778
View directory record Official record
Conditions
Breast Implant; Complications
Interventions
Sensory Nerve Coaptation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

NCT01624220
View directory record Official record
Conditions
Spinal Tumor
Interventions
Spinal SBRT (Standard Dose), Spinal SBRT (Higher Dose), Gold Seed Implantation, Questionnaires
Radiation · Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sientra Post-Approval Study

NCT01639053
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Not listed
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
5,498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

SERI® Surgical Scaffold for Soft Tissue Support in Revision Augmentation Surgery

NCT02030938
View directory record Official record
Conditions
Subjects Requiring Revision Breast Augmentation Surgery
Interventions
SERI® Surgical Scaffold
Device
Lead sponsor
Sofregen Medical, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
5
States / cities
La Jolla, California • San Francisco, California • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2021 · Synced Jun 7, 2026, 7:42 PM EDT
Active, not recruiting Not applicable Interventional

A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision Reconstruction

NCT02724371
View directory record Official record
Conditions
Breast Reconstruction, Revision Breast Reconstruction
Interventions
Mentor Larger Size MemoryGel Ultra High Profile Breast Implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2029
U.S. locations
30
States / cities
Montgomery, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Not applicable Interventional

A Prospective Study of Autologous Fat Grafting for Breast Augmentation

NCT00663156
View directory record Official record
Conditions
Breast Augmentation, Fat Grafting
Interventions
breast implants, Liposuction, fat grafting
Procedure
Lead sponsor
Georgetown University
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation

NCT05945329
View directory record Official record
Conditions
Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV
Interventions
GalaFLEX LITE™ Scaffold, Standard surgery
Device · Other
Lead sponsor
C. R. Bard
Industry
Eligibility
22 Years to 70 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
34
States / cities
Scottsdale, Arizona • Beverly Hills, California • Huntington Beach, California + 28 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting No phase listed Observational

Molecular Mechanisms Associated With Breast Implant Complications

NCT05736354
View directory record Official record
Conditions
Breast Implant; Complications, Infection or Inflammation
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
3
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Jun 7, 2026, 7:42 PM EDT
Completed No phase listed Observational

Study of Health Effects of Cosmetic Breast Augmentation

NCT00342953
View directory record Official record
Conditions
Brain Cancer, Breast Cancer, Lung Cancer, Suicide
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
21 Years to 69 Years · Female only
Enrollment
17,424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Phase 3 Interventional Results available

Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial

NCT00812097
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Mentor Siltex® Contour Profile Gel Mammary Prosthesis
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
955 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Jun 7, 2026, 7:42 PM EDT
Completed No phase listed Observational

SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants

NCT01315119
View directory record Official record
Conditions
Breast Cancer
Interventions
SPY Intra-Operative Angiography
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786
View directory record Official record
Conditions
Mastectomy, Infections, Breast Reconstruction
Interventions
Culture Swabs, Rodac Plate Cultures
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Jun 7, 2026, 7:42 PM EDT
Terminated Phase 2 Interventional

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

NCT03744715
View directory record Official record
Conditions
NSCLC, Breast Cancer
Interventions
Poziotinib
Drug
Lead sponsor
Spectrum Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
5
States / cities
Long Beach, California • Hattiesburg, Mississippi • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Jun 7, 2026, 7:42 PM EDT
No Longer Available No phase listed Expanded access

Compassionate Use of the Becker Expander/Breast Implant

NCT01000012
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Becker 50 Expander/Breast implant, Becker 25 Expander/Breast implant
Device
Lead sponsor
Mentor Worldwide, LLC
Industry
Eligibility
18 Years and older · Female only
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Jun 7, 2026, 7:42 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation

NCT02008032
View directory record Official record
Conditions
Mammogram Scheduled
Interventions
Stationary Breast Tomosynthesis
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Phase 4 Interventional

Prevention of Post-Mastectomy Breast Pain Using Ambulatory Continuous Paravertebral Blocks

NCT01231204
View directory record Official record
Conditions
Paravertebral Catheter Insertion, Mastectomy, Breast Cancer
Interventions
Placebo (normal saline) Continuous Infusion, Ropivicaine 0.4% Continuous Infusion
Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2016 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Phase 3 Interventional

Tissue Expander/Implant Reconstruction: A Single-Blinded, Randomized, Controlled Trial

NCT00639106
View directory record Official record
Conditions
Breast Cancer
Interventions
Alloderm, Questionnaires, Without ALLODERM, Questionnaires
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
3
States / cities
Ann Arbor, Michigan • New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Jun 7, 2026, 7:42 PM EDT
Completed Phase 1 Interventional

Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy

NCT03213249
View directory record Official record
Conditions
Breast Implant Infection, Mammoplasty
Interventions
Normal saline, Cefazolin, Skin biopsy, Bilateral skin- or nipple-sparing mastectomies, Tissue expander, Breast implant, Autologous flap, Acellular dermal matrix sling, Gentamicin, Bacitracin
Other · Drug · Procedure + 1 more
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

NCT07209436
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Paravertebral block (single injection), Pectoral block
Procedure
Lead sponsor
Amy Colwell
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

NCT05846438
View directory record Official record
Conditions
Infections, Quality of Life
Interventions
Showering 48 hours after surgery
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Motiva Implants® Post-Approval Study

NCT06938399
View directory record Official record
Conditions
Breast Implant
Interventions
Silicone gel-filled breast implants - Motiva Implants®, Aesthetic Surgery
Device · Other
Lead sponsor
Motiva USA LLC
Industry
Eligibility
22 Years and older · Female only
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2037
U.S. locations
30
States / cities
Beverly Hills, California • Camp Pendleton, California • Los Gatos, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 7, 2026, 7:42 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Histological Analysis of AlloMend® Acellular Dermal Matrix Used in Breast Implant Surgeries

NCT05744414
View directory record Official record
Conditions
Breast Implant; Complications, Infection or Inflammation
Interventions
Not listed
Lead sponsor
AlloSource
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jun 7, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blossom® Smart Expander Device for Tissue Expander/Implant-Based Breast Reconstruction

NCT05975372
View directory record Official record
Conditions
Tissue Expansion, Implant Based Breast Reconstruction
Interventions
Blossom tissue expander, Standard tissue expansion
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jun 7, 2026, 7:42 PM EDT